Validation of the prognostic model for palliative radiotherapy in older patients with cancer

Table 1 Patients characteristics, n (%)

Characteristics	Total (n = 33)
Age (years)
Median	82
Range	80-92
Gender
Male	23 (69.7)
Female	10 (30.3)
ECOG
0	1 (3.0)
1	12 (36.4)
2	13 (39.4)
3	7 (21.2)
4	0
Primary site of neoplasm
Lung	13 (39.4)
Gastrointestinal	7 (21.2)
Genitourinary	5 (15.2)
Others	11 (24.2)
Distant metastasis
No	9 (27.3)
Yes	24 (72.7)
Previous treatment
No	17 (51.5)
Surgery	6 (18.2)
Chemotherapy	6 (18.2)
Radiotherapy	1 (3.0)
Others	3 (9.1)

ECOG: Eastern Cooperative Oncology Group.

Table 2 Distribution of prognosis in palliative care study, palliative prognostic index and delirium-palliative prognostic score without clinical prediction, n (%)

Variable	Total (n = 33)
PiPS
Months+ (> 55 days)	27 (81.8)
Weeks (14-55 days)	6 (18.2)
Days (0-13 days)	0
PPI
< 4	28 (84.8)
≥ 4	5 (15.2)
D-PaP without CPS
< 4	28 (84.8)
≥ 4	5 (15.2)

PiPS: Prognosis in palliative care study; PPI: Palliative prognostic index; D-PaP: Delirium-palliative prognostic score; CPS: Clinical prediction of survival.

Table 3 Prognostic factors affecting treatment response upon logistic regression analysis

Characteristics	OR (95%CI)	P value
Age	0.807 (0.579-1.126)	0.207
ECOG	0.956 (0.303-3.022)	0.940
Symptoms (pain vs others)	2.833 (0.389-20.179)	0.298
Treatment site (bone vs brain vs others)	0.834 (0.299-2.325)	0.728
Radiation dose, BED	1.021 (0.942-1.106)	0.610
PiPS (Months vs Weeks)	1.375 (0.120-15.721)	0.798
PPI (< 4 vs ≥ 4)	5.111 (0.592-44.146)	0.138
D-PaP without CPS (< 4 vs ≥ 4)	1.375 (0.120-15.721)	0.798

ECOG: Eastern Cooperative Oncology Group; BED: Biologically effective dose; PiPS: Prognosis in palliative care study; PPI: Palliative prognostic index; D-PaP: Delirium-palliative prognostic score; CPS: Clinical prediction of survival.