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Metcalf T, Paulson AE, Sborov KD, Moore-Lotridge SN, Schoenecker JG, Mencio GA, Martus JE, Louer CR. The Thoracolumbar Injury Classification and Severity Score Appropriately Predicts Treatment in Children Aged 10 and Under. Spine (Phila Pa 1976) 2025; 50:832-840. [PMID: 39262216 DOI: 10.1097/brs.0000000000005155] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/25/2024] [Accepted: 08/30/2024] [Indexed: 09/13/2024]
Abstract
STUDY DESIGN A retrospective cohort study. OBJECTIVE This study aims to assess the validity of the Thoracolumbar Injury Classification and Severity Score (TLICS) in patients ≤10 years old. SUMMARY OF BACKGROUND DATA TLICS is a validated measure developed to help facilitate clinical decision-making regarding thoracolumbar spinal trauma in adults. Studies examining the utility of TLICS in children skew toward older pediatric patients, where the spine's biomechanical properties are more similar to adults. Due to differences in a preadolescent spine compared with a more mature, adolescent spine, it is unclear if TLICS can be applied to younger patients. METHODS A single-center spine trauma registry was queried for patients ≤10 with an acute, traumatic thoracolumbar fracture treated at a level-1 pediatric trauma center between 2006 and 2020. Test characteristics and receiver-operator curve were used to evaluate TLICS based on TLICS <4 recommedning nonsurgical treatment and TLICS >4 recommending surgery. RESULTS We identified 94 patients with traumatic thoracolumbar fractures (surgical=20; nonsurgical=74). Despite TLICS-suggested operative management in 28 patients with TLICS >4, nine (32.1%) were initially treated nonoperatively. All patients who deviated from TLICS-suggested treatment had flexion-distraction injuries (FDI). Sensitivity, specificity, positive predictive value, and negative predictive value were 100%, 89.2%, 70.4%, and 100%, respectively. The receiver operating characteristic curve demonstrated a strong diagnostic ability of TLICS in predicting the need for surgery (area under the curve: 0.97, F1-score: 0.86). CONCLUSION TLICS score <4 showed strong validity and is highly specific in predicting non-operative management for patients ≤10 years old with thoracolumbar fractures. However, TLICS >4 has more limited specificity in indicating the necessity for surgical intervention, as many FDIs were successfully treated without surgery. Additional factors other than TLICS score may need to be considered for these more severe injuries to optimize management in this age group.
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Affiliation(s)
- Tyler Metcalf
- Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN
| | - Ambika E Paulson
- Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN
| | - Katherine D Sborov
- Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN
| | - Stephanie N Moore-Lotridge
- Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN
- Vanderbilt Center for Bone Biology, Vanderbilt University Medical Center, Nashville, TN
| | - Jonathan G Schoenecker
- Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN
- Vanderbilt Center for Bone Biology, Vanderbilt University Medical Center, Nashville, TN
- Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN
- Department of Pharmacology, Vanderbilt University, Nashville, TN
- Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN
| | - Gregory A Mencio
- Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN
| | - Jeffrey E Martus
- Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN
| | - Craig R Louer
- Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN
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Aly MM, Abdelaziz M, Alfaisal FA, Alrumian RA, Espinoza XAS, Gutiérrez-González R, García TK, Al Fattani A, Almohamady W, Al-Shoaibi AM. Multicenter External Validation of the Accuracy of Computed Tomography Criteria for Detecting Thoracolumbar Posterior Ligamentous Complex Injury. Neurosurgery 2025; 96:1236-1248. [PMID: 39636120 DOI: 10.1227/neu.0000000000003263] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/30/2024] [Accepted: 09/06/2024] [Indexed: 12/07/2024] Open
Abstract
BACKGROUND AND OBJECTIVE Recent studies have proposed computed tomography (CT) criteria for posterior ligamentous complex (PLC) injury: disrupted if ≥2 CT findings, indeterminate if single finding, and intact if 0 CT findings. The study aims to validate the CT criteria for PLC injury externally. METHODS Three level 1 trauma centers enrolled 614 consecutive patients with acute thoracolumbar fractures (T1-L5) who received CT and MRI. Three reviewers from each center assessed CT for facet joint malalignment, horizontal laminar fracture, spinous process fracture, and interspinous widening and MRI for disrupted PLC, defined as black stripe discontinuity. The primary outcome is the diagnostic accuracy of CT criteria (0, 1, ≥2 findings) in detecting disrupted PLC on MRI using all CT readings. A subgroup analysis was performed for each participating center and reviewer. The inter-reader agreement on PLC status on MRI and CT criteria was assessed using Fleiss Kappa ( k ). RESULTS The positive predictive value for PLC injury was 0 findings 3%, single positive CT 43%, and ≥2 CT findings in 94%. The accuracy measures were consistent across various centers and reviewers. The area under the curve for ≥1 CT finding in detecting PLC injury ranged from 90% to 97%, indicating excellent discrimination for all centers. The inter-reader k on PLC status by MRI and overall CT findings was substantial ( k > 0.60). CONCLUSION This study externally validates the previously proposed CT criteria for PLC injury. A total of ≥2 positive CT findings or 0 CT findings can be used as criteria for a disrupted PLC (B-type injury) or intact PLC (A-type injuries), respectively, without added MRI. A single CT finding implies indeterminate PLC status and the need for further MRI assessment. The CT criteria will potentially guide MRI indications and treatment decisions for neurologically intact thoracolumbar burst fractures.
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Affiliation(s)
- Mohamed M Aly
- Department of Neurosurgery, Mansoura University, Mansoura , Egypt
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh , Saudi Arabia
- Current Affiliation: Department of Neurosurgery, Prince Mohamed Ben Abdulaziz Hospital, Riyadh , Saudi Arabia
| | - Mohamed Abdelaziz
- Department of Orthopedic, King Saud Medical City, Riyadh , Saudi Arabia
- Department of Orthopedic, Mansoura University, Mansoura , Egypt
| | - Faisal A Alfaisal
- Department of Diagnostic Radiology, King Saud Medical City, Riyadh , Saudi Arabia
| | | | | | - Raquel Gutiérrez-González
- Department of Neurosurgery, University Hospital Puerta de Hierro Majadahonda, Madrid , Spain
- Department of Surgery, Faculty of Medicine, Autonomous University of Madrid, Madrid , Spain
| | - Teresa Kalantari García
- Department of Neurosurgery, University Hospital Puerta de Hierro Majadahonda, Madrid , Spain
| | - Areej Al Fattani
- Department of Biostatistics Epidemiology and Scientific Computing, King Faisal Specialist Hospital and Research Hospital, Riyadh , Saudi Arabia
| | - Waleed Almohamady
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh , Saudi Arabia
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Sarathy D, Lucke-Wold B, Chan JL. Commentary: Multicenter External Validation of the Accuracy of Computed Tomography Criteria for Detecting Thoracolumbar Posterior Ligamentous Complex Injury. Neurosurgery 2025; 96:e125-e126. [PMID: 39636123 DOI: 10.1227/neu.0000000000003265] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/21/2024] [Accepted: 09/25/2024] [Indexed: 12/07/2024] Open
Affiliation(s)
- Danyas Sarathy
- Department of Neurosurgery, University of Florida, Gainesville , Florida , USA
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Dagdia L, Kulkarni SS, Gadekar GN. Short-Segment Fixation in the Management of Thoracolumbar Burst Fractures - A Meta -analysis. J Orthop Case Rep 2025; 15:248-255. [PMID: 40351651 PMCID: PMC12064244 DOI: 10.13107/jocr.2025.v15.i05.5624] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/16/2025] [Revised: 03/10/2025] [Indexed: 05/14/2025] Open
Abstract
Introduction Short- segment fixation is being increasingly used to minimiz e the number of fixation levels in thoracolumbar burst fractures (TLBFs). This study aims to analyze the radiological, functional, and neurological outcomes of short-segment fixation in TLBF. Materials and Methods A meta-analysis was conducted through a web search on PubMed with the following keywords; thoracolumbar injury, burst fracture, and short- segment fixation. Scientific papers written in English from January 2001 to April 2024 were screened. PubMed search with the keywords revealed 183 articles which were thoroughly reviewed by all the authors. Of these, 11 studies satisfying the inclusion criteria describing short- segment fixation in TLBF s were included in this study. The minimum follow-up duration in each study was 12 months. The appropriate meta-analysis was carried out, and the forest plot for a single group which accounts for interstudy variation and provides a more conservative effect than the fixed effect model. Potential sources of heterogeneity were assessed using the standard chi-square test. In addition, the statistic I2 was used to investigate heterogeneity by examining the extent of inconsistency across the study results. A sensitivity analysis was carried out to assess the robustness of the results of the meta-analysis. Where heterogeneity was present between the studies, differences in study design were examined. All analyses were performed using online free meta-analysis software (https://metaanalysisonline.com). Results The results of this meta-analysis suggested that studies with an added intermediate screw at the level of fractured vertebra showed a better radiological appearance at the final follow- up as compared to traditional short-segment instrumentation. However, clinical outcomes showed no significant difference. A post-surgery neurological improvement was noted in all the studies except those with a complete pre-operative neurological deficit. Conclusion Short-segment instrumentation with intermediate screw fixation is a safe and effective method with excellent radiological and clinical outcomes with very low rates of failure while treating unstable TLBFs, where as traditional short-segment posterior fixation can lead to progressive loss of kyphosis correction with higher implant failure rate in patients with unstable fractures.
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Affiliation(s)
- Laxmikant Dagdia
- Department of Orthopaedics, MGM Medical College & Hospital, Chharatrpati Sambhajinagar, Aurangabad, India
| | - Saurabh Shrikant Kulkarni
- Department of Orthopaedics, MGM Medical College & Hospital, Chharatrpati Sambhajinagar, Aurangabad, India
| | - Girish N. Gadekar
- Department of Orthopaedics, MGM Medical College & Hospital, Chharatrpati Sambhajinagar, Aurangabad, India
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Pidd KT, Sadauskas D, Tomatis V, Knight EJ. Which is the Superior Thoracolumbar Injury Classification Tool? TLICS Versus AOSpine 2013: A Systematic Review. Global Spine J 2025; 15:2536-2546. [PMID: 39722528 PMCID: PMC11670229 DOI: 10.1177/21925682241311303] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/26/2024] [Revised: 12/05/2024] [Accepted: 12/17/2024] [Indexed: 12/28/2024] Open
Abstract
Study DesignSystematic Literature Review.ObjectivesTo address whether TLICS or AOSpine is best used in clinical practice through assessment of interobserver and intraobserver reliability, agreement, and imaging modality performance.MethodsThis systematic literature review was reported in accordance with PRISMA 2020 guidelines. Articles were included based on meeting eligibility criteria: studies evaluating TLICS, AOSpine, and/or TL AOSIS through reliability, agreement, or imaging modality performance with adult patients (≥18) suffering from traumatic thoracolumbar fractures. Articles were acquired in April 2023 from Medline, CINAHL, and Scopus. Risk of bias was assessed through a modified COSMIN checklist. Tabulated results were separated by classification tool (TLICS or AOSpine/TL AOSIS) and reliability, agreement, or imaging modality results.ResultsTwenty-one studies were included in the final review. Interobserver and intraobserver AOSpine morphology reliability was on average superior to TLICS. Increased familiarity with the tool positively influenced both AOSpine and TLICS performance. For surgical treatment recommendation, AOSpine differentiated between stable and unstable burst fractures and guided clinician's more accurately than TLICS. Regarding conservative treatment, both TLICS and AOSpine reported similar clinical accuracy. TLICS performed significantly better when MRI was incorporated compared to CT alone. CT was sufficient as an imaging modality for AOSpine/TL AOSIS performance.ConclusionsAOSpine outperformed TLICS in surgical reliability, agreement and did not require additional MRI imaging to improve accuracy. Limitations of evidence include low quality of available studies and significant heterogeneity in patient and observer number. Future prospective multicentre research is recommended. This study was not funded and not registered on PROSPERO.
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Affiliation(s)
- Kristina T. Pidd
- School of Medicine, Flinders University, Adelaide, SA, Australia
| | - David Sadauskas
- School of Medicine, Flinders University, Adelaide, SA, Australia
| | - Vanesa Tomatis
- Department of Neurosurgery, Flinders Medical Centre, Adelaide, SA, Australia
| | - Ema J. Knight
- Department of Neurosurgery, Flinders Medical Centre, Adelaide, SA, Australia
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Scherer J, Joaquim A, Vaccaro A, Kanna R, El-Sharkawi M, Takahata M, Aly MM, Camino-Willhuber G, Spiegl U, Oner C, Canseco JA, Yurac R, Benneker LM, Popescu EC, Bransford R, Chhabra HS, Kandziora F, Neva MH, Schnake KJ. AO Spine-DGOU Osteoporotic Fracture Classification System: Internal Validation by the AO Spine Knowledge Forum Trauma. Global Spine J 2025; 15:2152-2157. [PMID: 39327898 PMCID: PMC11559773 DOI: 10.1177/21925682241288187] [Citation(s) in RCA: 2] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 09/28/2024] Open
Abstract
Study DesignCross-sectional survey.ObjectivesInjury classifications are important tools to identify fracture patterns, guide treatment-decisions and aid to identify optimal treatment plans. The AO Spine-DGOU Osteoporotic Fracture (OF) classification system was developed, and the aim of this study was to assess the reliability of this new classification system.Methods23 Members of the AO Spine Knowledge Forum Trauma participated in the validation process. Participants were asked to rate 33 cases according to the OF classification at 2 time points, 4 weeks apart (assessment 1 and 2). The kappa statistic (κ) was calculated to assess inter-observer reliability and intra-rater reproducibility. The gold master key for each case was determined by approval of at least 5 out of 7 members of the DGOU.ResultsA total of 1386 ratings (21 raters) were performed. The overall inter-rater agreement was moderate with a combined kappa statistic for the OF classification of 0.496 in assessment 1 and 0.482 in assessment 2. The combined percentage of correct ratings (compared to gold-standard) in assessment 1 was 71.4% and 67.4% in assessment 2. The average intra-rater reproducibility was substantial (κ = 0.74, median 0.76, range 0.55 to 1.00, SD 0.13) for the assessed fracture types.ConclusionsThe assessed overall inter-rater reliability was moderate and substantial in some instances. The average intra-rater reproducibility is substantial. It seems that appropriate training of the classification system can enhance inter- and intra-rater reliability.
