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Singh T, Goswami C, Patnaik A, Lendvai L. Optimal Design of Ceramic Based Hip Implant Composites Using Hybrid AHP-MOORA Approach. MATERIALS (BASEL, SWITZERLAND) 2022; 15:3800. [PMID: 35683098 PMCID: PMC9181206 DOI: 10.3390/ma15113800] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 04/07/2022] [Revised: 05/23/2022] [Accepted: 05/23/2022] [Indexed: 02/04/2023]
Abstract
Designing excellent hip implant composite material with optimal physical, mechanical and wear properties is challenging. Improper hip implant composite design may result in a premature component and product failure. Therefore, a hybrid decision-making tool was proposed to select the optimal hip implant composite according to several criteria that are probably conflicting. In varying weight proportions, a series of hip implant composite materials containing different ceramics (magnesium oxide, zirconium oxide, chromium oxide, silicon nitride and aluminium oxide) were fabricated and evaluated for wear and physicomechanical properties. The density, void content, hardness, indentation depth, elastic modulus, compressive strength, wear, and fracture toughness values were used to rank the hip implant composites. It was found that the density and void content of the biocomposites remain in the range of 3.920-4.307 g/cm3 and 0.0021-0.0089%, respectively. The composite without zirconium oxide exhibits the lowest density (3.920 g/cm3), while the void content remains lowest for the composite having no chromium oxide content. The highest values of hardness (28.81 GPa), elastic modulus (291 GPa) and fracture toughness (11.97 MPa.m1/2) with the lowest wear (0.0071 mm3/million cycles) were exhibited by the composites having 83 wt.% of aluminium oxide and 10 wt.% of zirconium oxide. The experimental results are compositional dependent and without any visible trend. As a result, selecting the best composites among a group of composite alternatives becomes challenging. Therefore, a hybrid AHP-MOORA based multi-criteria decision-making approach was adopted to choose the best composite alternative. The AHP (analytic hierarchy process) was used to calculate the criteria weight, and MOORA (multiple objective optimisation on the basis of ratio analysis) was used to rank the composites. The outcomes revealed that the hip implant composite with 83 wt.% aluminium oxide, 10 wt.% zirconium oxide, 5 wt.% silicon nitride, 3 wt.% magnesium oxide, and 1.5 wt.% chromium oxide had the best qualities. Finally, sensitivity analysis was conducted to determine the ranking's robustness and stability concerning the criterion weight.
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Affiliation(s)
- Tej Singh
- Savaria Institute of Technology, Faculty of Informatics, Eötvös Loránd University, 9700 Szombathely, Hungary;
| | - Chandramani Goswami
- Department of Mechanical Engineering, Arya College of Engineering and Information Technology, Jaipur 302028, India;
| | - Amar Patnaik
- Department of Mechanical Engineering, Malaviya National Institute of Technology, Jaipur 302017, India;
| | - László Lendvai
- Department of Materials Science and Engineering, Széchenyi István University, 9026 Gyor, Hungary
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Popov O, Vishnyakov V, Fleming L, Podgurskiy M, Blunt L. Reaction Sintering of Biocompatible Al 2O 3-hBN Ceramics. ACS OMEGA 2022; 7:2205-2209. [PMID: 35071908 PMCID: PMC8771978 DOI: 10.1021/acsomega.1c05749] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 10/14/2021] [Accepted: 12/23/2021] [Indexed: 06/14/2023]
Abstract
Biocompatible Al2O3-hBN ceramic was sintered from AlN and B2O3 precursors by reaction hot pressing at 1750 °C and 30 MPa for 8 min. The ceramic was compared to nonreactive (NR) one sintered from Al2O3 and BN under the same sintering conditions. The NR ceramic possesses 9% porosity as opposed to only 2% porosity for the reaction sintered Al2O3-hBN. The reaction sintered ceramic has crack resistance in the region of 5.0 ± 0.1 MPa·m1/2, which is approximately 20% higher than previously reported pure Al2O3 or Al2O3-hBN sintered without reaction support. The higher amount of hBN in the developed Al2O3-hBN material (27 vol %) facilitates hardness lowering to the region of 6 GPa, which is closer to the bone hardness and makes the ceramic machinable. Reaction sintering of the Al2O3-hBN composite opens a new area of creation and formation of load-bearing Al2O3-hBN ceramic bioimplants.
