Ruan WJ, Xu SS, Xu DH, Li ZP. Orthopedic revolution: The emerging role of nanotechnology. World J Orthop 2024; 15(10): 932-938 [PMID: 39473517 DOI: 10.5312/wjo.v15.i10.932]
Corresponding Author of This Article
Zhi-Peng Li, MM, Surgeon, The Second Department of Orthopedics, The Fifth Affiliated Hospital of Zhengzhou University, No. 3 Kangfuqian Street, Erqi District, Zhengzhou 450015, Henan Province, China. lzpzhonghong@126.com
Research Domain of This Article
Orthopedics
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Orthop. Oct 18, 2024; 15(10): 932-938 Published online Oct 18, 2024. doi: 10.5312/wjo.v15.i10.932
Orthopedic revolution: The emerging role of nanotechnology
Wen-Jie Ruan, Si-Si Xu, Dong-Hui Xu, Zhi-Peng Li
Wen-Jie Ruan, Department of Sports Medicine, Zhejiang Provincial People's Hospital (The Affiliated People's Hospital), Hangzhou 310000, Zhejiang Province, China
Si-Si Xu, Dong-Hui Xu, School of Medicine, Taizhou University, Taizhou 318000, Zhejiang Province, China
Zhi-Peng Li, The Second Department of Orthopedics, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450015, Henan Province, China
Author contributions: Ruan WJ and Xu SS Methodology, software and writing-original draft; Xu DH Visualization and Formal analysis; Li ZP Conceptualization, writing, reviewing and editing; All the authors participated in drafting the manuscript, and all the authors read, contributed to, and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zhi-Peng Li, MM, Surgeon, The Second Department of Orthopedics, The Fifth Affiliated Hospital of Zhengzhou University, No. 3 Kangfuqian Street, Erqi District, Zhengzhou 450015, Henan Province, China. lzpzhonghong@126.com
Received: February 21, 2024 Revised: August 24, 2024 Accepted: September 11, 2024 Published online: October 18, 2024 Processing time: 233 Days and 6.2 Hours
Abstract
This review summarizes the latest progress in orthopedic nanotechnology, explores innovative applications of nanofibers in tendon repair, and evaluates the potential of selenium and cerium oxide nanoparticles in osteoarthritis and osteoblast differentiation. This review also describes the emerging applications of injectable hydrogels in cartilage engineering, emphasizing the critical role of interdisciplinary research and highlighting the challenges and future prospects of integrating nanotechnology into orthopedic clinical practice. This comprehensive approach provides a holistic perspective on the transformative impact of nanotechnology in orthopedics, offering valuable insights for future research and clinical applications.
Core Tip: Nanotechnology has become a new and popular technology in recent years. Combining nanotechnology with orthopedic medicine may open up new treatment methods for orthopedic diseases. Nanotechnology, such as metal nanoparticles, injectable hydrogels and nanofiber scaffolds, can improve the treatment of osteoarthritis, cartilage injury and sports injury. However, in the process of exerting its function, nanotechnology needs to be combined with many disciplines, and it also faces many ethical challenges, which need further research.
