Predictive value of peripheral blood systemic immune-inflammation index and blood cell ratio for gastrointestinal polyp burden in patients with Peutz-Jeghers syndrome

Figure 1 Scatter plots of systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio with polyp number. SII: Systemic immune-inflammation index; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio.

Figure 2 Receiver operating characteristic curves for systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio in the presence or absence of polyps in different locations. A: Small intestine; B: Stomach; C: Colorectum; D: Receiver operating characteristic curves for polyp burden in the presence or absence of intussusception. SII: Systemic immune-inflammation index; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio.

Figure 3 Grouping of Peutz-Jeghers syndrome patients based on the optimal cutoff. SII: Systemic immune-inflammation index; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio.

Figure 4 The relationship between high/low systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio groups and the number and diameter of small intestinal polyps. SII: Systemic immune-inflammation index; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio.

Figure 5  The distribution of malignant tumors in Peutz-Jeghers syndrome patients.

Figure 6  Cumulative risk of cancer in Peutz-Jeghers syndrome patients.

Figure 7 The predictive value of the combined application of systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio for Peutz-Jeghers syndrome polyp characteristics. A: Polyp diameter ≥ 25 mm; B: Polyp number ≥ 10. SII: Systemic immune-inflammation index; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; MLR: Monocyte-to-lymphocyte ratio.