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Affiliation(s)
- Julian Scherer
- General Medicine & Global Health (GMGH), Department of Medicine and Orthopaedic Research Unit (ORU), Division of Orthopaedic Surgery, Faculty of Health Sciences, University of Cape Town, South Africa
- Department of Traumatology, University Hospital of Zurich, Zürich, Switzerland
| | - Andrei Joaquim
- Neurosurgery Division, Department of Neurology, State University of Campinas, Campinas-Sao Paulo, Brazil
| | - Alex Vaccaro
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Rishi Kanna
- Spine Department of Orthopaedics and Spine Surgery, Ganga Hospital, Coimbatore, India
| | - Mohammad El-Sharkawi
- Department of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt
| | - Masahiko Takahata
- Department of Orthopaedic Surgery, Dokkyo Medical University School of Medicine, Soka, Japan
| | - Mohamed M. Aly
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabi
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt
| | | | - Ulrich Spiegl
- Klinik für Unfallchirurgie und Orthopädie, Klinik München Harlaching, München, Germany
| | - Cumhur Oner
- Department of Orthopaedics, University Medical Centers, Utrecht, the Netherlands
| | - Jose A. Canseco
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Ratko Yurac
- Clinica Alemana de Santiago, University Del Desarrollo, Vitacura, Chile
| | | | - Eugen Cezar Popescu
- Department of Neurosurgery, “Prof. N. Oblu” Emergency Hospital, Iasi, Romania
| | - Richard Bransford
- Department of Orthopaedics and Sports Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
| | | | - Frank Kandziora
- Center for Spine Surgery and Neurotraumatology, BG Unfallklinik Frankfurt Am Main, Frankfurt, Germany
| | - Marko H. Neva
- Department of Orthopaedic and Trauma Surgery, Tampere University Hospital, Tampere, Finland
| | - Klaus John Schnake
- Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien Erlangen, Erlangen, Germany
- Department of Orthopedics and Traumatology, Paracelsus Private Medical University Nuremberg, Nuremberg, Germany
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7
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De Robertis M, Anselmi L, Baram A, Tropeano MP, Morenghi E, Ajello D, Cracchiolo G, Capo G, Tomei M, Ortolina A, Fornari M, Brembilla C. Percutaneous Treatment of Traumatic A3 Burst Fractures of the Thoracolumbar Junction Without Neurological Impairment: The Role of Timing and Characteristics of Fragment Blocks on Ligamentotaxis Efficiency. J Clin Med 2025; 14:2772. [PMID: 40283602 PMCID: PMC12027751 DOI: 10.3390/jcm14082772] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/09/2025] [Revised: 04/06/2025] [Accepted: 04/16/2025] [Indexed: 04/29/2025] Open
Abstract
Background: This study aims to evaluate how surgical timing and the radiological characteristics of fragment blocks can affect the effectiveness of ligamentotaxis, in restoring the spinal canal area, and local kyphosis in adults with traumatic thoracolumbar A3 burst fractures without neurological impairment treated with percutaneous short-segment fixation. Methods: A retrospective observational study was conducted between January 2016 and December 2022 on neurologically intact adult patients with a single A3 thoracolumbar fracture. Data collected included demographics, injury mechanism, fracture level, and clinical and surgical details. Radiological assessments included spinal canal area, local kyphotic angle, anterior and posterior vertebral heights, and fragment block measurements. Results: Out of 101 treated patients, 9 met the criteria with a mean age of 52.22 years. Most fractures were at L1 (88.89%). All patients had moderate-to-severe pain (NRS 6.22 ± 1.09) at baseline. Five patients (55.55%) underwent surgery within 72 h, with a mean surgical time of 109.22 min. SCA and LKA values improved significantly in all patients post-surgery. Early surgical intervention (<72 h) correlated with greater improvements in spinal canal area (p = 0.016) and local kyphotic angle (p = 0.004). A significant association was found between spinal canal area improvement and the percentage ratio of fragment height to "normal" vertebral height (rho = 0.682; p = 0.043). Conclusions: Early (<72 h) short-segment percutaneous fixation is recommended for adults with high functional demands and moderate-to-severe axial pain due to single traumatic A3N0M0 thoracolumbar fracture. This "upfront" approach is associated with enhanced indirect decompression and better local kyphotic angle restoration. Considering the fragment morphology could also be important in surgical planning.
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Affiliation(s)
- Mario De Robertis
- Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Italy;
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
| | - Leonardo Anselmi
- Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Italy;
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
| | - Ali Baram
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
| | - Maria Pia Tropeano
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
| | - Emanuela Morenghi
- Biostatistics Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy;
| | - Daniele Ajello
- Neuroradiology Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy;
| | - Giorgio Cracchiolo
- School of Medicine and Surgery, Pope John XXIII Hospital, University of Milano-Bicocca, 24127 Bergamo, Italy;
| | - Gabriele Capo
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
| | - Massimo Tomei
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
| | - Alessandro Ortolina
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
| | - Maurizio Fornari
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
| | - Carlo Brembilla
- Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy; (A.B.); (M.P.T.); (G.C.); (M.T.); (A.O.); (M.F.); (C.B.)
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Feyling AC, Undén J, Marklund N, Malak I, Åstrand R, Posti JP, Brommeland T. Management of traumatic spinal cord injury in the Nordic countries: a multidisciplinary survey. Scand J Trauma Resusc Emerg Med 2025; 33:51. [PMID: 40128803 PMCID: PMC11934776 DOI: 10.1186/s13049-025-01349-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/04/2024] [Accepted: 02/19/2025] [Indexed: 03/26/2025] Open
Abstract
BACKGROUND Management of traumatic spinal cord injury is complex and depends on a multidisciplinary approach involving pre-hospital services, spinal surgery, intensive care unit treatment and specialized rehabilitation. International clinical practice guidelines for the handling of these patients offer specific recommendations regarding transportation, radiological investigations, timing of surgery, intensive care management and rehabilitation. We performed a comprehensive multicenter survey to assess the agreement between the Nordic countries on the different aspects of traumatic spinal cord injury management. METHODS Sequential, cross-sectional, structured survey comprising the key clinical domains (pre-hospital services, spinal surgery, intensive care management and rehabilitation) in all tertiary spine trauma centers in Sweden, Denmark, Norway, Iceland and Finland. Data are presented descriptively. RESULTS A total of 109 respondents from 22 Nordic centers were invited to take the survey, with a response rate of 90% (98/109). Overall, clinical practices were comparable within the domains. Prehospital services had similar practices for airway management, clinical spine clearance and patient transport. Preoperative magnetic resonance imaging was available to 33/35 of the spine surgeons (94%) on a 24/7 basis. This examination was considered mandatory prior to surgery by 66% (23/35) of the surgeons. Surgery was defined as early if performed within 24 h of the injury by all surveyed surgeons. Augmented blood pressure regimens were widely applied in the intensive care units, with mean arterial pressure targets varying between > 80 and > 90 mmHg. Postoperative thromboprophylaxis was administered within 48 h by all centers and rehabilitation policies were similar overall. Notable variations in practice were the occasional steroid administration and the use of lumbar drains in 54% (14/26) of intensive care units. CONCLUSION Although there is some variability in the current management of traumatic spinal cord injury in the Nordic countries at the center- and country-level, practices in most key clinical domains are similar and follow established international guidelines.
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Affiliation(s)
- Anders C Feyling
- Department of Anaesthesia and Intensive Care, Division of Emergencies & Critical Care, Oslo University Hospital Ullevål, Oslo, Norway.
- Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
- Department of Research & Development, Division of Emergencies & Critical Care, Oslo University Hospital, Oslo, Norway.
| | - Johan Undén
- Department of Operation and Intensive Care, Hallands Hospital Halmstad, Halmstad, Sweden
- Anesthesia and Intensive Care, Clinical Sciences, Lund University, Lund, Sweden
| | - Niklas Marklund
- Department of Clinical Sciences Lund, Neurosurgery, Lund University and Skåne University Hospital, Lund, Sweden.
| | - Ilke Malak
- Department of Orthopedic Surgery, Hallands Hospital Halmstad, Halmstad, Sweden
| | - Ramona Åstrand
- Department of Neurosurgery, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
| | - Jussi P Posti
- Neurocenter, Department of Neurosurgery and Turku Brain Injury Center, Turku University Hospital and University of Turku, Turku, Finland
| | - Tor Brommeland
- Neurosurgical department, Oslo University Hospital Ullevål, Oslo, Norway
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Aly MM, El-Sharkawi M, Joaquim AF, Pizones J, Santander Espinoza XA, Popescu EC, Bin Shebree N A, Gerdhem P, Öner CF. Toward Identifying and Resolving the Challenges to the Prognostic Validation of the Classifications for Thoracolumbar Burst Fractures: A Narrative Review. Clin Spine Surg 2025:01933606-990000000-00466. [PMID: 40125834 DOI: 10.1097/bsd.0000000000001764] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/05/2024] [Accepted: 01/20/2025] [Indexed: 03/25/2025]
Abstract
OBJECTIVE To review the historical thoracolumbar burst fractures (TLBFs) classifications and discuss the probable gaps for their clinical validation. SUMMARY OF BACKGROUND DATA Despite multiple classification schemes, the treatment decisions for TLBFs in neurologically intact patients remain controversial. There are gaps between the current classifications and their predictive validation. METHODS A narrative literature review. RESULTS The potential barriers to establishing the predictive value of the current classifications of TLBFs could be connected to validation studies' flaws such as nonvalidated outcome measures and challenges of randomization. It could also be related to limited interobserver reliability in diagnosing A3/A4 fractures. Finally, it might be attributed to the inability to incorporate all prognostic variables, such as computed tomography (CT) parameters, patient-related factors, and traumatic disc injury, may result in failed validation. CONCLUSION AOSpine Patient and Clinical Reported Outcome Spine Trauma (PROST) and a recently proposed natural experiment observational study hold promise for mitigating methodological challenges. A structured approach for distinguishing A3/A4 fractures and standardized CT criteria for PLC injury is critical to improving reliability. Finally, a treatment algorithm incorporating all potential prognostic variables, independent of the morphologic classification, may improve the predictive value of the classification. Machine learning techniques could be helpful in this context.
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Affiliation(s)
- Mohamed M Aly
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia
| | | | - Andrei F Joaquim
- Division of Neurosurgery, Department of Neurosurgery, State University of Campinas, Campinas-Sao Paulo, Brazil
| | | | | | | | | | - Paul Gerdhem
- Department of Orthopedics and Hand Surgery, Uppsala University Hospital, Uppsala
- Department of Surgical Sciences, Uppsala University, Sweden
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Scherer J, Bigdon SF, Camino-Willhuber G, Spiegl U, Joaquim AF, Chhabra HS, Dvorak M, Schroeder G, El-Sharkawi M, Bransford R, Benneker LM, Schnake KJ, on behalf of the AO Spine-DGOU international validation Group. Validation of the AOSpine-DGOU Osteoporotic Fracture Classification - Effect of Surgical Experience, Surgical Specialty, Work-Setting and Trauma Center Level on Reliability and Reproducibility. Global Spine J 2025:21925682251331945. [PMID: 40125826 PMCID: PMC11948244 DOI: 10.1177/21925682251331945] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/17/2024] [Revised: 02/22/2025] [Accepted: 03/18/2025] [Indexed: 03/25/2025] Open
Abstract
Study DesignCross-sectional survey.ObjectivesA cornerstone of classification systems is good reliability amongst different groups of classification users. Thus, the aim of this international validation study was to assess the reliability of the new AO Spine DGOU Osteoporotic Fracture Classification (OF classification) stratified by surgical specialty, work-setting, work-experience, and trauma center level.Methods320 spine surgeons were asked to rate 27 cases according to the OF classification at 2 time points, 4 weeks apart (assessment 1 and 2) in this online-webinar based validation process. The kappa statistic (κ) was calculated to assess the inter-observer reliability and the intra-rater reproducibility.ResultsA total of 7798 (90.3%) ratings were recorded in assessment 1 and 6621 (76.6%) ratings in assessment 2. Global inter-rater reliability was moderate in both assessments (κ = 0.57; κ = 0.58). Participants with a work-experience of >20 years showed the highest inter-rater agreement in both assessments globally (κ = 0.65; κ = 0.67). Participants from a level-1 trauma center showed the highest agreement (κ = 0.58), whereas participants working at a tertiary trauma center showed higher grade of agreement in the second assessment (κ = 0.66). Participants working in academia showed the highest agreement in assessment 2 (κ = 0.6). Surgeons with academic background and surgeons employed by a hospital showed substantial intra-rater agreement in the second assessment.ConclusionsThe AO Spine-DGOU Osteoporotic Fracture Classification showed moderate to substantial inter-rater agreement as well as intra-rater reproducibility regardless of work-setting, surgical experience, level of trauma center and surgical specialty.
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Affiliation(s)
- Julian Scherer
- Orthopaedic Research Unit, University of Cape Town, Cape Town, South Africa
- Department of Traumatology, University Hospital of Zurich, Zürich, Switzerland
| | - Sebastian Frederick Bigdon
- Department for Orthopaedics and Traumatology, Inselspital, University Hospital Bern, Bern, Switzerland
- Department for Spine Surgery, Sonnenhof Spital, University of Bern, Bern, Switzerland
| | | | - Ulrich Spiegl
- Klinik für Unfallchirurgie und Orthopädie, Klinik München Harlaching, München, Germany
| | - Andrei Fernandes Joaquim
- Neurosurgery Division, Department of Neurology, State University of Campinas, Campinas-Sao Paulo, Brazil
| | | | - Marcel Dvorak
- Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada
| | - Gregory Schroeder
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Mohammad El-Sharkawi
- Department of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt
| | - Richard Bransford
- Department of Orthopaedics and Sports Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
| | | | - Klaus John Schnake
- Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien Erlangen, Erlangen, Germany
- Department of Orthopedics and Traumatology, Paracelsus Private Medical University Nuremberg, Nuremberg, Germany
| | - on behalf of the AO Spine-DGOU international validation Group
- Orthopaedic Research Unit, University of Cape Town, Cape Town, South Africa
- Department of Traumatology, University Hospital of Zurich, Zürich, Switzerland
- Department for Orthopaedics and Traumatology, Inselspital, University Hospital Bern, Bern, Switzerland
- Department for Spine Surgery, Sonnenhof Spital, University of Bern, Bern, Switzerland
- Policina Gipuzkoa, San Sebastian, Spain
- Klinik für Unfallchirurgie und Orthopädie, Klinik München Harlaching, München, Germany
- Neurosurgery Division, Department of Neurology, State University of Campinas, Campinas-Sao Paulo, Brazil
- Sri Balaji Action Medical Institute, New Delhi, India
- Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
- Department of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt
- Department of Orthopaedics and Sports Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
- Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien Erlangen, Erlangen, Germany
- Department of Orthopedics and Traumatology, Paracelsus Private Medical University Nuremberg, Nuremberg, Germany
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11
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Pieroh P, Heyde CE. [Indications for surgical treatment of traumatic fractures of the thoracic spine and lumbar spine]. UNFALLCHIRURGIE (HEIDELBERG, GERMANY) 2025; 128:156-166. [PMID: 39869224 DOI: 10.1007/s00113-024-01518-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Accepted: 11/25/2024] [Indexed: 01/28/2025]
Abstract
Fractures of the thoracic (Th) and lumbar (L) vertebrae are among the most frequent fracture entities in Germany and particularly affect the thoracolumbar junction (TLJ; Th11-L2). Based on expert recommendations and consensus meetings, the thoracolumbar AOSpine injury score was established for patients with healthy bone and the osteoporotic fracture (OF) score for geriatric patients with the respective classifications for treatment decisions. In both cohorts, the treatment decision is based on the fracture morphology, neurological status and patient-specific contextual factors. In terms of fracture morphology, surgical treatment is generally indicated for distraction and rotation/translation injuries. The treatment decision for compression fractures is more complex as additional factors must be taken into consideration. The decision in patients with healthy bone is primarily influenced by imaging morphological criteria (deformity and destruction) whereas in osteoporotic patients the decision is influenced by individual criteria, such as the general condition, the possibility of low pain mobilization and concomitant diseases. Overall, the treatment decision for fractures of the TLJ is not dogmatic as individual factors must be considered and high-quality studies are lacking.
