BPG is committed to discovery and dissemination of knowledge
Home / Archive / Volume 13, Issue 2
  • This Article
Academic Content and Language Evaluation of This Article
Academic Rules and Norms of This Article
Citation of this article
Corresponding Author of This Article
Research Domain of This Article
Article-Type of This Article
Open-Access Policy of This Article
Times Cited Counts in Google of This Article
Number of Hits and Downloads for This Article
  • Total Article Views (7699)
All Articles published online
The chart showing PDF series, WORD series, HTML series, Figures (1-3) series, Tables (1-10) series.
Item 
Count 
PDF293
WORD80
HTML2612
Figures (1-3)647
Tables (1-10)545
 Sum=4177
Featured Article
The chart showing Browse series, Download series.
Item 
Count 
Browse422
Download1145
 Sum=1567
Publishing Process of This Article
The chart showing Browse series, Download series.
Item 
Count 
Browse622
Download1321
 Sum=1943
Feb 18, 2022 (publication date) through Feb 13, 2026
Times Cited of This Article
Journal Information of This Article
Publication Name
World Journal of Orthopedics
ISSN
2218-5836
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Feb 18, 2022; 13(2): 160-170
Published online Feb 18, 2022. doi: 10.5312/wjo.v13.i2.160
Bone mineral density in fracture neck of femur patients: What's the significance?
Hussam Elamin Ahmed, Oday Al-Dadah
Hussam Elamin Ahmed, Oday Al-Dadah, Department of Trauma and Orthopaedic Surgery, South Tyneside District Hospital, Harton Lane, South Tyneside NE34 0PL, United Kingdom
Oday Al-Dadah, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle-upon-Tyne NE2 4HH, United Kingdom
Author contributions: Elamin Ahmed H contributed to study design, literature review and manuscript production; Al-Dadah O contributed to study design, literature review, statistical analysis and manuscript production.
Institutional review board statement: This was a retrospective observational cohort study which did not require IRB/ Ethics Committee approval.
Informed consent statement: Informed consent was obtained from all patients as part of their routine clinical care in this pragmatic study which evaluated the existing clinical practice within the department.
Conflict-of-interest statement: The authors report no conflict of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Corresponding author: Hussam Elamin Ahmed, MBBS, Doctor, Department of Trauma and Orthopaedic Surgery, South Tyneside District Hospital, Harton Lane, South Tyneside NE34 0PL, United Kingdom. hussam.elamin-ahmed@nhs.net
Received: May 9, 2021
Peer-review started: May 9, 2021
First decision: June 16, 2021
Revised: July 1, 2021
Accepted: January 11, 2022
Article in press: January 11, 2022
Published online: February 18, 2022
Processing time: 284 Days and 16.6 Hours
ARTICLE HIGHLIGHTS
Research background

There has been a steady increase in fragility fractures in the United Kingdom and worldwide. This has been seen in the increased number of patients admitted with fracture neck of femur. It is essential to gain a further understanding of the aetiology to understand preventative measures.

Research motivation

Increased prevalence of osteoporosis fragility fractures in the NHS, causing an increased economic burden.

Research objectives

The aim of this study was to investigate the significance of bone mineral density (BMD) in fracture neck of femur patients and compare it to the outcome of the Fracture Risk Assessment Tool (FRAX) score.

Research methods

Statistical analyses undertaken to ascertain the relationship between BMD and the individual factors included in the FRAX score.

Research results

The results in this study place more emphasis on BMD when assessing fracture risk, in comparison to key factors incorporated into the FRAX predictive score. Menopause age and female gender had an indeterminate influence on BMD, as well as World Health Organization classification of osteoporosis. BMI had a significant influence on BMD. Osteoporosis was more common in patients with extra-capsular hip fracture patterns. This study shows that BMD is significant in assessing risk of fracture neck of femur in comparison to the FRAX predictive score.

Research conclusions

This study demonstrated that BMD of the femoral neck measured by dual-energy X-ray absorptiometry scan is of added prognostic value when assessing patients for risk of fracture neck of femur in combination with the FRAX predictive scoring system.

Research perspectives

The findings in this paper also support the requirement for further research into the use of BMD as a surrogate biomarker for both fracture risk and osteoporosis prevention and management. This may be in the context of a cross-sectional study of fragility fractures at differing ages group and further appropriate stratification as per age, with confounding factors adjusted for.

Write to the Help Desk
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

California Corporate Number: 3537345