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©The Author(s) 2021.
World J Gastrointest Pathophysiol. May 22, 2021; 12(3): 51-58
Published online May 22, 2021. doi: 10.4291/wjgp.v12.i3.51
Published online May 22, 2021. doi: 10.4291/wjgp.v12.i3.51
Total (%) | Reactivation (%) | RR (95%CI) | P value | |
Number of patients (%) | 72 (100) | 23 (32) | ||
Gender (male) | 21 (29.2) | 7 (33.3) | 1.09 (0.37-3.23) | 0.871 |
Mean age, years (SD) | 56.3 (9.6) | 57.3 (9.2) | NA | 0.900 |
MELD, median (IqR) | 12 (14) | 12 (12) | NA | 0.712 |
Lymphocyte count, median (IqR) | 929 (808) | 929 (770) | NA | 0.471 |
CMV receptor IgG-negative | 5 (8.7) | 2 (40) | 0.68 (0.11-4.40) | 0.652 |
HCV | 46 (63.9) | 15 (32.6) | 1.09 (0.39-3.1) | 0.872 |
HBV | 5 (6.9) | 1 (20) | 0.51 (0.05-4.9) | 1.000 |
Hepatocarcinoma | 42 (58.3) | 14 (33.3) | 1.17 (0.42-3.2) | 0.765 |
Fulminant hepatitis | 2 (3) | 0 | NA | NA |
Diabetes mellitus | 24 (33.3) | 8 (33.3) | 1.1 (0.38-3.13) | 0.858 |
Renal failure | 8 (11.1) | 5 (62.5) | 4.26 (0.92-19.7) | 0.100 |
Re-transplant | 2 (3) | 0 | NA | NA |
CMV (%) | No CMV (%) | RR (95%CI) | P value | |
Number of patients (%) | 16/68 (23.5) | 52/68 (76.5%) | ||
CMV reactivation before transplantation | 7/16 (43.8) | 15/52 (28.8) | 1.91 (0.6-6.1) | 0.265 |
Quantitative PCR pre-transplant (IU/mL), mean (SD) | 2862 (5696) | 868 (2756) | NA | 0.154 |
Gender (male) | 4/16 (25) | 16/52 (30.8) | 0.75 (0.2-2.7) | 0.762 |
Mean age, years (SD) | 55 (10.3) | 57.3 (8) | NA | 0.373 |
MELD score, median (IqR) | 11 (4) | 12 (11) | NA | 0.254 |
Lymphocyte count, median (IqR) | 1101 (1109) | 918 (754) | NA | 0.580 |
Organ rejection | 3/16 (18.7) | 8/52 (15.3) | 1.27 (0.3-5.5) | 0.716 |
CMV-negative receptor | 3/16 (18.7) | 1/52 (1.9) | 11.7 (1.1-122.6) | 0.038 |
Hepatitis C infection | 9/16 (56.2) | 34/52 (65.4) | 0.7 (0.2-2.1) | 0.508 |
Hepatitis B infection | 1/16 (6.2) | 4/52 (7.7) | 0.8 (0.1-7.1) | 0.100 |
Hepatocarcinoma | 9/16 (56.2) | 30/52 (57.7) | 0.9 (0.3-2.9) | 0.919 |
Fulminant hepatitis | 0 | 1/52 (1.9) | NA | NA |
Diabetes mellitus | 6/16 (37.5) | 16/52 (30.8) | 1.3 (0.4-4.3) | 0.615 |
Renal failure | 2/7 (12.5) | 5/52 (9.6) | 1.3 (0.2-7.7) | 0.664 |
Re-transplantation | 1/16 (6.2) | 1/52 (1.9) | 3.4 (0.2-57.7) | 0.418 |
- Citation: Stadnik CMB, Caurio CFB, Rodrigues-Filho EM, Nedel WL, Cantisani GP, Zanotelli ML, Pasqualotto AC. Impact of cytomegalovirus reactivation just before liver transplantation: A prospective cohort study. World J Gastrointest Pathophysiol 2021; 12(3): 51-58
- URL: https://www.wjgnet.com/2150-5330/full/v12/i3/51.htm
- DOI: https://dx.doi.org/10.4291/wjgp.v12.i3.51