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Affiliation(s)
- Philipp Pieroh
- Klinik für Orthopädie, Unfallchirurgie und Plastische Chirurgie, Universitätsklinikum Leipzig AöR, Liebigstraße 20, 04103, Leipzig, Deutschland.
| | - Christoph-E Heyde
- Klinik für Orthopädie, Unfallchirurgie und Plastische Chirurgie, Universitätsklinikum Leipzig AöR, Liebigstraße 20, 04103, Leipzig, Deutschland
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12
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Nandolia K, Saran S, Varshney G, Shirodkar K, Iyengar KP, Botchu R. Spine Trauma Classifications: Historical, Current, and Emerging Perspectives for Radiologists. Indian J Radiol Imaging 2025. [DOI: 10.1055/s-0045-1805025] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/18/2025] Open
Abstract
AbstractThe spine serves as a protective, load-bearing, and stabilizing axis for the body. Trauma can cause significant damage to spinal structures, potentially resulting in severe neurological dysfunction and disabilities such as paraplegia or quadriplegia. Early and accurate diagnosis of these injuries is important, with computed tomography and magnetic resonance imaging being important for recognizing these injuries and guiding timely treatment to minimize disability. Radiologists play a critical role in assessing spine trauma to determine stability, which informs the need for nonoperative or operative management. Trauma classification systems are vital for uniform communication between radiologists and surgeons, aiding in decision-making. Various classifications exist for cervical, thoracolumbar, and sacral trauma, each with advantages and limitations. Understanding these classification systems is essential for guiding diagnosis, treatment, and prognostication. Over the years, these systems have evolved, reflecting advancements in medical knowledge, imaging technology, and clinical practices. Contemporary classification systems have addressed the limitations of previous systems. Vaccaro et al proposed the “Thoracolumbar Injury Classification and Severity Score (TLICS)” in 2005 and the “Subaxial Cervical Spine Injury Classification System” in 2007. These classifications focus on injury morphology, the integrity of the posterior ligamentous complex or discoligamentous complex, and the patient's neurologic status. The Arbeitsgemeinschaft für Osteosynthesefragen (AO) founded the “Spine Classification Group” to review the “AO-Magerl classification” and create an extensive system for the whole spine. This system focuses on fracture morphology, neurological status, clinical modifiers, and facet joint injury. The TLICS system is straightforward and easy to use in clinical practice, while the AOSpine system is more comprehensive and reliable. As classification systems evolve, collaboration among radiologists, spine surgeons, and researchers will be essential. By embracing advancements in imaging technology and incorporating new clinical data, the field of spine trauma classification can achieve greater accuracy and consistency, ultimately enhancing patient care and outcomes.
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Affiliation(s)
- Khanak Nandolia
- Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
| | - Sonal Saran
- Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
| | - Garima Varshney
- Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
| | - Kapil Shirodkar
- Department of Musculoskeletal Radiology, Royal Orthopaedic Hospital, Birmingham, United Kingdom
| | - Karthikeyan P. Iyengar
- Department of Orthopaedics, Southport and Ormskirk Hospitals, National Health Service Trust, Southport, United Kingdom
| | - Rajesh Botchu
- Department of Musculoskeletal Radiology, Royal Orthopaedic Hospital, Birmingham, United Kingdom
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13
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Mo AZ, Lockey S, Mo F. The Posterior Ligamentous Complex: Anatomic and Biomechanical Considerations in Injury Classification and Management. J Am Acad Orthop Surg 2025:00124635-990000000-01230. [PMID: 39874161 DOI: 10.5435/jaaos-d-22-00908] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/02/2022] [Accepted: 12/16/2024] [Indexed: 01/30/2025] Open
Abstract
The posterior ligamentous complex (PLC) provides critical structural support in the thoracolumbar spine. Its role in resisting progressive flexion is particularly important at the thoracolumbar junction due to the transition from the rigid thoracic spine to the more mobile lumbar region. Each component of the PLC contains anatomic features that contribute to both the structure and function of the PLC as a whole. Understanding the nuances of each structure is important in determining injury severity and may serve as a foundation for future directions of research. Violation of the PLC results in an unstable spine, thus requiring surgical management. It is associated with greater injury severity and neurologic deficit in patients who sustain thoracolumbar fractures, which adds complexity to the postoperative course and patient outcomes. Although plain radiographs and CT scans provide reliable indirect measures of PLC disruption, these modalities may be subject to diminished sensitivity based on patient positioning and do not directly measure soft-tissue injury. Modern classification systems include the integrity of the PLC in surgical decision making, and care must be taken to scrutinize the possibility of ligamentous disruption before proceeding with nonsurgical management to avoid adverse patient outcomes.
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Affiliation(s)
- Andrew Z Mo
- From the Department of Orthopaedics (A. Mo and F. Mo), Medstar Georgetown University Hospital, Washington, DC, and the Department of Orthopaedic Surgery (S. Lockey), University of Virginia, Charlottesville, VA
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14
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Withrow J, Trimble D, Narro A, Monterey M, Sheinberg D, Dono A, Haley L, Cruz MM, Zaragoza J, Li W, Quinn J. Validation and Comparison of Common Thoracolumbar Injury Classification Treatment Algorithms and a Novel Modification. Neurosurgery 2025; 96:172-182. [PMID: 38920381 DOI: 10.1227/neu.0000000000003055] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/02/2024] [Accepted: 04/24/2024] [Indexed: 06/27/2024] Open
Abstract
BACKGROUND AND OBJECTIVES The most common thoracolumbar trauma classification systems are the Thoracolumbar Injury Classification and Severity Score (TLICS) and the Thoracolumbar AO Spine Injury Score (TL AOSIS). Predictive accuracy of treatment recommendations is a historical limitation. Our objective was to validate and compare TLICS, TL AOSIS, and a modified TLICS (mTLICS) that awards 2 points for the presence of fractured vertebral body height loss >50% and/or spinal canal stenosis >50% at the fracture site. METHODS The medical records of adult patients with acute, traumatic thoracolumbar injuries at an urban, Level 1 trauma center were retrospectively reviewed. TLICS, mTLICS, and TL AOSIS scores were calculated for 476 patients using computed tomography, MRI, and the documented neurological examination. Treatment recommendations were compared with treatment received. Standard validity measures were calculated. RESULTS Treatment recommendations matched actual treatments in 95.6% (455/476) of patients for mTLICS, 91.3% (435/476) for TLICS, and 92.6% (441/476) for TL AOSIS. The differences between the accuracy of mTLICS and TLICS (95.6% vs 91.3%, P < .001) and between mTLICS and TL AOSIS (95.6% vs 91.3%, P = .003) were significant. The sensitivity of mTLICS was higher than that of TLICS (96.3% vs 81.3%, P < .001), and the sensitivity of TL AOSIS was higher than that of TLICS (92.5% vs 81.3%, P < .001). The specificity of mTLICS was equal to that of TLICS (95.3%) and higher than that of TL AOSIS (95.3% vs 92.7%, P = .02). The modifier led to substantial outperformance of mTLICS over TLICS due to 38 patients (20 of whom received surgery) moving from a TLICS score of <4 to a mTLICS score equal to 4. CONCLUSION All systems performed well. The mTLICS had improved sensitivity and accuracy compared with TLICS and higher accuracy and specificity than TL AOSIS. The sensitivity of TL AOSIS was higher than that of TLICS. Prospective, multi-institutional reliability and validity studies of this mTLICS are needed for adoption.
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Affiliation(s)
- Joseph Withrow
- Department of Neurosurgery, McGovern Medical School, UTHealth Houston, Houston , Texas , USA
| | - Duncan Trimble
- Department of Neurosurgery, McGovern Medical School, UTHealth Houston, Houston , Texas , USA
| | - Analisa Narro
- McGovern Medical School, UTHealth Houston, Houston , Texas , USA
| | - Michael Monterey
- Department of Neurosurgery, McGovern Medical School, UTHealth Houston, Houston , Texas , USA
- Current Affiliation: Department of Neurosurgery, Miller School of Medicine, University of Miami, Miami , Florida , USA
| | - Dallas Sheinberg
- Department of Neurosurgery, McGovern Medical School, UTHealth Houston, Houston , Texas , USA
| | - Antonio Dono
- Department of Neurosurgery, McGovern Medical School, UTHealth Houston, Houston , Texas , USA
| | - Lauren Haley
- McGovern Medical School, UTHealth Houston, Houston , Texas , USA
| | | | - Jennifer Zaragoza
- Department of Neurosurgery, McGovern Medical School, UTHealth Houston, Houston , Texas , USA
| | - Wen Li
- Division of Clinical and Translational Sciences, Department of Internal Medicine, UTHealth Houston, Houston , Texas , USA
| | - John Quinn
- Department of Neurosurgery, McGovern Medical School, UTHealth Houston, Houston , Texas , USA
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15
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Kwon WK, Ham CH, Byun J, Jeong JH, Ko MJ, Lee S, Lee BJ, Kim JH. Surgical and Neurointensive Management for Acute Spinal Cord Injury: A Narrative Review. Korean J Neurotrauma 2024; 20:225-233. [PMID: 39803341 PMCID: PMC11711025 DOI: 10.13004/kjnt.2024.20.e44] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/10/2024] [Revised: 12/11/2024] [Accepted: 12/15/2024] [Indexed: 01/16/2025] Open
Abstract
Spinal cord injury (SCI) following high-energy trauma often leads to lasting neurologic deficits and severe socioeconomic impact. Effective neurointensive care, particularly in the early stages post-injury, is essential for optimizing outcomes. This review discusses the role of neurointensive care in managing SCI, emphasizing early assessment, stabilization, and intervention strategies based on recent evidence-based practices. SCI results from primary mechanical damage to the spinal cord, triggering secondary injuries involving vascular and cellular dysfunction. Early neurointensive care focuses on stabilizing airway, breathing, and circulation while preventing further spinal damage. Imaging and neurologic assessments, including the ASIA scale, guide the management plan. Early decompressive surgery within 24 hours is widely supported for patients with spinal instability or cord compression. Pharmacologic strategies aim to reduce secondary injury, though standardization remains limited. Prophylaxis for deep vein thrombosis and pulmonary embolism, intensive pulmonary support, and monitoring for pressure sores are critical in early-phase SCI. Early neurointensive care and surgical interventions play a pivotal role in mitigating SCI progression. Optimal care requires a multifaceted approach addressing both neurologic and systemic complications, significantly influencing recovery and long-term quality of life. Further research is needed to standardize pharmacologic treatments and optimize surgical timing.
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Affiliation(s)
- Woo-Keun Kwon
- Department of Neurosurgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
| | - Chang-Hwa Ham
- Department of Neurosurgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
| | - Joonho Byun
- Department of Neurosurgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
| | - Je Hoon Jeong
- Department of Neurosurgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
| | - Myeong Jin Ko
- Department of Neurosurgery, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea
| | - Subum Lee
- Department of Neurosurgery, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea
| | - Byung-Jou Lee
- Department of Neurosurgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea
| | - Jong Hyun Kim
- Department of Neurosurgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
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16
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Sun X, Huang J, Wang W, Gan L, Cao L, Liu Y, Sun S, Wang J, Lu S. Analysis of factors influencing the surgical treatment outcomes of spinal injuries in polytrauma patients. Ann Med Surg (Lond) 2024; 86:6960-6967. [PMID: 39649898 PMCID: PMC11623812 DOI: 10.1097/ms9.0000000000002704] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/23/2024] [Accepted: 10/21/2024] [Indexed: 12/11/2024] Open
Abstract
Background This study aims to analyze the diagnosis and treatment conditions of polytrauma patients with spinal injuries, to clarify the site of the first surgical intervention, the timing of the surgery, and factors influencing prognosis. Methods This study collected and analyzed data on polytrauma patients with spinal injuries who were treated from January 2017 to January 2023. Data collected primarily included basic patient information, treatment strategy-related information, clinical scoring systems, imaging parameters, and prognosis. The impacts of relevant variables on postoperative survival outcomes were analyzed. Results This study included 60 patients. There was no significant change in the number of patients rated ASIA grade E after 90 days of admission, while there was a significant increase in those rated grade D (P<0.001). Among the groups, patients operated on within less than 12 h had the highest number of ASIA grade A, while those operated on after more than 48 h had the highest number of ASIA grade E (P=0.003). The survival rate of patients who underwent their first spinal surgery between 12 and 48 h was significantly better than those operated earlier than 12 h or later than 48 h (P=0.047). Patients who experienced hemorrhagic shock postsurgery had the lowest survival rate (P<0.001). Only age (P=0.004) and the number of surgeries outside the spine (P=0.033), as covariates, were significantly correlated with patient mortality (R2=0.519). Conclusions Performing spinal surgery too early or too late can adversely affect patient outcomes; the appropriate timing of surgery should be chosen based on the specific characteristics of the patient. In polytrauma patients under emergency conditions, the use of combined surgical treatments should be minimized to prevent the occurrence of a 'second hit'. Patients who experience hemorrhagic shock have the worst postsurgical survival; targeted treatment should be administered upon hospital admission.
