Singh P, Agrawal K, Rahman A, Singhal T, Parida GK, Gnanasegaran G. Incidence of exclusive extrapelvic skeletal metastasis in prostate carcinoma on bone scintigraphy. World J Radiol 2024; 16(7): 265-273 [PMID: 39086611 DOI: 10.4329/wjr.v16.i7.265]
Corresponding Author of This Article
Kanhaiyalal Agrawal, MBBS, MD, Additional Professor, Department of Nuclear Medicine, All India Institute of Medical Sciences, Sijua, Dumuduma, Bhubaneshwar 751019, Odisha, India. nucmed_kanhaiyalal@aiimsbhubaneswar.edu.in
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Observational Study
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World J Radiol. Jul 28, 2024; 16(7): 265-273 Published online Jul 28, 2024. doi: 10.4329/wjr.v16.i7.265
Table 1 Planar bone scintigraphy findings
Pattern of uptake on bone scan
Number of patients among, n = 150
No abnormal increased osteoblastic activity
13
Increased uptake with pattern typical of degenerative changes/benign uptake
24
Multifocal increased uptake typical for metastatic disease
30
Indeterminate or suspicious for metastatic uptake where SPECT-CT was performed
83
Table 2 Single photon emission computed tomography-computed tomography findings
Lesion
Number of patients among, n = 83
Benign
31
Metastatic
51
Indeterminate
1
Table 3 Location of uptake and characterization in patients with exclusive extrapelvic uptake
Site of uptake
Benign
Metastatic
Indeterminate
Vertebra
41
3
0
Ribs
7
0
0
Sternum and manubriosternal region
2
0
0
Skull
2
0
1
Table 4 Single photon emission computed tomography-computed tomography characterization of isolated extrapelvic uptake
Serial No.
Age in years
Site of uptake
SPECT-CT findings
Final diagnosis
1
67
Left 1st rib
Arthritis
Benign
2
83
Right 5th rib
Fibrous dysplasia
Benign
3
66
Right 6th rib
Fracture line likely post traumatic
Benign
4
63
Right 11th rib
Fracture line likely post traumatic
Benign
5
72
Right 6th rib
Fracture line likely post traumatic
Benign
6
60
Sternum
Manubriosternal joint
Benign
7
76
Right parietal bone
Subtle sclerosis not typical for metastatic disease
Indeterminate
Table 5 Site of metastatic disease on bone scintigraphy
Site
Number of patients
Super-scan
10
Pelvic bones
68
Vertebrae
63
Ribs
55
Sternum
42
Femur
41
Scapula
41
Skull
32
Clavicle
29
Humerus
23
Others
7 (4 tibia, 2 forearm bones, 1 maxilla)
Citation: Singh P, Agrawal K, Rahman A, Singhal T, Parida GK, Gnanasegaran G. Incidence of exclusive extrapelvic skeletal metastasis in prostate carcinoma on bone scintigraphy. World J Radiol 2024; 16(7): 265-273