Value of serial magnetic resonance imaging in the assessment of brain metastases volume control during stereotactic radiosurgery

Table 1 Patient population and primary cancer types

No. ofpatients	Gender	Age (yr)	Primary cancer type	No. of lesions, (%)
11	7 men - 4 women	50-70	Non-small cell lung carcinoma	19 (36)
9	1 men - 8 women	32-60	Breast carcinoma	16 (29)
7	5 men - 2 women	55-77	Renal cell carcinoma	9 (16)
4	1 men - 3 women	32-65	Melanoma	10 (19)

Table 2 Primary cancer types and effective time point for magnetic resonance imaging follow-up to provide useful information for the treatment decision

Primary cancer type	No. of lesions	%4	Reduced in size at 6 wk1	%4	Pseudo-progression (9 wk)2	%4	True-progression (12 mo)3	%4
Non-small cell lung carcinoma	19	36	12	22	8	15	1	2
Breast carcinoma	16	29	11	20	7	13	4	7
Renal cell carcinoma	9	16	1	2	0	0	6	11
Melanoma	10	19	1	2	0	0	8	15
Total	54	100	25	46	15	28	19	35

¹Number of lesions reduced in size at 6-wk follow-up;

²Number of lesions that presented a transient volume growth (pseudo-progression) at 9-wk follow-up;

³Number of lesions that presented final volume growth (true-progression) at 12-mo follow-up;

⁴Percentage of lesions computed over the total number of lesions (n = 54).