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Affiliation(s)
- Xiangyao Sun
- Department of Orthopedics, Xuanwu Hospital Capital Medical University, Beijing, People’s Republic of China
- National Clinical Research Center for Geriatric Diseases, Beijing, People’s Republic of China
- Beijing Glitzern Technology Co. Ltd, Beijing, People’s Republic of China
| | - Jiang Huang
- Department of Orthopedics, Xuanwu Hospital Capital Medical University, Beijing, People’s Republic of China
- National Clinical Research Center for Geriatric Diseases, Beijing, People’s Republic of China
| | - Weiliang Wang
- Department of Traumatology, Beijing Daxing District People’s Hospital, Beijing, People’s Republic of China
| | - Limeng Gan
- Department of Orthopedics, Beijing Daxing District People’s Hospital, Beijing, People’s Republic of China
| | - Li Cao
- Department of Orthopedics, Xuanwu Hospital Capital Medical University, Beijing, People’s Republic of China
- National Clinical Research Center for Geriatric Diseases, Beijing, People’s Republic of China
| | - Yuqi Liu
- Department of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China
| | - Siyuan Sun
- Department of Interdisciplinary, Life Science, Purdue University, West Lafayette, Indiana, USA
| | - Juyong Wang
- Department of Orthopedics, Xuanwu Hospital Capital Medical University, Beijing, People’s Republic of China
- National Clinical Research Center for Geriatric Diseases, Beijing, People’s Republic of China
| | - Shibao Lu
- Department of Orthopedics, Xuanwu Hospital Capital Medical University, Beijing, People’s Republic of China
- National Clinical Research Center for Geriatric Diseases, Beijing, People’s Republic of China
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17
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Vaccaro AR. Editorial review of the validation of thoracolumbar injury classification and severity score in the management of acute and subacute osteoporotic vertebral compression fractures. INTERVENTIONAL PAIN MEDICINE 2024; 3:100441. [PMID: 39483972 PMCID: PMC11526067 DOI: 10.1016/j.inpm.2024.100441] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Download PDF] [Subscribe] [Scholar Register] [Received: 09/27/2024] [Accepted: 09/30/2024] [Indexed: 11/03/2024]
Affiliation(s)
- Alexander R. Vaccaro
- Department of Orthopaedic Surgery, Rothman Orthopaedic Institute at Thomas Jefferson University Hospital, Philadelphia, PA, USA
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18
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Taghlabi KM, Guerrero JR, Bhenderu LS, Xu J, Nanda R, Somawardana IA, Baradeiya AMA, Tahanis A, Cruz-Garza JG, Freyvert Y, Trask TW, Huang M, Barber SM, Holman PJ, Faraji AH. Influence of Hospital Transfer Status on Surgical Outcomes for Traumatic Thoracolumbar Spine Fractures: Insights from a Multicenter Investigation. World Neurosurg 2024; 190:e637-e647. [PMID: 39098504 DOI: 10.1016/j.wneu.2024.07.197] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/05/2024] [Revised: 07/26/2024] [Accepted: 07/27/2024] [Indexed: 08/06/2024]
Abstract
OBJECTIVE Surgical intervention for unstable thoracolumbar spine fractures is common, but delayed management and complications can impact outcomes. This study compares perioperative outcomes between patients directly admitted and those transferred from another facility for thoracolumbar spine surgery, aiming to identify predictors of complications and mortality. METHODS A multicenter retrospective cohort study used the American College of Surgeons National Surgical Quality Improvement Program database from 2011 to 2021 identified 61,626 patients undergoing fusion surgeries for thoracolumbar spine fractures, excluding spinal cord injury or pathological fractures. Patients were categorized as Direct (admitted from the emergency department) and Transfer (transferred from another facility). Perioperative outcomes, including operative time, length of stay (LOS), 30-day mortality, and complications, were compared. RESULTS Our patient population (54.3% female, mean age 62.4 ± 12.9 years) comprised 12.2% Transfer and 87.8% Direct patients. Following propensity score matching, Transfer patients had a longer hospital LOS (5.1 ± 5.7 days vs. 4.5 ± 4.6 days, P < 0.001). Transfer exhibited higher rates of superficial incisional surgical site infection (1.7% vs. 1.1%, P = 0.003), sepsis (1.7% vs. 1.3%, P = 0.038), pneumonia (1.7% vs. 1.2%, P = 0.019), postoperative reintubation (0.9% vs. 0.6%, P = 0.036), and failure to wean off ventilator >48 hours postsurgery (0.7% vs. 0.3%, P = 0.005) compared to Direct admissions. Direct group had a higher rate of perioperative transfusion (16.5% vs. 13.4%, P < 0.001). Transfer patients also had a higher 30-day mortality rate compared to Direct admissions (1.1% vs. 0.6%, P = 0.002). CONCLUSIONS Interhospital transfers significantly affect hospital LOS, postoperative morbidity, and mortality in thoracolumbar spine surgery. Enhancing postoperative monitoring for transfer patients is crucial.
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Affiliation(s)
- Khaled M Taghlabi
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA; Clinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, Texas, USA.
| | - Jaime R Guerrero
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA; Clinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, Texas, USA
| | - Lokeshwar S Bhenderu
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA; Clinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, Texas, USA
| | - Jiaqiong Xu
- Center for Health Data Science and Analytics, Department of Medicine, Houston Methodist Research Institute, Houston, Texas, USA
| | - Rijul Nanda
- Clinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, Texas, USA; School of Engineering Medicine, Texas A&M University, Houston, Texas, USA
| | - Isuru A Somawardana
- Clinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, Texas, USA; School of Engineering Medicine, Texas A&M University, Houston, Texas, USA
| | | | - Aboud Tahanis
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA
| | - Jesus G Cruz-Garza
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA; Clinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, Texas, USA
| | - Yevgeniy Freyvert
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA
| | - Todd W Trask
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA
| | - Meng Huang
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA
| | - Sean M Barber
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA
| | - Paul J Holman
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA
| | - Amir H Faraji
- Department of Neurological Surgery, Houston Methodist Hospital, Houston, Texas, USA; Clinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, Texas, USA
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19
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Quinones C, Wilson JP, Kumbhare D, Guthikonda B, Hoang S. Clinical Assessment and Management of Acute Spinal Cord Injury. J Clin Med 2024; 13:5719. [PMID: 39407779 PMCID: PMC11477398 DOI: 10.3390/jcm13195719] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/26/2024] [Revised: 09/09/2024] [Accepted: 09/22/2024] [Indexed: 10/20/2024] Open
Abstract
The information contained in this article is suitable for clinicians practicing in the United States desiring a general overview of the assessment and management of spinal cord injury (SCI), focusing on initial care, assessment, acute management, complications, prognostication, and future research directions. SCI presents significant challenges, affecting patients physically, emotionally, and financially, with variable recovery outcomes ranging from full functionality to lifelong dependence on caregivers. Initial care aims to minimize secondary injury through thorough neurological evaluations and imaging studies to assess the severity of the injury. Acute management prioritizes stabilizing respiratory and cardiovascular functions and maintaining proper spinal cord perfusion. Patients with unstable or progressive neurological decline benefit from timely surgical intervention to optimize neurological recovery. Subacute management focuses on addressing common complications affecting the respiratory, gastrointestinal, and genitourinary systems, emphasizing a holistic, multidisciplinary approach. Prognostication is currently based on neurological assessments and imaging findings, but emerging biomarkers offer the potential to refine outcome predictions further. Additionally, novel therapeutic interventions, such as hypothermia therapy and neuroprotective medications are being explored to mitigate secondary damage and enhance recovery. This paper serves as a high-yield refresher for clinicians for the assessment and management of acute spinal cord injury during index admission.
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Affiliation(s)
| | | | | | | | - Stanley Hoang
- Department of Neurosurgery, Louisiana State University Health Shreveport, Shreveport, LA 71103, USA; (C.Q.); (J.P.W.J.); (D.K.); (B.G.)
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Gill JS, Stippler M, Ruan Q, Hussain N, White AP, Oruhurhu V, Malik O, Simopoulos T, Urits I, D'Souza RS, Narang S, Hirsch JA. Validation of thoracolumbar injury classification and Severity Score in the management of acute and subacute Osteoporotic vertebral compression fractures - A pilot study and a suggested modification. INTERVENTIONAL PAIN MEDICINE 2024; 3:100438. [PMID: 39309034 PMCID: PMC11415955 DOI: 10.1016/j.inpm.2024.100438] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 08/12/2024] [Revised: 08/29/2024] [Accepted: 08/29/2024] [Indexed: 09/25/2024]
Abstract
Objective To retrospectively assess the Thoracolumbar Injury Classification and Severity Score (TLICS) in patients with osteoporotic vertebral compression fractures (OVCF) and compare the treatment given with that predicted by the TLICS score. Methods All medical records of patients presenting from January 2014 to November 2017 for acute atraumatic or low impact OVCF were screened, and eligible patients were retrospectively reviewed. The TLICS score was determined based upon magnetic resonance imaging (MRI) findings and clinical records. Clinical records (including pain score data), imaging data, operative procedures, and stability of neurological examination were tracked over three months for each patient. Results Of the 56 patients included, 36 patients had a TLICS score of 1, 18 had a TLICS score of 2, and two had a TLICS score of 4. Only one patient with a TLICS score of 4 underwent surgical stabilization, while the rest of the cohort was managed non-operatively, with or without kyphoplasty. TLICS score 1 corresponded to simple compression and TLICS score 2 corresponded to burst morphology with retropulsion and without neurological deficits. Of the patients with a TLICS score of 1 and 2 who underwent kyphoplasty, there was a statistically significant improvement in pain scores in both groups; however no significant difference was observed, between each TLICS score (i.e., 1 or 2). None of the patients developed instability or neurological decline. Conclusion TLICS score correctly predicted operative versus non-operative management in all patients with OVCF. TLICS may be used in making management decisions, and in the triage of these patients for operative versus non-operative evaluations. Our study suggests that patients with TLICS score of 4 or higher require surgical evaluation, while those with TLICS of 1 or 2 are likely to have satisfactory non-surgical management with augmentation or conservative care. In general, patients with OVCF typically present with low TLICS score. Kyphoplasty appears to be similarly beneficial in patients with a TLICS score of 1 or a TLICS score of 2. A modification of the TLICS score by adding TLICS Zero to include uncompressed OVCF with edema is suggested. The limitations of this study include a small size; a larger study is needed to confirm these findings.
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Affiliation(s)
- Jatinder S. Gill
- Department of Anesthesiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
| | - Martina Stippler
- Department of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
| | - Qing Ruan
- Department of Anesthesiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
| | - Nasir Hussain
- Department of Anesthesiology, The Ohio State University, Wexner Medical Center, Columbus, OH, USA
| | - Andrew P. White
- Department of Orthopedics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
| | - Vwaire Oruhurhu
- Department of Anesthesia, Division of Pain Medicine, University of Pittsburgh Medical Center, Susquehanna, PA, USA
| | | | - Thomas Simopoulos
- Department of Anesthesiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
| | - Ivan Urits
- Southcoast Health, Pain Management, Wareham, MA, USA
| | - Ryan S. D'Souza
- Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA
| | - Sanjeet Narang
- Department of Anesthesiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
| | - Joshua A. Hirsch
- Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
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Wendt K, Nau C, Jug M, Pape HC, Kdolsky R, Thomas S, Bloemers F, Komadina R. ESTES recommendation on thoracolumbar spine fractures : January 2023. Eur J Trauma Emerg Surg 2024; 50:1261-1275. [PMID: 37052627 PMCID: PMC11458676 DOI: 10.1007/s00068-023-02247-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/17/2022] [Accepted: 02/08/2023] [Indexed: 04/14/2023]
Affiliation(s)
- Klaus Wendt
- University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
| | - Christoph Nau
- University Hospital Frankfurt, Goethe University, Frankfurt, Germany
| | - Marko Jug
- University Medical Centre Ljubljana, University of Ljubljana, Ljubljana, Slovenia
| | | | - Richard Kdolsky
- University Clinic for Trauma Surgery, Medical University of Vienna, Vienna, Austria
| | | | - Frank Bloemers
- Amsterdam University Medical Centre, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
| | - Radko Komadina
- Medical Faculty, University of Ljubljana, Ljubljana, Slovenia
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Khil EK, Choi I, Lee KY, Kim YW. Can conservative treatment be effective for thoracolumbar injuries patients with TLICS scores of 4 or 5? An analysis of initial radiological findings and clinical risk factors for treatment failure. BMC Musculoskelet Disord 2024; 25:431. [PMID: 38831305 PMCID: PMC11145871 DOI: 10.1186/s12891-024-07543-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/10/2024] [Accepted: 05/27/2024] [Indexed: 06/05/2024] Open
Abstract
BACKGROUND This study aimed to assess the outcomes of conservative management in patients with thoracolumbar fractures classified with a Thoracolumbar Injury Classification and Severity (TLICS) score of 4 or 5, and to analyze initial imaging findings and clinical risk factors associated with treatment failure. METHODS In this retrospective analysis, patients with thoracolumbar fractures and a TLICS score of 4 or 5, determined through MRI from January 2017 to December 2020, were included. Patients undergoing conservative treatment were categorized into two groups: Group 1 (treatment success) and Group 2 (treatment failure), based on initial and 6-month follow-up outcomes. Clinical data were compared between the two groups. Initial radiological assessments included three kyphosis measurements (Cobb angle, Gardner angle, and sagittal index [SI]), anterior and posterior wall height, and central canal compromise (CC). Additionally, risk factors contributing to treatment failure were analyzed. RESULTS The conservative treatment group comprised 84 patients (mean age, 60.25 ± 15.53; range 22-85; 42 men), with 57 in Group 1 and 27 in Group 2. Group 2 exhibited a higher proportion of women, older age, and lower bone mass density (p = 0.001-0.005). Initial imaging findings in Group 2 revealed significantly greater values for Cobb angle, SI, and CC (p = 0.001-0.045 or < 0.001; with cutoff values of 18.2, 12.8, and 7.8%, respectively), and lower anterior wall height (p = 0.001), demonstrating good to excellent interobserver agreement (0.72-0.99, p < 0.001). Furthermore, osteoporosis was identified as a significant risk factor (odds ratio = 5.64, p = 0.008). CONCLUSION Among patients with TLICS scores of 4 or 5, those experiencing conservative treatment failure exhibited unfavorable initial radiological findings, a higher proportion of women, advanced age, and osteoporosis. Additionally, osteoporosis emerged as a significant risk factor for treatment failure.
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Affiliation(s)
- Eun Kyung Khil
- Department of Radiology, Hallym University Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, 18450, Gyeonggi-do, Korea
- Department of Radiology, Fastbone Orthopedic Hospital, 127-27, Dongtansunhwan-daero, Hwaseong-si, Gyeonggi-do, Korea
| | - Il Choi
- Department of Neurological Surgery, Hallym University Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, 18450, Gyeonggi-do, Korea.
| | - Kyoung Yeon Lee
- Department of Radiology, Hallym University Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, 18450, Gyeonggi-do, Korea
| | - Young Woo Kim
- Department of Orthopedic Surgery, Hallym University Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Gyeonggi-do, 18450, Korea
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Bonsignore-Opp L, O'Donnell J, Agha O, Bach K, Metz L, Swarup I. Evaluation and Management of Thoracolumbar Spine Trauma in Pediatric Patients: A Critical Analysis Review. JBJS Rev 2024; 12:01874474-202406000-00002. [PMID: 38885326 DOI: 10.2106/jbjs.rvw.24.00045] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 06/20/2024]
Abstract
» Pediatric thoracolumbar trauma, though rare, is an important cause of morbidity and mortality and necessitates early, accurate diagnosis and management.» Obtaining a detailed history and physical examination in the pediatric population can be difficult. Therefore, the threshold for advanced imaging, such as magnetic resonance imaging, is low and should be performed in patients with head injuries, altered mental status, inability to cooperate with examination, and fractures involving more than 1 column of the spine.» The classification of pediatric thoracolumbar trauma is based primarily on adult studies and there is little high-level evidence examining validity and accuracy in pediatric populations.» Injury pattern and neurologic status of the patient are the most important factors when determining whether to proceed with operative management.
