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©The Author(s) 2018.
World J Gastrointest Pathophysiol. Oct 25, 2018; 9(3): 63-72
Published online Oct 25, 2018. doi: 10.4291/wjgp.v9.i3.63
Published online Oct 25, 2018. doi: 10.4291/wjgp.v9.i3.63
Table 1 Diseases associated with oesophageal eosinophilia
| GORD |
| Eosinophilic gastrointestinal diseases |
| Atopy |
| Coeliac disease |
| Crohn’s disease |
| Oesophageal infections |
| Hypereosinophilic syndrome |
| Achalasia |
| Drug hypersensitivity |
| Vasculitis |
| Pemphigoid vegetans |
| Connective tissue disease |
| Graft-versus-host-disease |
| Oesophageal atresia |
Table 2 Diagnostic features of gastro-oesophageal reflux disease and eosinophilic oesophagitis
| GORD | EoE | |
| Endoscopic | Erosive oesophagitis | Trachealization |
| Peptic strictures | Felinization | |
| Hiatus hernia | Whitish exudates | |
| Barrett’s oesophagus | Longitudinal furrows | |
| Oedema | ||
| Diffuse oesophageal narrowing | ||
| Narrow-calibre oesophagus | ||
| Oesophageal lacerations | ||
| Loss of mucosal vascular pattern | ||
| Histological | Eosinophilia < 10/hpf | Eosinophilia ≥ 15/hpf |
| Eosinophilic microabscesses | ||
| Eosinophil degranulation | ||
| Basal cell hyperplasia | ||
| Papillary lengthening | ||
| Superficial layering of eosinophils | ||
| Extracellular eosinophil granules | ||
| Intracytoplasmic keratinocyte vacuolation | ||
| Dilated intracellular spaces | ||
| Lamina propria fibrosis | ||
| Positive intrasqamous IgG4 | ||
| Motor function | Non-specific | Non-specific |
- Citation: Wong S, Ruszkiewicz A, Holloway RH, Nguyen NQ. Gastro-oesophageal reflux disease and eosinophilic oesophagitis: What is the relationship? World J Gastrointest Pathophysiol 2018; 9(3): 63-72
- URL: https://www.wjgnet.com/2150-5330/full/v9/i3/63.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v9.i3.63