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Affiliation(s)
- Oleksii Popov
- Metal
Physics Department, Taras Shevchenko National
University of Kyiv, Kyiv 01033, Ukraine
- Science
and Research Center “Synthesis”, Kyiv 02161, Ukraine
| | - Vladimir Vishnyakov
- Centre
for Engineering Materials, University of
Huddersfield, Huddersfield HD1 3DH, U.K.
| | - Leigh Fleming
- Centre
for Precision Engineering, University of
Huddersfield, Huddersfield HD1 3DH, U.K.
| | - Maxim Podgurskiy
- Metal
Physics Department, Taras Shevchenko National
University of Kyiv, Kyiv 01033, Ukraine
| | - Liam Blunt
- Centre
for Precision Engineering, University of
Huddersfield, Huddersfield HD1 3DH, U.K.
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Ten-year survival of ceramic-on-ceramic total hip arthroplasty in patients younger than 60 years: a systematic review and meta-analysis. J Orthop Surg Res 2021; 16:679. [PMID: 34794457 PMCID: PMC8600788 DOI: 10.1186/s13018-021-02828-1] [Citation(s) in RCA: 12] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/19/2021] [Accepted: 11/03/2021] [Indexed: 01/10/2023] Open
Abstract
Background Total hip arthroplasty (THA) with ceramic-on-ceramic (CoC) was created to minimise wear debris and aseptic loosening. A decade ago, a meta-analysis showed a 10-year survival rate of just 89%. Based on the excellent tribology of the current CoC, significant improvement of implant survivorship is expected. In patients younger than 60, we conducted a meta-analysis to assess 10-year survival and complications after using current primary CoC THA. Materials and methods PubMed, Scopus, EMBASE, Virtual Health Library, and Cochrane Library were used to scan for published trials that met the inclusion criteria until January 2019. The qualified studies were subjected to a systematic review and proportional analysis, and the randomised controlled trials (RCTs) were included in a comparison meta-analysis. Results Thirteen studies were included 156 findings. The total number of hips was 2278. Nine studies were cohort, and four were RCTs between ceramic and polyethylene cups. The analysis revealed an average age of 44 years (range 24–54). The 10-year survival 96% (95% CI; 95.4–96.8%), aseptic loosening rate 0.516. (95% CI; 0.265–0.903), ceramic fracture rate 0.620 (95% CI; 0.34–1.034) and squeaking rate 2.687 (95% CI; 1.279–4.593). A comparison meta-analysis revealed the risk ratio (RR) for revision was 0.27 (95% CI; 0.15–0.47), and for aseptic loosening 0.15 (0.03–0.70) favouring CoC, while RR for component fracture was 1.62 (95% CI; 0.27–9.66) favouring the polyethylene. Conclusion In patients under sixty, current CoC THAs are correlated with better 10-year outcomes than before and have high survivorship rates. Level of evidence: Level I.
