Value of acoustic radiation force impulse elastography for the assessment of ascites syndrome

Table 1 Characteristics of the patients

Parameter	All patients	Cirrhotic patients	Non-cirrhotic patients
Mean age (yr)	58.8 ± 13.1	58.6 ± 12.1	57.4 ± 15.3
Sex, n (%)
Female	61 (39.8)	50 (43.5)	7 (24.1)
Male	92 (60.2)	65 (56.5)	22 (75.9)
Classification of ascites, n (%)
Grade 1	70 (45.7)	53 (46.1)	14 (48.3)
Grade 2	50 (32.7)	36 (31.3)	10 (34.4)
Grade 3	33 (21.5)	26 (22.6)	5 (17.3)
Mean ARFI values (range, m/s)	1.60 ± 0.66 (0.83-4.87)	3.04 ± 0.70 (1.62-4.87)	1.45 ± 0.59 (0.83-3.94)
Mean AST (U/L) (normal value = 5-34 U/L)	83.5 ± 72.8	95.1 ± 76.2	47.2 ± 43.4
Mean ALT (U/L) (normal value = 10-35 U/L)	47.7 ± 37.1	49.3 ± 33.5	47.1 ± 50
Mean total bilirubin (mg/dL) (normal value = 0.2-1 mg/dL)	3.25 ± 3.78	3.29 ± 2.80	3.41 ± 6.55
Mean total protein (g/dL) (normal value = 5.6-8 g/dL)	6.2 ± 1.2	6.5 ± 1.1	6 ± 1.2
Mean albumin (g/dL) (normal value = 3.5-5 g/dL)	3.02 ± 0.67	2.95 ± 0.66	3.38 ± 0.68
Mean prothrombin index time (%) (normal value > 75%)	70.1 ± 14.4	65.7 ± 16	86.3 ± 15.9
Mean cholinesterase value (U/L) (normal value = 4500-8000 U/L)	3252.9 ± 1743.1	2810.2 ± 1414.3	5220.3 ± 1977.2

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ARFI: Acoustic radiation force impulse.

Table 2 Predictive value of acoustic radiation force impulse elastography for the cirrhotic etiology of ascites (%)

Cut-off	Se	Sp	PPV	NPV	Accuracy
1.8 m/s	98.1	86.2	96.4	92.5	95.6
1.9 m/s	97.2	86.2	96.2	89.2	94.9
2 m/s	94.5	86.2	96.2	80.6	92.8

Se: Sensitivity; Sp: Specificity; PPV: Positive predictive value; NPV: Negative predictive value.