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Affiliation(s)
- Lisa Bonsignore-Opp
- Department of Orthopedic Surgery, University of California San Francisco, San Francisco, California
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24
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Lotan R, Hershkovich O. A Novel Bipedicular Dissociation Fracture Pattern of Vertebral Osteoporotic Fractures of the Elderly. J Am Acad Orthop Surg Glob Res Rev 2024; 8:01979360-202406000-00003. [PMID: 38814254 PMCID: PMC11142811 DOI: 10.5435/jaaosglobal-d-23-00241] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/28/2023] [Revised: 02/13/2024] [Accepted: 04/02/2024] [Indexed: 05/31/2024]
Abstract
INTRODUCTION CVFs are common, with several classification systems available. We have encountered osteoporotic vertebral fractures (OVFs) with PDF, a never-described fracture pattern.This study evaluates this unique fracture's characteristics. METHODS Retrospective study of surgically treated OVFs during 2016 to 2020. RESULTS Of 105 patients, 85 had classifiable OVFs and 20 had uni-PDF (n = 10, 9.5%) or bi-PDF (n = 10, 9.5%). Both cohorts mainly had single vertebral fractures and upper end plate involvement with cleft sign found in 30% of PDFs versus 15.3% of OVFs (P < 0.001), higher incidence of burst fractures (40% vs. 25.9%; P < 0.001). Posterior vertebral body collapse was higher for PDFs (13.2 ± 9.3% vs. 18.3 ± 8.5%; P = 0.02). Most OVFs underwent balloon kyphoplasty (BKP) (94%). Most bi-PDFs were regarded unstable; six patients underwent PSF (2 short PSF, 1 PSF + BKP, and 3 BKP with intravertebral pedicular lag screws at the fractured vertebra). Half of the bi-PDFs underwent BKP-developed nonunion. CONCLUSION Our study is novel in describing an unrecognized OVF pattern disregarded in current classification systems. We found notable differences in fracture characteristics, prefracture functional status, and surgical results between OVF and PDF cohorts. We suggest adding this fracture pattern as a unique OF-4 subtype or a specific entity between OF-4 and 5, with uni-PDF as type A and bi-PDF as type B.
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Affiliation(s)
- Raphael Lotan
- From the Department of Orthopedic Surgery, Wolfson Medical Center, Holon, Israel
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Li T, Yan J, Liu X, Hu J, Wang F. Efficacy and Safety of Conservative Treatment Compared With Surgical Treatment for Thoracolumbar Fracture With Score 4 Thoracolumbar Injury Classification and Severity (TLICS): A Systematic Review and Meta-analysis. Clin Spine Surg 2024; 37:230-241. [PMID: 37448163 PMCID: PMC11142650 DOI: 10.1097/bsd.0000000000001503] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/22/2022] [Accepted: 06/21/2023] [Indexed: 07/15/2023]
Abstract
STUDY DESIGN This was a systematic review and meta-analysis. OBJECTIVE The clinical outcomes, radiologic outcome, and complications were compared between surgical treatment and conservative treatment of thoracolumbar fractures with a Thoracolumbar Injury Classification and Severity (TLICS) score of 4. SUMMARY OF BACKGROUND DATA The thoracolumbar fracture is the main reason leading to the spinal cord injury. Some studies suggested that the treatment of TLICS=4 is a "gray zone." Hence, the efficacy and safety of surgical treatment and conservative treatment of thoracolumbar fractures with scores 4 TLICS was still debated. MATERIALS AND METHODS A comprehensive search of PubMed, Embase, and the Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), Chongqing VIP Database (VIP), and Wan Fang Database was performed up to October 2021. Relevant studies were identified using specific eligibility criteria and data was extracted and analyzed based on primary and secondary outcomes. RESULTS A total of 10 studies involving 555 patients were included (3 randomized controlled trials and 7 retrospective studies). There was no significant difference of hospital time (standardized mean difference=0.24, 95% CI: -1.50 to 1.97, P =0.79) and Oswestry Disability Index (mean difference=2.97, 95% CI: -1.07 to 7.01, P =0.15) between surgery and nonsurgery. The length of returning to work was shorter in surgical treatment (standardized mean difference=1.27, 95% CI: 0.07-2.46, P =0.04). Visual Analog Scale in surgical treatment was lower at 1, 3, and 6 months (respectively, P <0.00001, P =0.003, and P =0.02). However, there existed no significant difference between surgical treatment and nonsurgical treatment at 12 and >24 months (respectively, P =0.18 and 0.17). Cobb angle was lower in surgical treatment at postoperative at 6, 12, and >24 months (respectively, P =0.005, P <0.00001, P =0.002, and P =0.0002). Finally, the surgical treatment had a lower incidence of complications (odds ratio=3.89, 95% CI: 1.90-7.94, P =0.0002). CONCLUSIONS Current evidence recommended that surgical treatment is superior to conservative treatment of TLICS score of 4 at the early follow-up. Surgical treatment had lower Cobb angle, Visual Analog Scale scores, and complications compared with a nonsurgical TLICS score of 4. However, these findings needed to be verified further by multicenter, double-blind, and large-sample randomized controlled trials.
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Affiliation(s)
- Ting Li
- Department of Orthopedics, Sichuan People’s Hospital
- Department of Postgraduate, Chengdu Medical College, Chengdu
| | - Jingxin Yan
- Department of Postgraduate, Qinghai University
- Departments of Interventional Therapy
- Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Qinghai University, Xining, China
| | - Xilin Liu
- Department of Orthopedics, Sichuan People’s Hospital
| | - Jiang Hu
- Department of Orthopedics, Sichuan People’s Hospital
| | - Fei Wang
- Department of Orthopedics, Sichuan People’s Hospital
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Preeth S, B V, C R. Contiguous Burst Fractures of the Lumbar Spine. Cureus 2024; 16:e63313. [PMID: 39070378 PMCID: PMC11283331 DOI: 10.7759/cureus.63313] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 06/27/2024] [Indexed: 07/30/2024] Open
Abstract
Burst fractures of vertebrae are usually caused by high-energy axial compression force, mostly caused by fall from height or road traffic accidents. They frequently occur at the thoracolumbar junction mostly requiring surgery. Contiguous burst fractures involving multiple lumbar vertebrae are uncommon. This case is a male in his early 40s presented with low back pain and weakness of lower limbs following an injury sustained during a road traffic accident. Clinically, the patient had a bilateral foot drop. On radiological evaluation, he was diagnosed to have L3 and L4 burst fractures with spinal canal occlusion. He underwent posterior stabilization from L2-L5 and decompression at the L3-L4 level. At one-year follow-up, the patient was pain-free with complete neurological recovery. Contiguous lumbar spine burst fractures are very rare in occurrence. Though burst fractures are managed surgically to provide stability, the surgical approaches depend on the individual fracture pattern, degree of spinal canal occlusion, and neurological status.
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Affiliation(s)
- Sai Preeth
- Department of Orthopaedics and Traumatology, SRM Medical College Hospital and Research Centre, Chennai, IND
| | - Vijayanand B
- Department of Orthopaedics and Traumatology, SRM Medical College Hospital and Research Centre, Chennai, IND
| | - Rishab C
- Department of Orthopaedics and Traumatology, SRM Medical College Hospital and Research Centre, Chennai, IND
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27
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Zhang J, Ye Z, Mao Y. Factors associated with loss of vertebral height and kyphosis correction after intermediate screws in short segment pedicular fixation for type-A fractures of the thoracolumbar spine: A retrospective study. Medicine (Baltimore) 2024; 103:e38343. [PMID: 39259126 PMCID: PMC11142796 DOI: 10.1097/md.0000000000038343] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/08/2023] [Revised: 04/25/2024] [Accepted: 05/02/2024] [Indexed: 09/12/2024] Open
Abstract
In this article, we attempted to identify risk factors affecting the loss of vertebral height and kyphosis correction on type A thoracolumbar fractures. Patients with type A thoracolumbar fractures who underwent short segments with intermediate screws at the fracture level management between 2017 and 2022 were included in this study. Clinical factors including patients' demographic characteristics (age, sex), history (smoking, hypertension and/or diabetes), value of height/kyphosis correction, the thoracolumbar injury classification and severity score (TLICS), the load sharing classification (LSC) scores and bone mineral density were collected. Correlation coefficient, simple linear regression analysis and multivariate regression analysis were performed to identify the clinical factors associated with the loss of vertebral height/kyphosis correction. Finally, 166 patients were included in this study. The mean height and kyphosis correction were 21.8% ± 7.5% and 9.9° ± 3.8°, respectively, the values of the loss were 6.5% ± 4.0% and 3.9° ± 1.9°, respectively. Simple linear regression analysis and multivariate regression analysis showed that age, value of height correction, LSC scores and bone mineral density were significantly associated with the loss of vertebral height and kyphosis correction (P < .01) We could draw the conclusion that patients with older age, lower bone mineral density, higher LSC scores and diabetes are at higher risk of vertebral height and kyphosis correction loss increase. For these patients, appropriate clinical measures such as long segment fixation, control of blood glucose, and increase of bone density must be taken to reduce the loss of correction.
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Affiliation(s)
- Junchao Zhang
- Department of Orthopaedics, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, Quzhou, Zhejiang Province, China
| | - Zhou Ye
- Department of Orthopaedics, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, Quzhou, Zhejiang Province, China
| | - Yi Mao
- Department of Orthopaedics, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, Quzhou, Zhejiang Province, China
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Korovessis P, Syrimpeis V, Korovesis A. Is open anterior advantageous to posterior decompression and reconstruction in fresh A 3 to C 3/AO type thoracolumbar junction fractures? A systematic review. Expert Rev Med Devices 2024; 21:411-425. [PMID: 38590235 DOI: 10.1080/17434440.2024.2341109] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/07/2024] [Accepted: 04/05/2024] [Indexed: 04/10/2024]
Abstract
INTRODUCTION Surgical outcomes of open anterior and open posterior approaches, for thoracolumbar A3 to C3/AO type fractures, are compared. METHODS A PubMed search was conducted from 1990 to 2024 related to anterior, posterior, and combined approaches. Inclusion criteria: Fresh traumatic T10 to L2 fractures, age ≥13 years, ≥10 cases, minimum follow-up 6 months. Exclusion criteria: Cadaveric studies, pathological fractures, reviews, thoracoscopy-assisted, mini-open lateral (MOLA) and minimal invasive anterior or posterior approaches. Coleman Methodology Scores (CMS) (modified for spinal trauma) indicated potential selection bias in the selected studies. PRISMA guidelines were adapted. RESULTS Nineteen studies with 847 participants were selected. The average CMS quality score was fair. The anterior approach, although it better decompresses the compromised spinal canal, it is also associated with increased surgical complications compared to the posterior approach. The neurological outcome, the loss of correction and the reoperation rate, were similar to both approaches. This systematic review favors posterior approach. CONCLUSIONS The anterior approach is demanding and is associated with a higher rate of surgical complications compared to the posterior approach. The limitations of the selected studies included inconsistence in the: 1) approaches selection, 2) classifications of the fracture types and the neurological status and 3) variety of instrumentations used. PROSPERO ID CRD42023484222.
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Affiliation(s)
- P Korovessis
- Orthopedics, General Hospital Patras Greece, Patras, Greece
| | - Vasileios Syrimpeis
- Electrical and Computer Engineering, University of the Peloponnese School of Engineering, Patras, Greece
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Sedighim S, Sargent B, Grigorian A, Grabar C, Macherla AR, Oh M, Lee YP, Scolaro J, Chen J, Nahmias J. Neurosurgery compared to orthopedic spine consultation: A single level I trauma center experience. BRAIN & SPINE 2024; 4:102808. [PMID: 38618229 PMCID: PMC11010962 DOI: 10.1016/j.bas.2024.102808] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 10/19/2023] [Revised: 02/26/2024] [Accepted: 04/04/2024] [Indexed: 04/16/2024]
Abstract
Introduction Both Orthopedic Surgery (OS) and Neurosurgery (NS) perform spine surgery in the setting of trauma. However, it is unknown whether outcomes differ between these specialties. This study compares management and outcomes for vertebral fractures between NS and OS, hypothesizing similar operation rate, length of stay (LOS), and readmission. Research question Do outcomes differ between NS and OS in the management of vertebral fractures following trauma? Methods A retrospective single-center study was conducted on adult patients with cervical, thoracic, lumbar, and sacral fractures treated at a single trauma center, where no standardized pathway exists across NS and OS. Patients were compared for injury profile, diagnostic imaging, and operative techniques as well as LOS, mortality, and complications. Results A total of 630 vertebral fracture patients (OS:350 (55.6%); NS:280 (44.4%)) were included. NS utilized magnetic resonance imaging (MRI) more commonly (36.4% vs. 22.6%, p < 0.001). NS patients more often underwent operation (13.2% vs. 7.4%, p = 0.016) despite similar fracture number and severity (p > 0.05). Post-operative complications, LOS, and readmission rates were similar between cohorts (p > 0.05). Discussion and conclusion Despite similar injury profiles, NS had higher rates of MRI usage and operative interventions in the context of traumatic spine fractures. Despite differences in management, major clinical outcomes were similar between NS and OS. However, we do call for further standardization of evaluation and treatment of patients based on established algorithms from such as the AOSpine Thoracolumbar Spine Injury Classification System (ATLICS).
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Affiliation(s)
- Shaina Sedighim
- Division of Trauma, Burns, And Surgical Critical Care, Department of Surgery, University of California, Irvine, Orange, CA, USA
| | - Brynn Sargent
- Division of Trauma, Burns, And Surgical Critical Care, Department of Surgery, University of California, Irvine, Orange, CA, USA
| | - Areg Grigorian
- Division of Trauma, Burns, And Surgical Critical Care, Department of Surgery, University of California, Irvine, Orange, CA, USA
| | - Christina Grabar
- Division of Trauma, Burns, And Surgical Critical Care, Department of Surgery, University of California, Irvine, Orange, CA, USA
| | - Anvesh R. Macherla
- Division of Trauma, Burns, And Surgical Critical Care, Department of Surgery, University of California, Irvine, Orange, CA, USA
| | - Michael Oh
- Department of Neurosurgery, University of California, Irvine, Orange, CA, USA
| | - Yu-Po Lee
- Department of Orthopedic Surgery, University of California, Irvine, Orange, CA, USA
| | - John Scolaro
- Department of Orthopedic Surgery, University of California, Irvine, Orange, CA, USA
| | - Jefferson Chen
- Department of Neurosurgery, University of California, Irvine, Orange, CA, USA
| | - Jeffry Nahmias
- Division of Trauma, Burns, And Surgical Critical Care, Department of Surgery, University of California, Irvine, Orange, CA, USA
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Aly MM, Soliman Y, Elemam RA, Pizones J, Alzahrani A, Elwatidy S. How frequently MRI modifies thoracolumbar fractures' classification or decision-making? A systematic review and meta-analysis. EUROPEAN SPINE JOURNAL : OFFICIAL PUBLICATION OF THE EUROPEAN SPINE SOCIETY, THE EUROPEAN SPINAL DEFORMITY SOCIETY, AND THE EUROPEAN SECTION OF THE CERVICAL SPINE RESEARCH SOCIETY 2024; 33:1540-1549. [PMID: 38342842 DOI: 10.1007/s00586-023-08087-4] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 07/31/2023] [Revised: 07/31/2023] [Accepted: 12/05/2023] [Indexed: 02/13/2024]
Abstract
PURPOSE To provide the first meta-analysis of the impact of magnetic resonance imaging (MRI) on thoracolumbar fractures (TLFs) classification and decision-making. METHODS A systematic review was conducted following PRISMA guidelines. We searched PubMed, Scopus, Cochrane, and Web of Science from inception to June 30, 2023 for studies evaluating the change in TLFs classification and treatment decisions after MRI. The studies extracted key findings, objectives, and patient population. A meta-analysis was performed for the pooled frequency of change in AO fracture classification or treatment decisions from surgical to conservative or vice versa after MRI. RESULTS This meta-analysis included four studies comprising 554 patients. The pooled frequency of change in TLFs classification was 17% (95% CI 9-31%), and treatment decision was 22% (95% CI 11-40%). An upgrade from type A to type B was reported in 15.7% (95% CI 7.2-30.6%), and downgrading type B to type A in 1.2% (95% CI 0.17-8.3%). A change from conservative to surgery recommendation of 17% (95% CI 5.0-43%) was higher than a change from surgery to conservative 2% (95% CI 1-34%). CONCLUSIONS MRI can significantly change the thoracolumbar classification and decision-making, primarily due to upgrading type A to type B fractures and changing from conservative to surgery, respectively. These findings suggest that MRI could change decision-making sufficiently to justify its use for TLFs. Type A subtypes, indeterminate PLC status, and spine regions might help to predict a change in TLFs' classification. However, more studies are needed to confirm the association of these variables with changes in treatment decisions to set the indications of MRI in neurologically intact patients with TLFs. An interactive version of our analysis can be accessed from here: https://databoard.shinyapps.io/mri_spine/ .