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Incidence, Risk Factors, and Outcome of Ceramic-On-Ceramic Bearing Breakage in Total Hip Arthroplasty. J Arthroplasty 2021; 36:2992-2997. [PMID: 33812710 DOI: 10.1016/j.arth.2021.03.021] [Citation(s) in RCA: 6] [Impact Index Per Article: 1.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/23/2021] [Revised: 03/02/2021] [Accepted: 03/04/2021] [Indexed: 02/02/2023] Open
Abstract
BACKGROUND Ceramic-on-ceramic bearing breakage is a rare but significant complication of total hip arthroplasty. This study aimed to identify risk factors for breakage and to determine the outcome of different revision options. METHODS All ceramic-on-ceramic primary total hip arthroplasty procedures reported to the Australian Joint Replacement Registry from September 1999 to December 2019 were included. Procedures were subdivided into alumina or mixed ceramic (alumina/zirconia). All breakages were identified. The association between ceramic type and head size was assessed. Subsequent revision rates were compared and cause of revision assessed. RESULTS There were 23,534 alumina and 71,144 mixed ceramic procedures. Breakage was the reason for 1st revision in 84 alumina (5.27% of all revisions and 0.36% of procedures) and 56 mixed ceramic procedures (2.46% of all revisions; 0.08% of procedures). Alumina had a higher breakage rate than mixed ceramic (HR 2.50 (95% CI 1.75, 3.59), P < .001), and breakage was higher for 36-38mm head sizes using alumina (HR 2.84 (1.52, 5.31), P = .001). 17.8% of 2nd revisions occur by 3 years, due to dislocation, infection, metal-related pathology, and loosening. A neck adapter sleeve did not reduce 2nd revisions. Numbers were too low to compare revision bearing surface options. CONCLUSION Ceramic breakage has reduced with mixed ceramics but has a 0.79/1000 incidence at 15-year follow-up. It is unclear what the risk factors are for modern ceramics with increasing head size a risk for alumina only. Risk of 2nd revision is high and occurs early. The optimal revision option is unknown.
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Fernández-Fairén M, Torres-Perez A, Perez R, Punset M, Molmeneu M, Ortiz-Hernández M, Manero JM, Gil J. Early Short-Term Postoperative Mechanical Failures of Current Ceramic-on-Ceramic Bearing Total Hip Arthroplasties. MATERIALS 2020; 13:ma13235318. [PMID: 33255355 PMCID: PMC7727787 DOI: 10.3390/ma13235318] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 10/26/2020] [Revised: 11/19/2020] [Accepted: 11/20/2020] [Indexed: 12/01/2022]
Abstract
Although ceramic-on-ceramic (CoC) bearings have been shown to produce the smallest amount of wear volume in vitro as well as in vivo studies when used for total hip arthroplasties (THA), concerns about the failure of these bearing surfaces persist due to early failures observed after short postoperative time. In this study, an exhaustive analysis of the early failure occurred on the new generation of ceramic bearings, consisting of a composite alumina matrix-based material reinforced with yttria-stabilized tetragonal zirconia (Y-TZP) particles, chromium dioxide, and strontium crystals, was performed. For this study, 118 CoC bearings from 117 patients were revised. This article describes a group of mechanical failure CoC-bearing BIOLOX THA hip prosthesis patients without trauma history. The retrieved samples were observed under scanning electron microscopy (SEM), composition was analyzed with energy dispersive X-ray spectroscopy (EDX), and damaged surfaces were analyzed by grazing-incidence X-ray diffraction (GI-XRD) and white light interferometry. In the short term, CoC articulations provided similar mechanical behavior and functional outcome to those in XLPE cases. However, 5% more early mechanical failures cases were observed for the ceramic components. Although the fracture rate of third generation CoC couples is low, the present study shows the need to further improve the third generation of CoC-bearing couples for THA. Despite the improved wear compared to other materials, stress concentrators are sources of initial crack propagation, such as those found in the bore-trunnion areas. Moreover, in view of the evidence observed in this study, the chipping observed was due to the presence of monoclinic phase of the Y-TZP instead of tetragonal, which presents better mechanical properties. The results showed that total safety after receiving a THA is still a goal to be pursued.
