Progress in image-guided radiotherapy for the treatment of non-small cell lung cancer

Table 1 Summary of important data of advantage of image-guided radiotherapy in radiotherapy

Ref.	Published date	Authors	Highlights of detailed data
[21]	2003	Remouchamps et al	The use of mDIBH reduced the mean percentage of both lungs receiving more than 20 Gy from 20.4% to 15.2% (P < 0.00007)
[22]	2015	Muralidhar et al	The mean difference of right lung volume receiving more than 20 Gy of the dose was from 1% to -98 % (IGRT < 0.24556)
[26]	2003	Hof et al	In the craniocaudal direction the mean tumor movement was 5.1 mm , in the ventrodorsal direction 3.1 mm, and in the lateraldirection 2.6 mm
[31]	2017	Tan et al	The errors of image-guided registration using 4D-CBCT and 3D-CBCT on the X, Y, Z axes, and 3D space were 0.80 ± 0.21 mm and 1.08 ± 0.25 mm, 2.02 ± 0.46 mm and 3.30 ± 0.53 mm, 0.52 ± 0.16 mm and 0.85 ± 0.24 mm, and 2.25 ± 0.44 mm and 3.59 ± 0.48 mm (all P < 0.001), respectively
[32]	2017	Ehrbar et al	Compared with the 4D dose calculations, the mid-ventilation and single-phase tracking overestimated the target mean dose (2.3% and 1.3%), respectively
[34]	2016	Garibaldi	The PTV margins used to compensate for residual tumor localization errors were 3.1, 3.5 and 3.3 mm in the LR, SI and AP directions, respectively
[7]	2016	Wang et al	Position errors after correction in Left–right, Anterior–posterior and Cranial–caudal were 0.22 cm, 0.16 cm and 0.19 cm, respectively
[36]	2016	Ariyaratne et al	Under the use of IGRT, the population mean setup error was 0.01 cm (left–right), 0.05 cm (supero-inferior) and 0.13 cm (antero-posterior)

mDIBH: Moderate deep inspiration breath hold; IGRT: Image-guided radiotherapy; PTV: Planned target volume.