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Affiliation(s)
- Mohamed M Aly
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, P.O Box 54146, 11514, Riyadh, Saudi Arabia.
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt.
| | | | | | - Javier Pizones
- Unidad de Columna, Hospital Universitario La Paz, Madrid, Spain
| | - Ahmed Alzahrani
- Department of Neurosurgery, Security Forces Hospital, Riyadh, Saudi Arabia
| | - Sherif Elwatidy
- Division of Neurosurgery, Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia
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Aly MM, Abdelwahab OA, Atteya MME, Al-Shoaibi AM. How does vertical laminar fracture impact the decision-making in thoracolumbar fractures? A systematic scoping review and meta-analysis. EUROPEAN SPINE JOURNAL : OFFICIAL PUBLICATION OF THE EUROPEAN SPINE SOCIETY, THE EUROPEAN SPINAL DEFORMITY SOCIETY, AND THE EUROPEAN SECTION OF THE CERVICAL SPINE RESEARCH SOCIETY 2024; 33:1556-1573. [PMID: 38430400 DOI: 10.1007/s00586-024-08140-w] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 08/13/2023] [Revised: 01/05/2024] [Accepted: 01/11/2024] [Indexed: 03/03/2024]
Abstract
OBJECTIVE Although vertical laminar fracture (VLF) is generally considered a severity marker for thoracolumbar fractures (TLFs), its exact role in decision-making has never been established. This scoping review aims to synthesize the research on VLF's role in the decision-making of TLFs. METHODS A systematic review was conducted following PRISMA guidelines. We searched PubMed, Scopus, and Web of Science from inception to June 11, 2023, for studies examining the association of VLF in thoracolumbar fractures with dural lacerations, neurological deficits, radiographic parameters, or treatment outcomes. Additionally, experimental studies that analyze the biomechanics of burst fractures with VLF were included. The studies extracted key findings, objectives, and patient population. A meta-analysis was performed for the association of VLF with dural laceration and neurological deficit, and ORs were pooled with a 95% confidence interval (CI). RESULTS Twenty-eight studies were included in this systematic review, encompassing 2021 patients, and twelve were included in the meta-analysis. According to the main subject of the study, the association of VLF with a dural laceration (n = 14), neurological deficit (n = 4), radiographic parameters (n = 3), thoracolumbar fracture classification (n = 2), and treatment outcome (n = 2). Seven studies with a total of 1010 patients reported a significant association between VLF and neurological deficit (OR = 7.35, 95% CI [3.97, 14.25]; P < 0.001). The pooled OR estimates for VLF predicting dural lacerations were 7.75, 95% CI [2.41, 24.87]; P < 0.001). CONCLUSION VLF may have several important diagnostic and therapeutic implications in managing TLFs. VLF may help to distinguish AO type A3 from A4 fractures. VLF may help to predict preoperatively the occurrence of dural laceration, thereby choosing the optimal surgical strategy. Clinical and biomechanical data suggest VLF may be a valuable modifier to guide the decision-making in burst fractures; however, more studies are needed to confirm its prognostic importance regarding treatment outcomes.
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Affiliation(s)
- Mohamed M Aly
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt.
- Department of Neurosurgery, Prince Mohamed Ben Abdulaziz Hospital, P.O Box 54146, 11514, Riyadh, Saudi Arabia.
| | | | | | - Abdulbaset M Al-Shoaibi
- Department of Diagnostic Radiology, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia
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Choovongkomol K, Piyapromdee U, Thepjung S, Tanaviriyachai T, Jongkittanakul S, Sudprasert W. Comparative Outcomes of Percutaneous and Conventional Open Pedicle Screw Fixation for Single-level Thoracolumbar Spine Injury: Randomised Controlled Trial. Malays Orthop J 2024; 18:106-115. [PMID: 38638653 PMCID: PMC11023354 DOI: 10.5704/moj.2403.014] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/09/2023] [Accepted: 10/08/2023] [Indexed: 04/20/2024] Open
Abstract
Introduction To compare post-operative outcomes of percutaneous pedicle screw fixation (PPSF) vs open pedicle screw fixation (OPSF) in patients with thoracolumbar spine fractures with no neurological deficits. Materials and methods In a randomised controlled trial, patients received short-segment fixation with intermediate screws. We assessed post-operative back pain (Visual Analog Scale or VAS), blood loss, operative/fluoroscopy times, radiographic parameters, and oswestry disability index (ODI) scores at 1, 2, 3, 6, 9, and 12 months. Results Between January 2018 and October 2019, 31 patients received PPSF and 30 OPSF. Mean intra-operative blood loss was 66.45 (±44.29) ml for PPSF vs 184.83 (±128.36) ml for OPSF (p<0.001). Fluoroscopy time averaged 2.36 (±0.76) minutes for PPSF vs 0.58 (±0.51) minutes for OPSF (p<0.001). No significant differences existed in operative time or post-operative VAS scores. Radiographic parameters (kyphosis angle and vertebral height ratios) didn't significantly differ post-operatively or at 12 months. However, ODI scores differed significantly at 6 months (p=0.025), with no difference at 12 months. Conclusion In this trial, PPSF was comparable to OPSF in improving ODI scores at 12 months but showed earlier improvement at 6 months and reduced blood loss. Radiographic outcomes remained similar between groups over 12 months.
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Affiliation(s)
- K Choovongkomol
- Department of Orthopedic Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand
| | - U Piyapromdee
- Department of Orthopedic Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand
| | - S Thepjung
- Department of Orthopedic Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand
| | - T Tanaviriyachai
- Department of Orthopedic Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand
| | - S Jongkittanakul
- Department of Orthopedic Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand
| | - W Sudprasert
- Department of Orthopedic Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand
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Avila MJ, Dumont TM, Ganapathy V, Hurlbert RJ. Utility of Magnetic Resonance Imaging for Ligamentous Injury in Cervical Spine Trauma: A 2-Year Consecutive Case Cohort. World Neurosurg 2024; 183:e339-e344. [PMID: 38143031 DOI: 10.1016/j.wneu.2023.12.098] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/24/2023] [Revised: 12/17/2023] [Accepted: 12/18/2023] [Indexed: 12/26/2023]
Abstract
BACKGROUND Magnetic resonance imaging (MRI) is increasingly used as an adjunct to spinal soft tissue evaluation in cervical spine (C-spine) trauma; however, the utility of this information remains controversial. In this consecutive observational study, we reviewed the utility of MRI in patients with C-spine trauma. METHODS We identified patients in real time over a 2-year period as they presented to our level 1 trauma center for C-spine computed tomography (CT) scan followed by MRI. MRI was obtained by the trauma team prior to the spine service consultation if (1) they were unable to clear the C-spine according to protocol or (2) if the on-call radiologist reported a concern for ligamentous integrity from the CT findings. RESULTS Thirty-three patients, including 19 males (58%) and 14 females, with a mean age of 54 years, were referred to the spine service for concerns of ligamentous instability. The most common mechanisms of injury were motor vehicle accidents (n = 13) and falls (n = 11). MRI demonstrated ligamentous signal change identified by the radiologist as potentially unstable in all patients. Fifteen patients (45%) had multiple C-spine ligaments affected. The interspinous ligament was involved most frequently (28%), followed by the ligamentum flavum (21%) and supraspinous ligament (15%). All patients underwent dynamic upright C-spine X-rays that were interpreted by both the ordering surgeon and radiologist. There was no evidence of instability in any patient; concurrence between X-ray interpretation was 100%. The cervical collar was successfully removed in all cases. No patients required late surgical intervention, and there were no return visits to the emergency department of a spinal nature. CONCLUSIONS MRI signal change within the ligaments of the C-spine should be interpreted with caution in the setting of trauma. To physicians less familiar with spinal biomechanics, MRI findings may be perceived in an inadvertently alarming manner. Bony alignment and, when indicated, dynamic upright X-rays remain the gold standard for evaluating the ligamentous integrity of the C-spine.
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Affiliation(s)
- Mauricio J Avila
- Department of Neurosurgery, Banner University Medical Center, University of Arizona, Tucson, AZ, USA
| | - Travis M Dumont
- Department of Neurosurgery, Banner University Medical Center, University of Arizona, Tucson, AZ, USA
| | - Venkat Ganapathy
- Department of Orthopedic Surgery, Banner University Medical Center, University of Arizona, Tucson, AZ, USA
| | - R John Hurlbert
- Department of Neurosurgery, Banner University Medical Center, University of Arizona, Tucson, AZ, USA.
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Dandurand C, Fallah N, Öner CF, Bransford RJ, Schnake K, Vaccaro AR, Benneker LM, Vialle E, Schroeder GD, Rajasekaran S, El-Skarkawi M, Kanna RM, Aly M, Holas M, Canseco JA, Muijs S, Popescu EC, Tee JW, Camino-Willhuber G, Joaquim AF, Keynan O, Chhabra HS, Bigdon S, Spiegel U, Dvorak MF. Predictive Algorithm for Surgery Recommendation in Thoracolumbar Burst Fractures Without Neurological Deficits. Global Spine J 2024; 14:56S-61S. [PMID: 38324597 PMCID: PMC10867536 DOI: 10.1177/21925682231203491] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/09/2024] Open
Abstract
STUDY DESIGN Predictive algorithm via decision tree. OBJECTIVES Artificial intelligence (AI) remain an emerging field and have not previously been used to guide therapeutic decision making in thoracolumbar burst fractures. Building such models may reduce the variability in treatment recommendations. The goal of this study was to build a mathematical prediction rule based upon radiographic variables to guide treatment decisions. METHODS Twenty-two surgeons from the AO Knowledge Forum Trauma reviewed 183 cases from the Spine TL A3/A4 prospective study (classification, degree of certainty of posterior ligamentous complex (PLC) injury, use of M1 modifier, degree of comminution, treatment recommendation). Reviewers' regions were classified as Europe, North/South America and Asia. Classification and regression trees were used to create models that would predict the treatment recommendation based upon radiographic variables. We applied the decision tree model which accounts for the possibility of non-normal distributions of data. Cross-validation technique as used to validate the multivariable analyses. RESULTS The accuracy of the model was excellent at 82.4%. Variables included in the algorithm were certainty of PLC injury (%), degree of comminution (%), the use of M1 modifier and geographical regions. The algorithm showed that if a patient has a certainty of PLC injury over 57.5%, then there is a 97.0% chance of receiving surgery. If certainty of PLC injury was low and comminution was above 37.5%, a patient had 74.2% chance of receiving surgery in Europe and Asia vs 22.7% chance in North/South America. Throughout the algorithm, the use of the M1 modifier increased the probability of receiving surgery by 21.4% on average. CONCLUSION This study presents a predictive analytic algorithm to guide decision-making in the treatment of thoracolumbar burst fractures without neurological deficits. PLC injury assessment over 57.5% was highly predictive of receiving surgery (97.0%). A high degree of comminution resulted in a higher chance of receiving surgery in Europe or Asia vs North/South America. Future studies could include clinical and other variables to enhance predictive ability or use machine learning for outcomes prediction in thoracolumbar burst fractures.
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Affiliation(s)
- Charlotte Dandurand
- Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada
| | - Nader Fallah
- Praxis Spinal Cord Institute, Vancouver, BC, Canada
- Department of Medicine, University of British Columbia, Koerner Pavilion, UBC Hospital, Vancouver, BC, Canada
| | - Cumhur F Öner
- University Medical Centers, Utrecht, the Netherlands
| | - Richard J Bransford
- Department of Orthopaedics and Sports Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
| | - Klaus Schnake
- Center for Spinal and Scoliosis Surgery, Department of Orthopedics and Traumatology, Paracelsus Private Medical University Nuremberg, Nuremberg, Germany
| | - Alexander R Vaccaro
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Lorin M Benneker
- Spine Unit, Sonnenhof Spital, University of Bern, Bern, Switzerland
| | - Emiliano Vialle
- Cajuru Hospital, Catholic University of Paraná, Curitiba, Brazil
| | - Gregory D Schroeder
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | | | - Mohammad El-Skarkawi
- Department of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt
| | - Rishi M Kanna
- Spine Department of Orthopaedics and Spine Surgery, Ganga Hospital, Coimbatore, India
| | - Mohamed Aly
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabi
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt
| | - Martin Holas
- Klinika Úrazovej Chirurgie SZU a FNsP F.D.Roosevelta, Banská Bystrica, Slovakia
| | - Jose A Canseco
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Sander Muijs
- University Medical Centers, Utrecht, the Netherlands
| | | | - Jin Wee Tee
- Department of Neurosurgery, National Trauma Research Institute (NTRI), The Alfred Hospital, Melbourne, VIC, Australia
| | - Gaston Camino-Willhuber
- Orthopaedic and Traumatology Department, Institute of Orthopedics "Carlos E. Ottolenghi" Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
| | - Andrei Fernandes Joaquim
- Neurosurgery Division, Department of Neurology, State University of Campinas, Campinas-Sao Paulo, Brazil
| | - Ory Keynan
- Rambam Health Care Campus, Haifa, Israel
| | | | - Sebastian Bigdon
- Department of Orthopaedic Surgery and Traumatology, Inselspital, University Hospital, University of Bern, Bern, Switzerland
| | - Ulrich Spiegel
- Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University of Leipzig, Leipzig, Germany
| | - Marcel F Dvorak
- Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada
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Dvorak MF, Öner CF, Schnake K, Dandurand C, Muijs S. From Radiographic Evaluation to Treatment Decisions in Neurologically Intact Patients With Thoraco-lumbar Burst Fractures. Global Spine J 2024; 14:4S-7S. [PMID: 37991870 PMCID: PMC10867528 DOI: 10.1177/21925682231216584] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/24/2023] Open
Abstract
We propose that the key to improving care for these patients is to truly understand the processes that take place from the interpretation of radiographic findings, through the assessment of the severity of various injuries, to inclusion within a classification category and finally to selecting a specific treatment.