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Affiliation(s)
- Mariano Fernández-Fairén
- Bioengineering Institute of Technology, Facultat de Medicina y Ciencias de la Salud, Universitat Internacional de Catalunya, 080195 Barcelona, Spain; (M.F.-F.); (R.P.)
| | - Ana Torres-Perez
- Hospital Universitario Santa Lucía, Calle Mezquita, s/n, 30202 Cartagena, Spain;
| | - Roman Perez
- Bioengineering Institute of Technology, Facultat de Medicina y Ciencias de la Salud, Universitat Internacional de Catalunya, 080195 Barcelona, Spain; (M.F.-F.); (R.P.)
| | - Miquel Punset
- Biomaterials, Biomechanics and Tissue Engineering Group (BBT), Department of Materials Science and Engineering, Escola d’Enginyeria de Barcelona Est (EEBE), Universitat Politècnica de Catalunya (UPC), Carrer de Jordi Girona 1, 08034 Barcelona, Spain; (M.P.); (M.M.); (M.O.-H.); (J.M.M.)
- Barcelona Research Centre in Multiscale Science and Engineering, Technical University of Catalonia (UPC), Av. Eduard Maristany, 10–14, 08019 Barcelona, Spain
- UPC Innovation and Technology Center (CIT-UPC), Technical University of Catalonia (UPC), C. Jordi Girona 3–1, 08034 Barcelona, Spain
| | - Meritxell Molmeneu
- Biomaterials, Biomechanics and Tissue Engineering Group (BBT), Department of Materials Science and Engineering, Escola d’Enginyeria de Barcelona Est (EEBE), Universitat Politècnica de Catalunya (UPC), Carrer de Jordi Girona 1, 08034 Barcelona, Spain; (M.P.); (M.M.); (M.O.-H.); (J.M.M.)
- Barcelona Research Centre in Multiscale Science and Engineering, Technical University of Catalonia (UPC), Av. Eduard Maristany, 10–14, 08019 Barcelona, Spain
| | - Monica Ortiz-Hernández
- Biomaterials, Biomechanics and Tissue Engineering Group (BBT), Department of Materials Science and Engineering, Escola d’Enginyeria de Barcelona Est (EEBE), Universitat Politècnica de Catalunya (UPC), Carrer de Jordi Girona 1, 08034 Barcelona, Spain; (M.P.); (M.M.); (M.O.-H.); (J.M.M.)
- Barcelona Research Centre in Multiscale Science and Engineering, Technical University of Catalonia (UPC), Av. Eduard Maristany, 10–14, 08019 Barcelona, Spain
| | - José María Manero
- Biomaterials, Biomechanics and Tissue Engineering Group (BBT), Department of Materials Science and Engineering, Escola d’Enginyeria de Barcelona Est (EEBE), Universitat Politècnica de Catalunya (UPC), Carrer de Jordi Girona 1, 08034 Barcelona, Spain; (M.P.); (M.M.); (M.O.-H.); (J.M.M.)
- Barcelona Research Centre in Multiscale Science and Engineering, Technical University of Catalonia (UPC), Av. Eduard Maristany, 10–14, 08019 Barcelona, Spain
| | - Javier Gil
- Bioengineering Institute of Technology, Facultat de Medicina y Ciencias de la Salud, Universitat Internacional de Catalunya, 080195 Barcelona, Spain; (M.F.-F.); (R.P.)
