Gastric and duodenal polyps in familial adenomatous polyposis patients: Conventional endoscopy vs virtual chromoendoscopy (fujinon intelligent color enhancement) in dysplasia evaluation

Table 1 Demographic features

Features	Patients
Total	76
Age (yr)	Mean 40.3 (24-64)
Gender
Male	41 (53.9%)
Female	35 (46.1%)
Prior surgery
IRA	10 (13.2%)
IPAA	66 (86.8%)
Chemoprevention	16 (21.1%)
NSAIDS intake	17 (22.4%)
Tobacco exposure	21 (27.6%)
PPI/anti-H2 intake	14 (18.4%)
Family history of GI malignancies
None	31 (40.8%)
1 member	32 (42.1%)
2 members	10 (13.2%)
3 members	3 (3.9%)
Spigelman duodenal stage
0	28 (36.8%)
I	7 (9.2%)
II	34 (44.8%)
III	7 (9.2%)
IV	0 (0.0%)

IRA: Total colectomy and ileo-rectal anastomosis; IPAA: Total proctocolectomy and ileopouch-anal anastomosis; NSAIDS: Non steroidal anti-inflammatory drugs; PPI: Proton pump inhibitors.

Table 2 Stomach and duodenum polyps

	Patients		Patients
Fundus	34 (49.3%)	Bulb	7 (13.5%)
Antrum	7 (10.1%)	Ii°/iii° portion	35 (67.3%)
Fundus + antrum	28 (40.6%)	Bulb+ii°/iii°	10 (19.2%)
Total stomach	69 (100%)	Total duodenum	52 (100%)

Table 3 Features of fundic polyps identified by white light endoscopy

	P1-P3	P4-P10	P11-P24	P25-P55	P56-P397
Kudo	I	II	II	II	I
Size (mm)	5	5	6-10	5	5
Paris CL	Is	Is	Is	Is	Is
Histology	HYP	IN	FGP	FGP	FGP

IN: Inflammatory; FGP: Fundic gland polyp; IP: Hyperplastic.

Table 4 Features of fundic polyps identified by fujinon intelligent color enhancement

	P1-P6	P7-P10
Kudo	IIIS	IIIL
Size (mm)	5	5
Paris CL	Is	Is
Histology	FGP	FGP

FGP: Fundic gland polyp.

Table 5 Features of antral polyps identified by white light endoscopy

	P1-P3	P4	P5-P10	P11-P17	P18-P24
Kudo	II	IIIS	IIIS	IIIS	IV
Size (mm)	6-10	6-10	5	5	5
Paris CL	IIa	IIa + IIc	Is	Is	Is
Histology	IN	TA, LGD	TA, LGD	TA, LGD	TA, LGD
Spigelman	0	0	I°	0	0

IN: Inflammatory; TA: Tubular adenoma; LGD: Low grade dysplasia.

Table 6 Features of antral polyps identified by fujinon intelligent color enhancement

	P25	P26	P27	P28-P30	P31	P32-P33	P34-P35	P36-P38	P39-P44	P45-P49	P50-P53	P54-P56
Kudo	V	V	IIIS	IIIL	IIIL	IV	IV	IIIL	IIIL	IIIS	IIIS	V
Size (mm)	5	5	5	6-10	5	5	6-10	5	5	5	6-10	5
Paris CL	IIb	IIa	IIb	IIb	IIa	IIb	IIa	IIa	IIb	IIb	Is	IIb
Histology	IN LGD	IN LGD	IN LGD	MET	MET	MET	MET	IN	IN	IN	TA LGD	TA LGD
Spigelman	III°	II°	I°	II°	II°	0	II°	0	0	0	I°	II°

IN: Inflammatory; TA: Tubular adenoma; LGD: Low grade dysplasia; MET: Metaplasia.

Table 7 Features of bulbal polyps identified by white light endoscopy

	P1-P5	P6-P8	P9	P10-P12	P13	P14
Kudo	II	IIIS	IIIS	IIIL	IV	IV
Size (mm)	5	6-10	6-10	5	6-10	6-10
Paris CL	Is	Is	Is	IIa	Is	Is
Histology	IN	TA LGD	TA LGD	IN	TA LGD	TA LGD
Spigelman	0	II°	I°	0	III°	II°

TA: Tubular adenoma; LGD: Low grade dysplasia.

Table 8 Features of bulbal polyps identified by fujinon intelligent color enhancement

	P15	P16-P17	P18	P19	P20-P21
Kudo	IIIS	IV	IIIS	IIIL	IIIS
Size (mm)	5	6-10	6-10	5	5
Paris CL	IIa	IIb	IIa	IIb	IIb
Histology	TA LGD	TA LGD	TA LGD	TA LGD	TA LGD
Spigelman	I°	II°	II°	I°	I°

TA: Tubular adenoma; LGD: Low grade dysplasia.

Table 9 Features of duodenal polyps identified by white light endoscopy

	Kudo	Size (mm)	Paris CL	Histology	Spigelman
P1-P4	IV	11-20	IIa	TA LGD	III°
P5-P7	V	6-10	IIa	TA LGD	II°
P8-P11	IV	5	IIb	TA LGD	II°
P12-P16	IIIS	6-10	IIa	TVA LGD	III°
P17-P27	IIIS	5	IIa	TA LGD	II°
P28-P34	IIIS	5	IIa	TA LGD	I°
P35-P40	IIIS	5	IIb	TA LGD	II°
P41-P43	IIIS	5	Is	TA LGD	II°
P44-P47	IIIS	5	Is	TA LGD	I°
P48-P50	IIIS	11-20	IIa	TA LGD	II°
P51-P58	IIIL	5	IIb	TA LGD	II°
P59-P65	IIIL	5	IIa	TA LGD	II°
P66-P68	IIIL	6-10	IIa	TA LGD	II°
P69-P72	IIIL	6-10	IIa	TA LGD	III°
P73-P79	IIIL	6-10	IIb	TA LGD	II°
P80-P84	II	5	IIa	TA LGD	III°
P85-P91	IIIL	5	IIb	IN	II°
P92-P94	IIIS	5	IIa	IN	I°

IN: Inflammatory; TA: Tubular adenoma; LGD: Low grade dysplasia.

Table 10 Features of duodenal polyps identified by fujinon intelligent color enhancement

	P95-P97	P98-P100	P101-P102	P103-P105
Kudo	IV	IV	V	IV
Size (mm)	5	6-10	6-10	5
Paris CL	IIa	IIb	IIb	IIb
Histology	TA LGD	TA LGD	TA LGD	TA LGD
Spigelman	I°	II°	II°	II°

TA: Tubular adenoma; LGD: Low grade dysplasia.