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Canseco JA, Paziuk T, Schroeder GD, Dvorak MF, Öner CF, Benneker LM, Vialle E, Rajasekaran S, El-Sharkawi M, Bransford RJ, Kanna RM, Holas M, Muijs S, Popescu EC, Dandurand C, Tee JW, Camino-Willhuber G, Aly MM, Joaquim AF, Keynan O, Chhabra HS, Bigdon S, Spiegl UJ, Schnake K, Vaccaro AR. Interobserver Reliability in the Classification of Thoracolumbar Fractures Using the AO Spine TL Injury Classification System Among 22 Clinical Experts in Spine Trauma Care. Global Spine J 2024; 14:17S-24S. [PMID: 38324600 PMCID: PMC10867533 DOI: 10.1177/21925682231202371] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/09/2024] Open
Abstract
STUDY DESIGN Reliability study utilizing 183 injury CT scans by 22 spine trauma experts with assessment of radiographic features, classification of injuries and treatment recommendations. OBJECTIVES To assess the reliability of the AOSpine TL Injury Classification System (TLICS) including the categories within the classification and the M1 modifier. METHODS Kappa and Intraclass correlation coefficients were produced. Associations of various imaging characteristics (comminution, PLC status) and treatment recommendations were analyzed through regression analysis. Multivariable logistic regression modeling was used for making predictive algorithms. RESULTS Reliability of the AO Spine TLICS at differentiating A3 and A4 injuries (N = 71) (K = .466; 95% CI .458 - .474; P < .001) demonstrated moderate agreement. Similarly, the average intraclass correlation coefficient (ICC) amongst A3 and A4 injuries was excellent (ICC = .934; 95% CI .919 - .947; P < .001) and the ICC between individual measures was moderate (ICC = .403; 95% CI .351 - .461; P < .001). The overall agreement on the utilization of the M1 modifier amongst A3 and A4 injuries was fair (K = .161; 95% CI .151 - .171; P < .001). The ICC for PLC status in A3 and A4 injuries averaged across all measures was excellent (ICC = .936; 95% CI .922 - .949; P < .001). The M1 modifier suggests respondents are nearly 40% more confident that the PLC is injured amongst all injuries. The M1 modifier was employed at a higher frequency as injuries were classified higher in the classification system. CONCLUSIONS The reliability of surgeons differentiating between A3 and A4 injuries in the AOSpine TLICS is substantial and the utilization of the M1 modifier occurs more frequently with higher grades in the system.
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Affiliation(s)
- Jose A Canseco
- Department of Orthopaedic Surgery, Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA
| | - Taylor Paziuk
- Department of Orthopaedic Surgery, Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA
| | - Gregory D Schroeder
- Department of Orthopaedic Surgery, Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA
| | - Marcel F Dvorak
- Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, Canada
| | - Cumhur F Öner
- University Medical Centers, Utrecht, the Netherlands
| | - Lorin M Benneker
- Spine Unit, Sonnenhof Spital, University of Bern, Bern, Switzerland
| | - Emiliano Vialle
- Cajuru Hospital, Catholic University of Paraná, Curitiba, Brazil
| | | | - Mohammad El-Sharkawi
- Department of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University Medical School, Assiut, Egypt
| | - Richard J Bransford
- Department of Orthopaedics and Sports Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
| | - Rishi M Kanna
- Department of Orthopaedics and Spine Surgery, Ganga Hospital, Coimbatore, India
| | - Martin Holas
- Klinika Úrazovej Chirurgie SZU a FNsP F.D.Roosevelta, Banská Bystrica, Slovakia
| | - Sander Muijs
- University Medical Centers, Utrecht, the Netherlands
| | | | - Charlotte Dandurand
- Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, Canada
| | - Jin W Tee
- Department of Neurosurgery, National Trauma Research Institute (NTRI), The Alfred Hospital, Melbourne, VIC, Australia
| | - Gaston Camino-Willhuber
- Orthopaedic and Traumatology Department, Institute of Orthopedics "Carlos E. Ottolenghi" Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
| | - Mohamed M Aly
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabi
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt
| | - Andrei Fernandes Joaquim
- Neurosurgery Division, Department of Neurology, State University of Campinas, Campinas-Sao Paulo, Brazil
| | - Ory Keynan
- Rambam Health Care Campus, Haifa, Israel
| | | | - Sebastian Bigdon
- Department of Orthopaedic Surgery and Traumatology, Inselspital, University Hospital, University of Bern, Bern, Switzerland
| | - Ulrich J Spiegl
- Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University of Leipzig, Leipzig, Germany
| | - Klaus Schnake
- Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien Erlangen, Erlangen, Germany
- Department of Orthopedics and Traumatology, Paracelsus Private Medical University Nuremberg, Nuremberg, Germany
| | - Alexander R Vaccaro
- Department of Orthopaedic Surgery, Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA
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Camino-Willhuber G, Bigdon S, Dandurand C, Dvorak MF, Öner CF, Schnake K, Muijs S, Benneker LM, Vialle E, Tee JW, Keynan O, Chhabra HS, Joaquim AF, Popescu EC, Canseco JA, Holas M, Kanna RM, Aly MM, Fallah N, Schroeder GD, Spiegl U, El-Skarkawi M, Bransford RJ, Rajasekaran S, Vaccaro AR. Expert Opinion, Real-World Classification, and Decision-Making in Thoracolumbar Burst Fractures Without Neurologic Deficits? Global Spine J 2024; 14:49S-55S. [PMID: 38324602 PMCID: PMC10867532 DOI: 10.1177/21925682231194456] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/09/2024] Open
Abstract
STUDY DESIGN Retrospective analysis of prospectively collected data. OBJECTIVES To compare decision-making between an expert panel and real-world spine surgeons in thoracolumbar burst fractures (TLBFs) without neurological deficits and analyze which factors influence surgical decision-making. METHODS This study is a sub-analysis of a prospective observational study in TL fractures. Twenty two experts were asked to review 183 CT scans and recommend treatment for each fracture. The expert recommendation was based on radiographic review. RESULTS Overall agreement between the expert panel and real-world surgeons regarding surgery was 63.2%. In 36.8% of cases, the expert panel recommended surgery that was not performed in real-world scenarios. Conversely, in cases where the expert panel recommended non-surgical treatment, only 38.6% received non-surgical treatment, while 61.4% underwent surgery. A separate analysis of A3 and A4 fractures revealed that expert panel recommended surgery for 30% of A3 injuries and 68% of A4 injuries. However, 61% of patients with both A3 and A4 fractures received surgery in the real world. Multivariate analysis demonstrated that a 1% increase in certainty of PLC injury led to a 4% increase in surgery recommendation among the expert panel, while a .2% increase in the likelihood of receiving surgery in the real world. CONCLUSION Surgical decision-making varied between the expert panel and real-world treating surgeons. Differences appear to be less evident in A3/A4 burst fractures making this specific group of fractures a real challenge independent of the level of expertise.
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Affiliation(s)
- Gaston Camino-Willhuber
- Institute of Orthopedics "Carlos E. Ottolenghi", Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
| | - Sebastian Bigdon
- Department of Orthopaedic Surgery and Traumatology, Inselspital, University Hospital, University of Bern, Bern, Switzerland
| | - Charlotte Dandurand
- Combined Neurosurgical and Orthopaedic Spine Program, Department of Orthopaedic Surgery, University of British Columbia, Vancouver, BC, Canada
| | - Marcel F Dvorak
- Combined Neurosurgical and Orthopaedic Spine Program, Department of Orthopaedic Surgery, University of British Columbia, Vancouver, BC, Canada
| | - Cumhur F Öner
- University Medical Centers, Utrecht, The Netherlands
| | - Klaus Schnake
- Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien, Erlangen, Germany
- Department of Orthopedics and Traumatology, Paracelsus Private Medical University Nuremberg, Nuremberg, Germany
| | - Sander Muijs
- University Medical Centers, Utrecht, The Netherlands
| | - Lorin M Benneker
- Spine Unit, Sonnenhof Spital, University of Bern, Bern, Switzerland
| | - Emiliano Vialle
- Cajuru Hospital, Catholic University of Paraná, Curitiba, Brazil
| | - Jin W Tee
- Department of Neurosurgery, National Trauma Research Institute (NTRI), Melbourne, VIC, Australia
| | - Ory Keynan
- Rambam Health Care Campus, Haifa, Israel
| | - Harvinder S Chhabra
- Department of Spine Service, Indian Spinal Injuries Centre, Sector C, Vasant Kunj, New Delhi, India
| | - Andrei F Joaquim
- Department of Neurology, State University of Campinas, Campinas-Sao Paulo, Brazil
| | | | - Jose A Canseco
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Martin Holas
- Klinika Úrazovej Chirurgie SZU a FNsP F.D.Roosevelta, Banská Bystrica, Slovakia
| | - Rishi M Kanna
- Department of Orthopaedics and Spine Surgery, Ganga Hospital, Coimbatore, Tamil Nadu, India
| | - Mohamed M Aly
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabi
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt
| | - Nader Fallah
- Combined Neurosurgical and Orthopaedic Spine Program, Department of Orthopaedic Surgery, University of British Columbia, Vancouver, BC, Canada
| | - Gregory D Schroeder
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Ulrich Spiegl
- Klinik für Orthopädie, Unfallchirurgie und plastische Chirurgie, Universitätsklinik Leipzig, Leipzig, Germany
| | - Mohammad El-Skarkawi
- Department of Orthopaedic and Trauma Surgery, Assiut University Medical School, Assiut, Egypt
| | - Richard J Bransford
- Department of Orthopaedics and Sports Medicine, University of Washington Harborview Medical Center, Seattle, WA, USA
| | | | - Alexander R Vaccaro
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
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Kweh BTS, Tee JW, Dandurand C, Vaccaro AR, Lorin BM, Schnake K, Vialle E, Rajasekaran S, El-Skarkawi M, Bransford RJ, Kanna RM, Aly MM, Holas M, Canseco JA, Muijs S, Popescu EC, Camino-Willhuber G, Joaquim AF, Chhabra HS, Bigdon SF, Spiegel U, Dvorak M, Öner CF, Schroeder G. The AO Spine Thoracolumbar Injury Classification System and Treatment Algorithm in Decision Making for Thoracolumbar Burst Fractures Without Neurologic Deficit. Global Spine J 2024; 14:32S-40S. [PMID: 38324601 PMCID: PMC10867534 DOI: 10.1177/21925682231195764] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 02/09/2024] Open
Abstract
STUDY DESIGN Prospective Observational Study. OBJECTIVE To determine the alignment of the AO Spine Thoracolumbar Injury Classification system and treatment algorithm with contemporary surgical decision making. METHODS 183 cases of thoracolumbar burst fractures were reviewed by 22 AO Spine Knowledge Forum Trauma experts. These experienced clinicians classified the fracture morphology, integrity of the posterior ligamentous complex and degree of comminution. Management recommendations were collected. RESULTS There was a statistically significant stepwise increase in rates of operative management with escalating category of injury (P < .001). An excellent correlation existed between recommended expert management and the actual treatment of each injury category: A0/A1/A2 (OR 1.09, 95% CI 0.70-1.69, P = .71), A3/4 (OR 1.62, 95% CI 0.98-2.66, P = .58) and B1/B2/C (1.00, 95% CI 0.87-1.14, P = .99). Thoracolumbar A4 fractures were more likely to be surgically stabilized than A3 fractures (68.2% vs 30.9%, P < .001). A modifier indicating indeterminate ligamentous injury increased the rate of operative management when comparing type B and C injuries to type A3/A4 injuries (OR 39.19, 95% CI 20.84-73.69, P < .01 vs OR 27.72, 95% CI 14.68-52.33, P < .01). CONCLUSIONS The AO Spine Thoracolumbar Injury Classification system introduces fracture morphology in a rational and hierarchical manner of escalating severity. Thoracolumbar A4 complete burst fractures were more likely to be operatively managed than A3 fractures. Flexion-distraction type B injuries and translational type C injuries were much more likely to have surgery recommended than type A fractures regardless of the M1 modifier. A suspected posterior ligamentous injury increased the likelihood of surgeons favoring surgical stabilization.
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Affiliation(s)
- Barry T S Kweh
- National Trauma Research Institute, Melbourne, VIC, Australia
- Department of Neurosurgery, The Alfred Hospital, Melbourne, VIC, Australia
- Department of Neurosurgery, Royal Melbourne Hospital, Parkville, VIC, Melbourne
| | - Jin Wee Tee
- National Trauma Research Institute, Melbourne, VIC, Australia
- Department of Neurosurgery, The Alfred Hospital, Melbourne, VIC, Australia
- Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia
| | - Charlotte Dandurand
- Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada
| | - Alexander R Vaccaro
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Benneker M Lorin
- Spine Unit, Sonnenhof Spital, University of Bern, Bern, Switzerland
| | - Klaus Schnake
- Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien, Erlangen, Germany
- Department of Orthopedics and Traumatology, Paracelsus Private Medical University Nuremberg, Nuremberg, Germany
| | - Emiliano Vialle
- Cajuru Hospital, Catholic University of Paraná, Curitiba, Brazil
| | | | - Mohammad El-Skarkawi
- Department of Orthopaedic and Trauma Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt
| | - Richard J Bransford
- Department of Orthopaedics and Sports Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA
| | - Rishi M Kanna
- Department of Orthopaedics and Spine Surgery, Ganga Hospital, Coimbatore, India
| | - Mohamed M Aly
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabi
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt
| | - Martin Holas
- Klinika Úrazovej Chirurgie SZU a FNsP F.D.Roosevelta, Banská Bystrica, Slovakia
| | - Jose A Canseco
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
| | - Sander Muijs
- University Medical Centers, Utrecht, The Netherlands
| | | | - Gaston Camino-Willhuber
- Orthopaedic and Traumatology Department, Institute of Orthopedics "Carlos E. Ottolenghi" Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
| | - Andrei F Joaquim
- Neurosurgery Division, Department of Neurology, State University of Campinas, Campinas-Sao Paulo, Brazil
| | | | - Sebastian Frederick Bigdon
- Department of Orthopaedic Surgery and Traumatology, Inselspital, University Hospital, University of Bern, Bern, Switzerland
| | - Ulrich Spiegel
- Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University of Leipzig, Leipzig, Germany
| | - Marcel Dvorak
- Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada
| | - Cumhur F Öner
- University Medical Centers, Utrecht, The Netherlands
| | - Gregory Schroeder
- Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
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Han Y, Ma J, Zhang G, Huang L, Kang H. Percutaneous monoplanar screws versus hybrid fixed axial and polyaxial screws in intermediate screw fixation for traumatic thoracolumbar burst fractures: a case-control study. J Orthop Surg Res 2024; 19:85. [PMID: 38254136 PMCID: PMC10801944 DOI: 10.1186/s13018-024-04547-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/24/2023] [Accepted: 01/08/2024] [Indexed: 01/24/2024] Open
Abstract
BACKGROUND To compare the clinical and radiological outcomes of monoplanar screws (MSs) versus hybrid fixed axial and polyaxial screws (HSs) in percutaneous short-segment intermediate screw fixation (PSISF) for traumatic thoracolumbar burst fractures (TTBFs) in patients without neurologic impairment. METHODS A consecutive series of 100 patients with single-segment TTBFs and no neurologic impairment who underwent PSISF with 6 monoplanar screws (MS group) or correct were retrospectively enrolled. The demographic data, radiologic evaluation indicators, perioperative indicators and clinical assessment indicators were analysed between the MS group and HS group. RESULTS The demographic data and perioperative indicators were not significantly different in the two groups (P > 0.05). The postoperative anterior vertebral height ratio (AVHR), kyphosis Cobb angle (KCA), vertebral wedge angle (VWA) and spinal canal encroachment rate (SCER) were significantly improved in both groups (*P < 0.05). The MS group obtained better correction than the HS group in terms of improvement in the AVHR, KCA and VWA after surgery (*P < 0.05). At the last follow-up, the MS group had less correction loss of AVHR, KCA and VWA (*P < 0.05). The MS group presented greater improvement in the SCER at the last follow-up (*P < 0.05). The visual analogue scale (VAS) score and Oswestry Disability Index (ODI) score of all patients were significantly better postoperatively than those preoperatively (*P < 0.05), and the scores collected at each follow-up visit did not differ significantly between the two groups (P > 0.05). In the MS group, no internal fixation failure was observed during the follow-up period, but, in the HS group, two cases of internal fixation failure were observed at the last follow-up (one case of rod loosening and one case of screw breakage). CONCLUSIONS Both MSs and HSs fixation are effective treatments for TTBFs and have comparable clinical outcomes. In contrast, MSs fixation can improve the correction effect, better improve the SCER, and further reduce correction loss as well as reduce the incidence of instrumentation failure. Therefore, MSs fixation might be a better option for treating TTBFs in patients without neurological deficits.
