Levels of neutrophil gelatinase-assosciated lipocalin in patients with head and neck squamous cell carcinoma in Indian population from Haryana state

Table 1 Biochemical parameters in head and neck squamous cell carcinoma patients and healthy controls

Parameter	HNSCC patients	Healthy controls
n	50	50
Age (yr)	57.40 ± 12.61	40.01 ± 10.8
Gender (M:F)	40:10	38:12
Smoker:non-smoker	40:10	12:38
Serum NGAL (ng/mL)	a978.88 ± 261.39	34.83 ± 7.59

^aSignificant; all values are in mean ± SD. HNSCC: Head and neck squamous cell carcinoma; NGAL: Neutrophil gelatinase-associated lipocalin.

Table 2 Correlation between neutrophil gelatinase-associated lipocalin levels and various study variables

	n	Serum NGAL (mean ± SD)
Differentiation
Well differentiated	10	11164 ± 315.64
Moderately differentiated	36	1013.33 ± 161.19
Poorly differentiated	4	890 ± 11.55
Site
Base of tongue	18	11072.22 ± 251.39
Larynx	19	1037.89 ± 217.35
Tonsil	11	947.27 ± 50.02
Cheeks	2	1120 ± 0.00
Metastasis
No	49	1036.73 ± 206.64
Yes	1	880 ± 0.00
Staging
I	2	1040 ± 0.00
II	1	900 ± 0.00
III	21	1031.90 ± 202.55
IV	26	11041.54 ± 222.15
Smoking
Smoker	40	1051 ± 223.57
Non-smoker	10	964 ± 84.22

¹Highly significant. All values are in mean ± SD. NGAL: Neutrophil gelatinase-associated lipocalin.