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©The Author(s) 2025.
World J Gastrointest Pathophysiol. Jun 22, 2025; 16(2): 107994
Published online Jun 22, 2025. doi: 10.4291/wjgp.v16.i2.107994
Published online Jun 22, 2025. doi: 10.4291/wjgp.v16.i2.107994
Table 1 Significance and strength of association for each risk factor of gastroesophageal reflux disease
Factor | Continuous variables | Categorical variables | |||
Spearman ‘rho’ | P value | Fischer’s test | Cramer’s v value | Strength of association | |
Age | 0.573 | < 0.0011 | < 0.0011 | 0.646 | Strong |
Body mass index | 0.749 | < 0.0011 | < 0.0011 | 0.745 | Strong |
Smoking | - | < 0.0011 | 0.476 | Relatively strong | |
Alcoholism | - | < 0.0011 | 0.434 | Relatively strong | |
Sleep | 0.710 | < 0.0011 | < 0.0011 | 0.642 | Strong |
Diet | 0.492 | < 0.0011 | < 0.0011 | 0.639 | Strong |
Stress | 0.289 | < 0.0011 | < 0.0011 | 0.727 | Strong |
Community2 | - | 0.129 | 0.0900 | Very weak | |
Socio-economic status2 | - | 0.932 | 0.0465 | Very weak |
Table 2 Coefficients of factors in the logistic regression model for gastroesophageal reflux disease
Factor | Coefficient β |
Age | 0.01123340 |
Body mass index | 0.05075936 |
Smoking | -0.01586711 |
Alcoholism | -0.03592046 |
Sleep | 0.09640941 |
Diet | 0.00588875 |
Stress | 0.03304126 |
Table 3 Gastroesophageal reflux disease Risk Scoring Scale (Gastroesophageal Reflux Disease Risk Scoring System)
Factor | Parameter | Score |
Age (years) | Less than 20 | 3 |
21-40 | 5 | |
41-60 | 8 | |
61-80 | 11 | |
Greater than 81 | 13 | |
Body mass index | Less than 18 | 3 |
18-22.9 | 7 | |
23-24.9 | 10 | |
More than 25 | 13 | |
Smoking | Non-smoker | 0 |
Smoker < 5 pack years | 0.2 | |
Smoker > 5 pack years | 0.4 | |
Alcohol score | Non-alcoholic | 0 |
0–6 | 0·2 | |
7–12 | 1.4 | |
Diet score | < 4 | 2 |
4–8 | 1.5 | |
8–12 | 1 | |
> 12 | 0.5 | |
Stress score | < 4.5 | 1 |
4.5–6 | 2 | |
> 6 | 2.5 | |
Sleep score | < 4 | 3 |
4–8 | 6 | |
> 8 | 9 |
- Citation: Subramanian S, Sundararaju U, Rajakumar HK, Coimbatore Sathyabal V, Murugan A, Gnanavel P, Sathishkumar K. Development and validation of a risk prediction model for gastroesophageal reflux disease: Gastroesophageal Reflux Disease Risk Scoring System. World J Gastrointest Pathophysiol 2025; 16(2): 107994
- URL: https://www.wjgnet.com/2150-5330/full/v16/i2/107994.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v16.i2.107994