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World J Orthop. Mar 18, 2023; 14(3): 113-122
Published online Mar 18, 2023. doi: 10.5312/wjo.v14.i3.113
Two-stage revision in periprosthetic knee joint infections
Majd M Alrayes, Mohamed Sukeik
Majd M Alrayes, Department of Orthopedics, Imam Abdulrahman bin Faisal University, Khobar 34423, Saudi Arabia
Mohamed Sukeik, Department of Trauma & Orthopaedics, Dr. Sulaiman Al-Habib Hospital – Al Khobar, Al Khobar 34423, Al Khobar, Saudi Arabia
Author contributions: Alrayes M contributed to manuscript writing and literature search; Sukeik M contributed to project supervision, scientific content, and manuscript revision.
Conflict-of-interest statement: All the authors declare having no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mohamed Sukeik, FRCS (Ed), MD, Surgeon, Department of Trauma & Orthopaedics, Dr. Sulaiman Al-Habib Hospital – Al Khobar, King Salman Bin Abdulaziz Rd, Al Bandariyah, Kingdom of Saudi Arabia, Al Khobar 34423, Saudi Arabia. msukeik@hotmail.com
Received: October 12, 2022
Peer-review started: October 12, 2022
First decision: December 13, 2022
Revised: December 20, 2022
Accepted: January 10, 2023
Article in press: January 10, 2023
Published online: March 18, 2023
Processing time: 155 Days and 18 Hours
Abstract

Periprosthetic joint infection (PJI) following total knee arthroplasty is one of the most catastrophic and costly complications that carries significant patient wellness as well as economic burdens. The road to efficiently diagnosing and treating PJI is challenging, as there is still no gold standard method to reach the diagnosis as early as desired. There are also international controversies with respect to the best approach to manage PJI cases. In this review, we highlight recent advances in managing PJI following knee arthroplasty surgery and discuss in depth the two-stage revision method.

Keywords: Periprosthetic joint infection; Knee arthroplasty; Two-stage revision; Spacer; Reimplantation

Core Tip: Two-stage revision for management of periprosthetic joint infection (PJI) following total knee arthroplasty has been widely used with satisfactory outcomes. In this review, we provide comprehensive discussion of the treatment of knee PJI with the two-stage revision method.