©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Oct 18, 2023; 14(10): 771-775
Published online Oct 18, 2023. doi: 10.5312/wjo.v14.i10.771
Published online Oct 18, 2023. doi: 10.5312/wjo.v14.i10.771
Vancomycin flushing syndrome in orthopaedic practice: A case report
Fawaz M Al-Anii, Mir Sadat-Ali, Khalid Waleed Al-Tabash, Ahmad I AlMulhim, Sulaiman A AlMousa, Abdulaziz M AlHawas, Orthopaedic Surgery, Imam AbdulRahman Bin Faisal University and King Fahd Hospital of the University, AlKhobar 31952, Saudi Arabia
Author contributions: Al-Anii FM, Sadat-Ali M, Al-Tabash KW, AlMulhim AI, AlMousa SA, and AlHawas AM participated in the study of the case, review of the literature, and the writing of the manuscript.
Informed consent statement: Informed consent was obtained from the patient to publish the photographs and the data.
Conflict-of-interest statement: All authors declare there are no conflicts of interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Mir Sadat-Ali, FRCS, FRCS (Gen Surg), MBBS, MS, Full Professor, Professor, Senior Scientist, Orthopaedic Surgery, Imam AbdulRahman Bin Faisal University and King Fahd Hospital of the University, Pobox 40071, AlKhobar 31952, Saudi Arabia.
Received: June 13, 2023
Peer-review started: June 13, 2023
First decision: August 16, 2023
Revised: August 16, 2023
Accepted: September 7, 2023
Article in press: September 7, 2023
Published online: October 18, 2023
Processing time: 124 Days and 17.9 Hours
Peer-review started: June 13, 2023
First decision: August 16, 2023
Revised: August 16, 2023
Accepted: September 7, 2023
Article in press: September 7, 2023
Published online: October 18, 2023
Processing time: 124 Days and 17.9 Hours
Core Tip
Core Tip: Vancomycin-related allergic skin reactions are not uncommon and are typically reported to occur after rapid intravenous infusion. However, this complication can also occur when vancomycin is implanted for slow release. Since orthopaedic surgeons routinely use vancomycin with polymethyl methacrylate, they should be aware of this complication occurring despite its rarity.