Bioactive substances with anti-neoplastic efficacy from marine invertebrates: Bryozoa, Mollusca, Echinodermata and Urochordata

Table 1 The most important bioactive substances with anti-neoplastic effects isolated from Bryozoa, Mollusca, and deuterostomian invertebrates

Component	Species	Ref.
Bryostatin-1	Bugula neritina (bryozoan)	[1]
Pterocellins	Pterocella vesiculosa (bryozoan)	[12]
Dolabellanins	Dolabella auricularia (mollusc)	[14]
Dolastatins	Dolabella auricularia (mollusc)	[17]
Aplyronine A	Aplysia kurodai (mollusc)	[19]
Jorunnamycins A-C	Jorunna funebris (mollusc)	[24]
Kahalalide F	Elysia rubefescens (mollusc)	[25]
Lamellarins	Lamellaria sp./Didemnum sp. (mollusc/tunicate)	[28,39]
Intercedensides	Mensamaria intercedents (echinoderm)	[23]
Philinopgeneins	Pentacta quadrangularis (echinoderm)	[23]
Colochirosid	Colochirous anceps (echinoderm)	[23]
Ritterazine A	Ritterella tokioka (tunicate)	[33]
Ecteinascidins	Ecteinascidia turbinate (tunicate)	[34]
Cystodytins	Cystodytes dellechiajei (tunicate)	[38]
Didemnins	Trididemnum solidum (tunicate)	[41]
Ascidiacyclamide	Lissoclinum patella (tunicate)	[44]
Cephalostatin 1	Cephalodiscus gilchristi (hemichordate)	[50]