- Correspondence:
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Prabowo Y, Saleh I, Pitarini A, Junaidi MA. Management of synovial chondromatosis of the hip by open arthrotomy debridement only VS total hip replacement: A case report. Int J Surg Case Rep 2020; 74:289-295. [PMID: 32773292 PMCID: PMC7503789 DOI: 10.1016/j.ijscr.2020.07.042] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/19/2020] [Revised: 06/29/2020] [Accepted: 07/03/2020] [Indexed: 11/04/2022] Open
Abstract
Both arthrotomy debridement only or followed by total hip replacement could be an option in treating synovial chondromatosis of the hip. Both treatment option shows a successful outcome by HHS and LEFS questionnaires without any recurrence marks. Grade of osteoarthritis and patient age can be a distinguish factor for choosing a treatment option. Introduction Synovial chondromatosis is an unusual nonneoplastic condition of joints. Clinical symptoms usually insidious, and the patient often came in the late stage of the disease. Treatment generally include arthroscopy debridement, open arthrotomy debridement to evacuate loose bodies, or in a very late stage with a collapsing joint, it might need a joint replacement arthroplasty. Methods We report two cases of a 55-year old and a 22-year-old man with synovial chondromatosis of the hip. Both patients came with hip pain, but the former presents at a late stage with osteoarthritis of the hip. The former underwent open arthrotomy debridement to evacuate loose bodies, synovectomy then followed by a total hip replacement. The latter underwent open arthrotomy debridement only to evacuate loose bodies and synovectomy without performing dislocation of the hip. Postoperative outcome was evaluated using plain hip x-ray, pain scale with VAS, and functional score with Harris Hip Score (HHS). Results At 1-year follow up, both subjects demonstrate an improving functional outcome. The former patient had an improved HHS from 39 to 91 while the latter had an improved HHS from 68 to 93. With complete removal of the metaplastic tissue and synovectomy, the recurrence of the chondromatosis is not apparent yet until now. Discussion Arthrotomy debridement only or arthrotomy debridement followed by total hip replacement can be considered as an option in treating synovial chondromatosis of the hip as both show a successful outcome. A selective method of treatment must be considered in our decision making for each individual.
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Affiliation(s)
- Yogi Prabowo
- Department of Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital - Faculty of Medicine Universitas Indonesia, Jakarta, 10430, Indonesia
| | - Ifran Saleh
- Department of Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital - Faculty of Medicine Universitas Indonesia, Jakarta, 10430, Indonesia
| | - Astuti Pitarini
- Orthopaedics and Traumatology, St Carolus Hospital, Jakarta, 10440, Indonesia
| | - Muhammad Ade Junaidi
- Department of Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital - Faculty of Medicine Universitas Indonesia, Jakarta, 10430, Indonesia.
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Lohmann CH, Hameister R, Singh G. Allergies in orthopaedic and trauma surgery. Orthop Traumatol Surg Res 2017; 103:S75-S81. [PMID: 28043850 DOI: 10.1016/j.otsr.2016.06.021] [Citation(s) in RCA: 26] [Impact Index Per Article: 3.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/11/2016] [Revised: 05/26/2016] [Accepted: 06/07/2016] [Indexed: 02/02/2023]
Abstract
Hypersensitivity reactions to implants in orthopaedic and trauma surgery are a rare but devastating complication. They are considered as a delayed-type of hypersensitivity reaction (type IV), characterized by an antigen activation of sensitized T-lymphocytes releasing various cytokines and may result in osteoclast activation and bone resorption. Potential haptens are originated from metal alloys or bone-cement. A meta-analysis has confirmed a higher probability of developing a metal hypersensitivity postoperatively and noted a greater risk of failed replacements compared to stable implants. Hypersensitivity to implants may present with a variety of symptoms such as pain, joint effusion, delayed wound/bone healing, persistent secretion, allergic dermatitis (localized or systemic), clicking noises, loss of joint function, instability and failure of the implant. Various diagnostic options have been offered, including patch testing, metal alloy patch testing, histology, lymphocyte transformation test (LTT), memory lymphocyte immunostimulation assay (MELISA), leukocyte migration inhibition test (LIF) and lymphocyte activation test (LAT). No significant differences between in vivo and in vitro methods have been found. Due to unconvincing evidence for screening methods, predictive tests are not recommended for routine performance. Infectious aetiology always needs to be excluded. As there is a lack of evidence on large-scale studies with regards to the optimal treatment option, management currently relies on individual case-by-case decisions. Several options for patients with (suspected) metal-related hypersensitivity exist and may include materials based on ceramic, titanium or oxinium or modified surfaces. Promising results have been reported, but long-term experience is lacking. More large-scaled studies are needed in this context. In patients with bone-cement hypersensitivity, the component suspected for hypersensitivity should be avoided. The development of (predictive) biomarkers is considered as a major contribution for the future.
