Gastro-oesophageal reflux disease and eosinophilic oesophagitis: What is the relationship?

Figure 1 Proposed pathogenesis of eosinophilic oesophagitis.

Figure 2 Endoscopic changes in patients with gastro-oesophageal reflux disease and eosinophilic oesophagitis. A: Erosive oesophagitis of gastro-oesophageal reflux disease; B: White exudates in eosinophilic oesophagitis (EoE); C: Mucosal rings or trachealization in EoE; D: Longitudinal furrows in EoE.

Figure 3 Histological specimen from the oesophagus (luminal aspect on left) of an eosinophilic oesophagitis patient showing marked oedema and numerous intraepithelial eosinophils in the oesophageal squamous mucosa, which are also seen in the superficial component of the mucosa.