Des-gamma-carboxy prothrombin and alpha-fetoprotein levels as biomarkers for hepatocellular carcinoma and their correlation with radiological characteristics

doi:10.4291/wjgp.v15.i1.90893

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Apr 22, 2024 (publication date) through Nov 28, 2024

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World Journal of Gastrointestinal Pathophysiology

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2150-5330

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Pathophysiol. Apr 22, 2024; 15(1): 90893
Published online Apr 22, 2024. doi: 10.4291/wjgp.v15.i1.90893

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Figure 1 Correlation of Des-gamma-carboxy prothrombin (DCP) and alpha fetoprotein in hepatocellular carcinoma patients using Spearman’s rank correlation analysis. P < 0.001. AFP: Alpha fetoprotein; PIVKA: protein induced by vitamin K absence-II also known as DCP.

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Figure 2 Receiver operating characteristic curve. A and B: Receiver operating characteristic curve comparing the values of two hepatocellular carcinoma biomarkers, des-gamma-carboxy-prothrombin, and alpha fetoprotein alone (A) or in combination (B) in a tumour size of 2 cm or more. Pivka: Protein induced by vitamin K absence-II [same as des-gamma-carboxy-prothrombin (DCP)]; afp: Alpha fetoprotein; combined: Combining DCP and AFP.

Citation: Qadeer MA, Abbas Z, Amjad S, Shahid B, Altaf A, Siyal M. Des-gamma-carboxy prothrombin and alpha-fetoprotein levels as biomarkers for hepatocellular carcinoma and their correlation with radiological characteristics. World J Gastrointest Pathophysiol 2024; 15(1): 90893
URL: https://www.wjgnet.com/2150-5330/full/v15/i1/90893.htm
DOI: https://dx.doi.org/10.4291/wjgp.v15.i1.90893