Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience

Table 1 Characteristics of the patients involved in this study

Characteristics	Value
Demographics
Mean age (yr)	65
Age range (yr)	52-79
Male/female	5/1
Location of primary tumor
Oropharynx	6
Metastatic loco-regional nodes	11
Radiation therapy technique	IMRT
Dose (Gy)	66-70
Fractions	32
Outcome
Alive with disease	3
Dead of disease	2
No evidence of disease	1

Table 2 Apparent diffusion coefficient metric values for human papillomavirus negative head and neck squamous cell carcinoma patients who were classified based on survival as dead of disease, alive with disease and no evidence of disease before, during and post- radiotherapy

MRI	DOD ADC mean (× 10-3 mm2/s)		AWD ADC mean (× 10-3 mm2/s)		NED ADC mean (× 10-3 mm2/s)
	Primary	Node	Primary	Node	Primary	Node
Pre-Tx	1.51 ± 0.36	1.43 ± 0.58	1.66 ± 0.41	1.26 ± 0.19	0.85 ± 0.27	0.86 ± 0.20
During Tx (2-3 wk)	1.92 ± 0.33	1.54 ± 0.11	2.12 ± 0.38	1.41 ± 0.38	1.49 ± 0.13	1.39 ± 0.08
Post-Tx	No primary	0.98 ± 0.29	No primary	1.93 ± 0.22	No primary	No node

MRI: Magnetic resonance imaging; ADC: Apparent diffusion coefficient; AWD: Alive with disease; DOC: Dead of other causes; DOD: Dead of disease; NED: No evidence of disease.