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Affiliation(s)
- C H Lohmann
- Department of Orthopaedic Surgery, Otto-von-Guericke University, 44, Leipziger Strasse, 39120 Magdeburg, Germany.
| | - R Hameister
- Department of Orthopaedic Surgery, Otto-von-Guericke University, 44, Leipziger Strasse, 39120 Magdeburg, Germany; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4, Medical Drive, 117594, Singapore
| | - G Singh
- Division of Musculoskeletal Oncology, University Orthopaedics, Hand and Reconstructive Microsurgery Cluster, National University Health System, 1E, Kent Ridge Road, 119228, Singapore
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Puccio FD, Mattei L. Biotribology of artificial hip joints. World J Orthop 2015; 6:77-94. [PMID: 25621213 PMCID: PMC4303792 DOI: 10.5312/wjo.v6.i1.77] [Citation(s) in RCA: 44] [Impact Index Per Article: 4.4] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/28/2013] [Revised: 03/25/2014] [Accepted: 05/14/2014] [Indexed: 02/06/2023] Open
Abstract
Hip arthroplasty can be considered one of the major successes of orthopedic surgery, with more than 350000 replacements performed every year in the United States with a constantly increasing rate. The main limitations to the lifespan of these devices are due to tribological aspects, in particular the wear of mating surfaces, which implies a loss of matter and modification of surface geometry. However, wear is a complex phenomenon, also involving lubrication and friction. The present paper deals with the tribological performance of hip implants and is organized in to three main sections. Firstly, the basic elements of tribology are presented, from contact mechanics of ball-in-socket joints to ultra high molecular weight polyethylene wear laws. Some fundamental equations are also reported, with the aim of providing the reader with some simple tools for tribological investigations. In the second section, the focus moves to artificial hip joints, defining materials and geometrical properties and discussing their friction, lubrication and wear characteristics. In particular, the features of different couplings, from metal-on-plastic to metal-on-metal and ceramic-on-ceramic, are discussed as well as the role of the head radius and clearance. How friction, lubrication and wear are interconnected and most of all how they are specific for each loading and kinematic condition is highlighted. Thus, the significant differences in patients and their lifestyles account for the high dispersion of clinical data. Furthermore, such consideration has raised a new discussion on the most suitable in vitro tests for hip implants as simplified gait cycles can be too far from effective implant working conditions. In the third section, the trends of hip implants in the years from 2003 to 2012 provided by the National Joint Registry of England, Wales and Northern Ireland are summarized and commented on in a discussion.
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Heiner AD, Mahoney CR. Fracture of a BIOLOX Delta Ceramic Femoral Head Articulating Against a Polyethylene Liner: A Case Report. JBJS Case Connect 2014; 4:e97. [PMID: 29252765 DOI: 10.2106/jbjs.cc.n.00040] [Citation(s) in RCA: 9] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 06/07/2023]
Abstract
CASE A forty-five-year-old woman underwent primary total hip arthroplasty with a 36-mm BIOLOX delta ceramic femoral head articulating against a polyethylene liner. She presented with hip pain at eighteen months postoperatively, two months after being in a bicycle accident; fracture of the femoral head was diagnosed. CONCLUSION The possibility of a ceramic femoral head fracture should be decreased with use of the latest generation of ceramic material, a ceramic-on-polyethylene articulation rather than a ceramic-on-ceramic articulation, and a larger head size, all of which applied to this case. Taper-trunnion compatibility and correct intraoperative handling of the components are also essential.
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Affiliation(s)
- Anneliese D Heiner
- Department of Orthopaedics and Rehabilitation and Department of Biomedical Engineering, Orthopaedic Biomechanics Laboratory, University of Iowa, 2181 Westlawn Building, Iowa City, IA 52242-1100.
| | - Craig R Mahoney
- Iowa Orthopaedic Center, 450 Laurel Street, Des Moines, IA 50314
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