Intra-abdominal myositis ossificans - a clinically challenging disease: A case report

Core Tip

Core Tip: Myositis ossificans (MO) is a rare condition of heterotopic bone formation within muscle or soft tissues. Intra-abdominal MO is even rarer usually arousing following abdominal surgery or trauma. Its presentation is non-specific and physical examination is usually unremarkable until the mass reaches large dimensions. Laboratory examinations are within normal limits. Computed tomography scan is essential for the diagnosis, since it can show the typical “zonal patterns” of the calcifications. Histopathology can differentiate MO from infections and malignancies. However, histology could be misinterpreted for fibromatosis or sarcoma, thus leading to improper cure. The treatment may be complex and should be based on patients’ symptoms. Most patients can be treated conservatively and surgical procedures should be reserved for selected patients since repetitive surgery promotes further and more aggressive calcifications.