©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Oct 18, 2022; 13(10): 911-920
Published online Oct 18, 2022. doi: 10.5312/wjo.v13.i10.911
Published online Oct 18, 2022. doi: 10.5312/wjo.v13.i10.911
Adjunctive platelet-rich plasma and hyaluronic acid injection after arthroscopic debridement in Kellgren-Lawrence grade 3 and 4 knee osteoarthritis
Henry Tirtosuharto, I Gede Eka Wiratnaya, Putu Astawa, Department of Orthopaedic and Traumatology, Faculty of Medicine Udayana University/Sanglah Hospital, Denpasar 80113, Bali, Indonesia
Author contributions: Tirtosuharto H designed and conceived the study, collected the data, conducted the data analyses, and drafted the manuscript; Wiratnaya IGE and Astawa P designed and conceived the study, and revised the manuscript.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Faculty of Medicine Udayana University/Sanglah Hospital (Ethical Clearance No. 1847/UN14.2.2.VII.14/LT/2021).
Informed consent statement: Informed consent was not required due to the retrospective nature of the study and anonymized nature of the data.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: The data supporting the findings of this study are not available to be shared publicly due to legal/ethical restrictions.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Corresponding author: I Gede Eka Wiratnaya, Doctor, Consultant Physician-Scientist, Department of Orthopaedic and Traumatology, Faculty of Medicine Udayana University/ Sanglah Hospital, Jalan Diponegoro, Dauh Puri Klod, Denpasar 80113, Bali, Indonesia. igewiratnaya@gmail.com
Received: June 7, 2022
Peer-review started: June 7, 2022
First decision: August 4, 2022
Revised: August 18, 2022
Accepted: September 12, 2022
Article in press: September 12, 2022
Published online: October 18, 2022
Processing time: 132 Days and 4.2 Hours
Peer-review started: June 7, 2022
First decision: August 4, 2022
Revised: August 18, 2022
Accepted: September 12, 2022
Article in press: September 12, 2022
Published online: October 18, 2022
Processing time: 132 Days and 4.2 Hours
Core Tip
Core Tip: This manuscript highlights the alternative approaches in managing knee osteoarthritis of Kellgren-Lawrence grade 3 and 4. Outcomes of arthroscopic debridement, arthroscopic debridement with platelet-rich plasma (PRP), or arthroscopic debridement with hyaluronic acid were evaluated prior to treatment and at 3 mo and 5 mo after the procedure. According to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and sub-scores (pain, stiffness, function), arthroscopic debridement with PRP provided significantly lower pain than arthroscopic debridement after treatment, however neither treatment was superior in the ability to improve total WOMAC score.