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©The Author(s) 2021.
World J Clin Oncol. Nov 24, 2021; 12(11): 1000-1008
Published online Nov 24, 2021. doi: 10.5306/wjco.v12.i11.1000
Published online Nov 24, 2021. doi: 10.5306/wjco.v12.i11.1000
Ref. | n | Outcomes | CMS1, mean (95%CI) | CMS2, mean (95%CI) | CMS3, mean (95%CI) | CMS4, mean (95%CI) |
Stages I-IV | ||||||
Purcell et al[39], 2019 | 257 | 5-yr OS (%) | 63.7 (51.1-79.4) | 64.4 (56.6-73.4) | 52.8 (37.1-75.1) | 42.8 (23.8-76.8) |
5-yr PFS (%) | 61.2 (48.8-76.8) | 59.8 (51.8-68.9) | 52.7 (47.5-74.0) | 38.8 (21.0-71.9) | ||
Guinney et al[8], 2015 | 2129 | 5-yr OS (%) | 74 (70-75) | 77 (74-80) | 75 (70-80) | 62 (58-66) |
5-yr DFS (%) | 75 (70-80) | 73 (70-77) | 73 (68-80) | 60 (55-65) | ||
Stage II | ||||||
Shinto et al[36], 2020 | 232 | 5-yr DFS (%) | 100 | 85.5 | 92.3 | 73 |
Stage IV | ||||||
Borelli et al[43], 2021 | 426 | OS (mo) | 13.7 (6.1-27.9) | 27.0 (23.9-30.1) | 18.3 (16.1-24.0) | 26.2 (21.4-29.9) |
PFS (mo) | 5.4 (3.8-9.9) | 12.9 (11.0-14.3) | 8.3 (7.4-10.1) | 10.7 (9.8-13.1) | ||
Stintzing et al[20], 2019 | 438 | OS (mo) | 15.9 (11.0-20.8) | 29.0 (26.7-31.4) | 18.6 (15.4-21.7) | 24.8 (22.6-27.1) |
PFS (mo) | 8.2 (6.7-9.6) | 11.7 (10.8-12.6) | 8.5 (6.8-10.3) | 9.6 (8.6-10.6) | ||
Lenz et al[16], 2019 | 581 | OS (mo) | 15.0 (11.7-22.4) | 40.3 (36.1-43.1) | 24.3 (16.4-29.0) | 31.4 (26.3-36.9) |
PFS (mo) | 7.1 (5.7-8.6) | 13.4 (12.8-15.4) | 8.7 (7.2-9.8) | 11.0 (9.7-12.0) | ||
Mooi et al[41], 2018 | 237 | OS (mo) | 8.8 (6.5-16.0) | 24.2 (19.1-27.4) | 17.6 (11.3-24.6) | 21.4 (15.8-23.1) |
PFS (mo) | No statistical differences in this cohort | |||||
Okita et al[42], 2018 | 193 | OS (mo) | 21.4 (13.3-35.5) | 48.1 (34.8-65.6) | 38.7 (30.6-45.6) | 44.0 (33.0-50.5) |
- Citation: Valenzuela G, Canepa J, Simonetti C, Solo de Zaldívar L, Marcelain K, González-Montero J. Consensus molecular subtypes of colorectal cancer in clinical practice: A translational approach. World J Clin Oncol 2021; 12(11): 1000-1008
- URL: https://www.wjgnet.com/2218-4333/full/v12/i11/1000.htm
- DOI: https://dx.doi.org/10.5306/wjco.v12.i11.1000