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©The Author(s) 2025.
World J Gastrointest Pathophysiol. Jun 22, 2025; 16(2): 107994
Published online Jun 22, 2025. doi: 10.4291/wjgp.v16.i2.107994
Published online Jun 22, 2025. doi: 10.4291/wjgp.v16.i2.107994
Table 1 Significance and strength of association for each risk factor of gastroesophageal reflux disease
| Factor | Continuous variables | Categorical variables | |||
| Spearman ‘rho’ | P value | Fischer’s test | Cramer’s v value | Strength of association | |
| Age | 0.573 | < 0.0011 | < 0.0011 | 0.646 | Strong |
| Body mass index | 0.749 | < 0.0011 | < 0.0011 | 0.745 | Strong |
| Smoking | - | < 0.0011 | 0.476 | Relatively strong | |
| Alcoholism | - | < 0.0011 | 0.434 | Relatively strong | |
| Sleep | 0.710 | < 0.0011 | < 0.0011 | 0.642 | Strong |
| Diet | 0.492 | < 0.0011 | < 0.0011 | 0.639 | Strong |
| Stress | 0.289 | < 0.0011 | < 0.0011 | 0.727 | Strong |
| Community2 | - | 0.129 | 0.0900 | Very weak | |
| Socio-economic status2 | - | 0.932 | 0.0465 | Very weak | |
Table 2 Coefficients of factors in the logistic regression model for gastroesophageal reflux disease
| Factor | Coefficient β |
| Age | 0.01123340 |
| Body mass index | 0.05075936 |
| Smoking | -0.01586711 |
| Alcoholism | -0.03592046 |
| Sleep | 0.09640941 |
| Diet | 0.00588875 |
| Stress | 0.03304126 |
Table 3 Gastroesophageal reflux disease Risk Scoring Scale (Gastroesophageal Reflux Disease Risk Scoring System)
| Factor | Parameter | Score |
| Age (years) | Less than 20 | 3 |
| 21-40 | 5 | |
| 41-60 | 8 | |
| 61-80 | 11 | |
| Greater than 81 | 13 | |
| Body mass index | Less than 18 | 3 |
| 18-22.9 | 7 | |
| 23-24.9 | 10 | |
| More than 25 | 13 | |
| Smoking | Non-smoker | 0 |
| Smoker < 5 pack years | 0.2 | |
| Smoker > 5 pack years | 0.4 | |
| Alcohol score | Non-alcoholic | 0 |
| 0–6 | 0·2 | |
| 7–12 | 1.4 | |
| Diet score | < 4 | 2 |
| 4–8 | 1.5 | |
| 8–12 | 1 | |
| > 12 | 0.5 | |
| Stress score | < 4.5 | 1 |
| 4.5–6 | 2 | |
| > 6 | 2.5 | |
| Sleep score | < 4 | 3 |
| 4–8 | 6 | |
| > 8 | 9 |
- Citation: Subramanian S, Sundararaju U, Rajakumar HK, Coimbatore Sathyabal V, Murugan A, Gnanavel P, Sathishkumar K. Development and validation of a risk prediction model for gastroesophageal reflux disease: Gastroesophageal Reflux Disease Risk Scoring System. World J Gastrointest Pathophysiol 2025; 16(2): 107994
- URL: https://www.wjgnet.com/2150-5330/full/v16/i2/107994.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v16.i2.107994
