Positron emission tomography/computed tomography imaging appearance of benign and classic “do not touch” osseous lesions

Table 1 Patient characteristics by lesion type

Lesion type	Mean patient age (yr)	Range patient age (yr)	Male (%)
Benign cystic lesions (n = 42)	63.2	36-92	69.0
Hemangioma (n = 29)	68.5	47-88	55.2
Bone infarct (n = 16)	58.7	33-74	62.5
Bone island (n = 56)	63.0	37-90	50.0
Enchondroma (n = 45)	64.6	52-84	46.7%
Fibrous dysplasia (n = 26)	56.1	28-86	76.9
Osteochondroma (n = 6)	61.3	43-80	100.0
Paget’s disease of bone (n = 20)	73.4	59-86	80.0
Insufficiency fracture (n = 32)	69.1	47-89	6.3
Osteomyelitis (n = 15)	62.8	32-83	73.3

Benign cystic lesions: Subchondral cysts, bone cysts, herniation pits, and geodes.

Table 2 18-F-fluorodeoxyglucose positron emission tomography/computed tomography standardized uptake value by lesion type

Lesion type	Range of the max SUV	Median (interquartile range) of the max SUV	Mean SUV (SD)	Proportion with max SUV > 3.0 (%)	Maximum SUV/mean blood Pool SUV range	Maximum SUV /mean blood pool SUV median (interquartile range)	Proportion of lesions with maximum SUV > mean blood pool (maximum SUV/mean blood pool SUV > 1.0) (%)
Benign cystic lesions (n = 42)	0.68-6.5	1.90 (1.34-3.27)	1.38 (0.86)	28.6	0.5-3.74	1.29 (0.76-1.94)	64.3
Hemangioma (n = 29)	0.95-2.88	1.86 (1.38-2.00)	1.14 (0.30)	0	0.49-1.42	0.88 (0.78-1.05)	34.5
Bone infarct (n = 16)	0.37-3.44	1.27 (0.95-1.80)	0.80 (0.54)	12.5	0.15-2.18	0.75 (0.57-1.08)	37.5
Bone island (n = 56)	0.26-3.29	1.18 (0.91-1.73)	1.04 (0.52)	1.8	0.13-2.28	0.69 (0.53-0.98)	25.0
Enchondroma (n = 45)	0.46-2.69	1.49 (1.05-1.98)	0.93 (0.43)	0.0	0.25-1.72	0.90 (0.58-1.15)	42.2
Fibrous dysplasia (n = 26)	0.78-18.63	2.07 (1.56-3.04)	1.80 (1.40)	30.8	0.49-8.87	1.35 (0.89-1.93)	69.2
Osteochondroma (n = 6)	1.11-2.56	1.71 (1.25-1.93)	0.89 (0.09)	0	0.64-1.50	0.82 (0.78-1.02)	33.3
Paget’s disease of bone (n = 20)	0.93-5.65	2.59 (1.66-3.79)	1.77 (0.82)	45.0	0.70-4.30	1.45 (1.10-2.23)	75.0
Insufficiency fracture (n = 32)	1.06-12.97	2.95 (2.05-4.09)	1.82 (0.68)	46.9	0.64-5.43	1.76 (1.33-2.25)	90.6
Osteomyelitis (n = 15)	2.57-12.64	6.40 (3.99-8.63)	3.77 (1.31)	80.0	1.07-9.34	4.88 (2.34-5.88)	100

Benign cystic lesions: Subchondral cysts, bone cysts, herniation pits, and geodes. SUV: Standardized uptake value.