Ipilimumab and Nivolumab induced steroid-refractory colitis treated with infliximab: A case report

Table 1 Labs at admission

Items	Data
WBC	20.39 × 109/L
Neutrophil	61%
Lymphocytes	6%
Monocytes	6%
Eosinophil	0%
Hemoglobin	9.9 mmol/L
Platelets	335 × 109/L
RDW	20%
Sodium	132 mmol/L
Potassium	2.8 mmol/L
Chloride	92 mmol/L
CO2	7 mmol/L
Creatinine	486.2 µmol/L
Calcium	2.3 mmol/L
Anion gap	33 mmol/L
Albumin	0.57 mmol/L
Phosphorous	3 mmol/L
AST	15 IU/L
ALT	26 IU/L
Total bilirubin	6.8 µmol/L
Alkaline phosphatase	110 IU/L
Magnesium	1.1 mmol/L

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; CO₂: Serum carbon dioxide; RDW: Red blood cell distribution width; WBC: White blood cell count.

Table 2 Infectious workup

Infectious workup
Clostridium difficile toxin B gene DNA PCR
Salmonella, shigella/enteroinvasive E coli, campylobacter, shiga toxin 1/2 NAAT
Cryptosporidium stool antigen, giardia stool antigen
Ova and parasite
Yersinia enterocolitica culture
Vibrio stool culture
Stool cultures
Influenza/respiratory synctial virus /rhinovirus/adenovirus/metapneumovirus
Blood and urine cultures
Cytomegalovirus colon biopsy DNA PCR
Herpes simplex virus 1/2 colon biopsy DNA PCR

NAAT: Nucleic acid amplification test; PCR: Polymerase chain reaction.