Prospective Study
Copyright ©The Author(s) 2022.
World J Radiol. Jun 28, 2022; 14(6): 165-176
Published online Jun 28, 2022. doi: 10.4329/wjr.v14.i6.165
Table 1 Comparison of demographic, clinical and preoperative radiological parameters between patients with and without clinically relevant postoperative pancreatic fistula
Parameter
CR-POPF, n = 18
No CR-POPF, n = 43
P value
Age in yr, mean ± SD53.7 ± 10.854.7 ± 11.50.746
Sex, n (%)
Male10 (55.6)28 (65.1)0.567
Female8 (44.4)15 (34.9)
BMI in kg/m2, mean ± SD21.1 ± 4.420.1 ± 3.90.388
Weight loss, n (%)15 (83.3)32 (74.4)0.525
Comorbidities, n (%)11 (61.1)22 (51.2)0.578
Hemoglobin in gm%, mean ± SD10.7 ± 1.410.8 ± 1.50.735
Preoperative serum bilirubin (mg/dL), median (IQR)2 (1.8-6)3 (1-7)0.848
Preoperative biliary drainage, n (%)10 (55.6)22 (51.2)0.786
Pancreatic attenuation index, mean ± SD0.8 ± 0.20.8 ± 0.20.741
Pancreatic enhancement ratio, mean ± SD0.6 ± 0.20.8 ± 0.40.006
Table 2 Correlation between preoperative radiological indices and histopathological pancreatic neck fat fraction and fibrosis

Pancreatic attenuation index
Pancreatic enhancement ratio
Pancreatic fat fraction
Fibrosis score
Pancreatic attenuation index--0.27 a 0.21-0.20
Pancreatic enhancement ratio-0.27a --0.100.50 b
Pancreatic fat fraction0.21 -0.10--0.12
Fibrosis score-0.20 0.50 b -0.12 -
Table 3 Comparison of perioperative and pathological parameters between patients with and without clinically relevant postoperative pancreatic fistula
Parameter
CR-POPF, n = 18
No CR-POPF,n = 43
P value
Operative time in min, mean ± SD521.9 ± 123463.9 ± 101.20.275
Blood loss in mL, median (IQR)550 (350-725)475 (350-800)0.830
Intraoperative blood transfusion, n (%)6 (33.3)17 (39.5)0.775
Pancreatic texture, n (%)
Firm1 (5.6)20 (47.6)0.002
Soft17 (94.4)22 (52.4)
Pancreatic duct size in mm, mean ± SD2.8 ± 1.13.4 ± 1.60.169
Surgical approach, n (%)
Open9 (50)24 (55.8)
Laparoscopic6 (33.3)12 (27.9)
Robot assisted3 (16.7)7 (16.3)0.927
Delayed gastric emptying, n (%)15 (83.3)13 (30.2)< 0.001
Postpancreatectomy hemorrhage, n (%)3 (16.7)4 (9.3)0.662
Intra-abdominal abscess, n (%)9 (50)1 (2.3)< 0.001
Hospital stay in d, mean ± SD26.8 ± 13.99.6 ±.60.001
Pathology, n (%)
Malignant17 (94.4)35 (81.4)
Benign1 (5.6)8 (18.6)0.259
Fat fraction, n (%)
Absent 6 (33.3)20 (46.5)
Mild9 (50.0)17 (39.6)0.669
Moderate3 (16.7)6 (13.9)
Fibrosis score, n (%)
Weak16 (88.9)27 (62.8)
Heavy2 (11.1)16 (37.2)0.063