Multiple roles of angiotensin in colorectal cancer

doi:10.5306/wjco.v3.i12.150

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Dec 10, 2012 (publication date) through Nov 25, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Dec 10, 2012; 3(12): 150-154
Published online Dec 10, 2012. doi: 10.5306/wjco.v3.i12.150

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Figure 1 Aniotensinogen is activated to become a bioactive form, angiotensin II by some enzymes, such as ACE. In angiotensin receptors (blue boxed), angiotensin II type 1 receptor is pro-tumoral; however, angiotensin II type 2 receptor is not definitive. Angiotensin 1-7, a degraded product of angiotensin IIactivates MAS1 receptor to provide inhibitory effects. Substances marked with yellow boxes are possible inhibitors for angiotensin effects.

Citation: Kuniyasu H. Multiple roles of angiotensin in colorectal cancer. World J Clin Oncol 2012; 3(12): 150-154
URL: https://www.wjgnet.com/2218-4333/full/v3/i12/150.htm
DOI: https://dx.doi.org/10.5306/wjco.v3.i12.150