Discrepancies in the clinical and radiological profiles of COVID-19: A case-based discussion and review of literature

Table 1 Coronavirus disease-19 Reporting and Data System category of computed tomography reporting and the level of suspicion for coronavirus disease-19[41]

Category	Level of suspicion	Summary of CT observation and interpretation
CO-RADS 0	Cannot interpret	Due to technically insufficient CT scan
CO-RADS 1	Very low	Normal CT chest or non-infectious CT chest
CO-RADS 2	Low	Typical for other infections like lobar consolidation
CO-RADS 3	Equivocal	Features compatible with COVID-19 & other infections
CO-RADS 4	High	Suspicious CT features of COVID-19
CO-RADS 5	Very high	Typical CT features of COVID-19
CO-RADS 6	Proven (RT-PCR)	RT-PCT positive for SARS-CoV-2 RNA

CT: Computed tomography; CO-RADS: Coronavirus disease-19 Reporting and Data System; COVID-19: Coronavirus disease-19; SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; RT-PCR: Reverse transcriptase polymerase chain reaction.

Table 2 Extent of lung involvement and the corresponding computed tomography scores[47,49]

CT score	Extent of lung involvement
Score 0	No lung involvement
Score 1	< 5% lung involvement
Score 2	5%-25% lung involvement
Score 3	26%-50% lung involvement
Score 4	51%-75% lung involvement

CT: Computed tomography.

Table 3 Efficacy of reverse transcriptase polymerase chain reaction, chest X-ray, computed tomography chest, and lung ultrasound in the diagnosis is of coronavirus disease-19 [16,24,43,44,69]

	Sensitivity	Specificity	PPV	NPV
RT-PCR	87.0%	97.0%	98.0%	80.0%
CXR	89.0%	60.6%	87.9%	63.1%
CT-chest	90.0%-90.7%	78.8%-91.0%	86.4%-89.0%	85.1%-92.0%
Lung US	89.0%	59.0%	47.0%	93.0%

CT: Computed tomography; RT-PCR: Reverse transcriptase polymerase chain reaction; CXR: Chest X-ray; US: Ultrasonography; PPV: Positive predictive value; NPV: Negative predictive value.