Review
Copyright ©2010 Baishideng Publishing Group Co.
World J Clin Oncol. Nov 10, 2010; 1(1): 35-40
Published online Nov 10, 2010. doi: 10.5306/wjco.v1.i1.35
Table 1 Cellular localization of procathepsin D/cathepsin D
FormLocalizationProcess
Pre-procathepsinRough endoplasmic reticulumSynthesis
ProcathepsinGolgi apparatusModification of oligosaccharides
ProcathepsinPrelysosomal compartmentsCleavage of the activation peptide
Single chain cathepsinLysosomesProteolytic processing, triming of oligosaccharides
Mature cathepsinLysosomes