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Affiliation(s)
- Yaozheng Han
- Medical College, Wuhan University of Science and Technology, Wuhan, 430065, Hubei, China
| | - Jun Ma
- Department of Orthopaedic, General Hospital of Central Theater Command, Wuhan, 430070, Hubei, China
| | - Guoquan Zhang
- Medical College, Hubei University of Medicine, Shiyan, 442000, Hubei, China
| | - Liangliang Huang
- Department of Orthopaedic, General Hospital of Central Theater Command, Wuhan, 430070, Hubei, China.
| | - Hui Kang
- Department of Orthopaedic, General Hospital of Central Theater Command, Wuhan, 430070, Hubei, China.
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Dietrich G, Richard R, Akiki A, Levy S, Maeder B. Thoracic spinous process nonunion as an unusual cause of back pain: a case report and review of the literature. J Med Case Rep 2024; 18:11. [PMID: 38167123 PMCID: PMC10762786 DOI: 10.1186/s13256-023-04109-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/04/2022] [Accepted: 08/01/2023] [Indexed: 01/05/2024] Open
Abstract
BACKGROUND Purely isolated spinous processes fractures are rare and are usually treated conservatively, although a few authors have reported cases of nonunion that ultimately required surgical resection. CASE PRESENTATION We present a case of an isolated T6 spinous process pseudoarthrosis that was treated by surgical resection of the tip of the spinous process. A 34-year-old Caucasian male patient was complaining of mid-thoracic back pain without neurologic impairment more than 2 years after an isolated spinous process fracture. Magnetic Resonance Imaging (MRI) and Single Photon Emission Computed Tomography (SPECT) revealed a nonunion. We performed a resection without further complication. CONCLUSION Although spinous process nonunions may in some cases be well tolerated, surgical resection appears to be a reliable option in case of persistent symptoms. This illustrated case shows the description of an isolated thoracic spinous process nonunion and its surgical treatment.
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Affiliation(s)
- Gilles Dietrich
- Orthopaedic Surgery and Traumatology Department, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
- Orthopaedic Surgery and Traumatology Department, Riviera-Chablais Hospital, Rennaz, Switzerland.
| | - Raphaël Richard
- Radiology Department, Riviera-Chablais Hospital, Rennaz, Switzerland
| | - Alain Akiki
- Orthopaedic Surgery and Traumatology Department, Riviera-Chablais Hospital, Rennaz, Switzerland
| | - Sebastien Levy
- Orthopaedic Surgery and Traumatology Department, Riviera-Chablais Hospital, Rennaz, Switzerland
| | - Benoit Maeder
- Orthopaedic Surgery and Traumatology Department, Riviera-Chablais Hospital, Rennaz, Switzerland
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Esipov AV, Antonov GI, Manukovsky VA, Kravtsov MN, Chmutin GE, Timonin SY, Danilov GV, Kelin AO. [Scoring system for unstable spinal gunshot wounds: the study protocol]. ZHURNAL VOPROSY NEIROKHIRURGII IMENI N. N. BURDENKO 2024; 88:56-61. [PMID: 39169582 DOI: 10.17116/neiro20248804156] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 08/23/2024]
Abstract
Morphology of injuries following gunshot wounds requires specific treatment approaches. Currently, there are no similar classifications for assessing fracture stability with subsequent tactical recommendations. Taking into account diagnostic limitations (contraindications for MRI due to implantable metal fragments, limitations of functional radiography of the spine in seriously injured patients), we make decisions considering CT data. In this study, we will determine severity of vertebral damage and effect of these damages on mechanical stability of spinal motion segments. In the future, CT-based assessment of inter-expert agreement will be performed. Finally, we will propose the scoring system for classification of spinal gunshot wounds. OBJECTIVE To present a research protocol for development of new scoring system for unstable spinal gunshot wounds based on inter-expert agreement assessment. MATERIAL AND METHODS To create a new tactical classification, we will distinguish and analyze clinical and CT data of patients with thoracolumbar spinal gunshot wounds. The Delphi method will be used to collaborate between several surgeons. A three-stage study will result a questionnaire (for 30 clinical cases). We will develop tactical scoring system and analyze statistical data (kappa). DISCUSSION Various classifications have been developed for closed spinal injuries. These systems describe the nature of injury and allow one to develop tactical decisions for further actions. Another mechanism of injuries following gunshot wounds does not allow the classification of closed injuries to be adequately applied in some cases. Indeed, spinal structures follow either direct passage of a wounding projectile through the spine or transferring the energy of this projectile in contrast to classical compression, distraction and rotational-translation mechanisms typical for closed trauma.
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Affiliation(s)
- A V Esipov
- Vishnevsky Central Military Clinical Hospital, Krasnogorsk, Russia
| | - G I Antonov
- Vishnevsky Central Military Clinical Hospital, Krasnogorsk, Russia
- Peoples' Friendship University of Russia, Moscow, Russia
| | - V A Manukovsky
- Vishnevsky Central Military Clinical Hospital, Krasnogorsk, Russia
- Branch of the Kirov Military Medical Academy in Moscow, Moscow, Russia
| | - M N Kravtsov
- Kirov Military Medical Academy, St. Petersburg, Russia
- Dzhanelidze St. Petersburg Research Institute for Emergency Care, St. Petersburg, Russia
- Mechnikov North-Western State Medical University, St. Petersburg, Russia
| | - G E Chmutin
- Peoples' Friendship University of Russia, Moscow, Russia
| | - S Yu Timonin
- Vishnevsky Central Military Clinical Hospital, Krasnogorsk, Russia
| | - G V Danilov
- Burdenko Neurosurgical Center, Moscow, Russia
| | - A O Kelin
- Peoples' Friendship University of Russia, Moscow, Russia
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Lim DJ. Surgical management of posterior ligament complex stripping in an adolescent spinal flexion distraction injury: A case report and literature review. Int J Surg Case Rep 2024; 114:109195. [PMID: 38151000 PMCID: PMC10800587 DOI: 10.1016/j.ijscr.2023.109195] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/10/2023] [Revised: 12/18/2023] [Accepted: 12/20/2023] [Indexed: 12/29/2023] Open
Abstract
INTRODUCTION Adolescent spinal injuries such as flexion-distraction injuries with posterior ligament complex (PLC) stripping require specialized management because of the unique interplay between injury mechanics and spinal growth. This case report sheds light on these rare occurrences and their management. PRESENTATION OF CASE An 11-year-old boy sustained spinal flexion-distraction injuries resulting in posterior ligament complex stripping following a passenger traffic accident. He underwent a meticulously planned surgical intervention involving urgent posterior fusion with pedicle screw fixation at the L1-2-3 levels and allograft bone grafting. This approach was chosen considering the unique challenges posed by his adolescent spinal anatomy and the nature of his injuries. Postoperative management included using thoracolumbar-sacral orthosis (TLSO), facilitating early ambulation and recovery. DISCUSSION The rarity of PLC stripping in adolescents underscores the importance of case studies for guiding care. This instance validates the surgical approach and highlights the importance of postoperative management with TLSO for early mobility and prevention of growth-related deformities. This case emphasizes the need for vigilant surgical and postoperative strategies in adolescent spinal injury management. CONCLUSION An early surgical approach complemented by strategic postoperative management, including the use of TLSO for early mobilization, is vital for the treatment of adolescent spinal injuries. Effective recovery and careful consideration of spinal growth are essential during treatment. Documenting such cases contributes to the body of knowledge necessary to enhance the care strategies for patients with similar injuries.
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Affiliation(s)
- Dong-Ju Lim
- Department of Orthopaedic Surgery, Seoul Spine Institute, Sanggye Paik Hospital, College of Medicine, Inje University, Republic of Korea.
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Aly MM, Al-Shoaibi AM, Abduraba Ali S, Al Fattani A, Eldawoody H. How Often Would MRI Change the Thoracolumbar Fracture Classification or Decision-Making Compared to CT Alone? Global Spine J 2024; 14:11-24. [PMID: 35382642 PMCID: PMC10676184 DOI: 10.1177/21925682221089579] [Citation(s) in RCA: 10] [Impact Index Per Article: 10.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/15/2022] Open
Abstract
STUDY DESIGN retrospective study of consecutive patients. OBJECTIVE to analyze the frequency of change in Thoracolumbar fractures (TLFs) classification or decision-making after MRI compared by CT alone. METHODS A retrospective review of 244 consecutive patients with acute TLFs (T1-L5) presented to a single level 1 trauma center between 2014 and 2021. Three and 4 reviewers independently classified all fractures according to AOSpine and AOSpine injury severity score (TLAOSIS) by CT then MRI, respectively. Posterior ligamentous complex Injury (PLC) was diagnosed on CT and MRI by ≥ 2 positive CT findings and Black stripe discontinuity. RESULTS MRI changed AO classification in 25/244 patients (10.2%, P < .0001) due to an 8.2% upgrade from type A to type B and a 2% downgrade from type B to type A. The addition of MRI changed TL AOSIS among the 3 treatment recommendation groups in 35/244 (19.7%, 95% CI [14.9%-25.2%]. The best predictor of upgrade from type A to type B and downgrade from type B to type A was a single positive CT finding and the presence of only 2 CT signs as opposed to ≥3 signs, respectively (P < .0001 P = .03, respectively). Thoracic fractures showed a significantly higher reclassification rate than thoracolumbar and low lumbar (20% vs 10% and 0%, respectively, P = .07). CONCLUSION using appropriate CT/MRI criteria for PLC injury, MRI changed the AOSpine classification by 10% and TLAOSIS based treatment by 19.7%. The best predictors of fracture reclassification by MRI were the number of positive CT findings and fracture level.
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Affiliation(s)
- Mohamed M. Aly
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt
| | - Abdulbaset M. Al-Shoaibi
- Department of Diagnostic Radiology, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia
| | - Saleh Abduraba Ali
- Department of Diagnostic Radiology, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia
| | - Areej Al Fattani
- Department of Biostatistics Epidemiology and Scientific computing, King Faisal Specialist Hospital and Research Hospital, Riyadh, Saudi Arabia
| | - Hany Eldawoody
- Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia
- Department of Neurosurgery, Mansoura University, Mansoura, Egypt
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Jo SW, Khil EK, Lee KY, Choi I, Yoon YS, Cha JG, Lee JH, Kim H, Lee SY. Deep learning system for automated detection of posterior ligamentous complex injury in patients with thoracolumbar fracture on MRI. Sci Rep 2023; 13:19017. [PMID: 37923853 PMCID: PMC10624679 DOI: 10.1038/s41598-023-46208-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/27/2023] [Accepted: 10/29/2023] [Indexed: 11/06/2023] Open
Abstract
This study aimed to develop a deep learning (DL) algorithm for automated detection and localization of posterior ligamentous complex (PLC) injury in patients with acute thoracolumbar (TL) fracture on magnetic resonance imaging (MRI) and evaluate its diagnostic performance. In this retrospective multicenter study, using midline sagittal T2-weighted image with fracture (± PLC injury), a training dataset and internal and external validation sets of 300, 100, and 100 patients, were constructed with equal numbers of injured and normal PLCs. The DL algorithm was developed through two steps (Attention U-net and Inception-ResNet-V2). We evaluate the diagnostic performance for PLC injury between the DL algorithm and radiologists with different levels of experience. The area under the curves (AUCs) generated by the DL algorithm were 0.928, 0.916 for internal and external validations, and by two radiologists for observer performance test were 0.930, 0.830, respectively. Although no significant difference was found in diagnosing PLC injury between the DL algorithm and radiologists, the DL algorithm exhibited a trend of higher AUC than the radiology trainee. Notably, the radiology trainee's diagnostic performance significantly improved with DL algorithm assistance. Therefore, the DL algorithm exhibited high diagnostic performance in detecting PLC injuries in acute TL fractures.
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Affiliation(s)
- Sang Won Jo
- Department of Radiology, Hallym University Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Republic of Korea
| | - Eun Kyung Khil
- Department of Radiology, Hallym University Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Republic of Korea.
- Department of Radiology, Fastbone Orthopedic Hospital, Hwaseong-si, Republic of Korea.
| | - Kyoung Yeon Lee
- Department of Radiology, Hallym University Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Republic of Korea
| | - Il Choi
- Department of Neurologic Surgery, Hallym University Dongtan Sacred Heart Hospital, Hwaseong-si, Republic of Korea
| | - Yu Sung Yoon
- Department of Radiology, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea
- Department of Radiology, Kyungpook National University Hospital, Daegu, Republic of Korea
| | - Jang Gyu Cha
- Department of Radiology, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea
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Gerges C, Raghavan A, Wright J, Shammassian B, Wright CH, Moore T. Cervical, thoracolumbar, and sacral spine trauma classifications: past, present, and future. Neurol Res 2023; 45:877-883. [PMID: 32758096 DOI: 10.1080/01616412.2020.1797373] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/29/2019] [Accepted: 07/14/2020] [Indexed: 10/23/2022]
Abstract
OBJECTIVE Traumatic spine injuries are a relatively common occurrence and are associated with functional impairment, loss of neurologic function, and spinal deformity. A number of spinal trauma classification systems have been developed with varying degrees of acceptance. This review provides a chronological overview of spinal trauma classification systems, with special consideration towards the benefits and pitfalls related to each. Cervical, thoracolumbar, and sacral trauma classification systems are discussed. METHODS A review of the literature was performed. Published articles that reported on bony spinal trauma classification systems were examined. No year exemptions were identified. The reference lists of all selected articles were screened for additional studies. Article inclusion and exclusion criteria were defined a priori. RESULTS A total of 20 classification systems were identified from years 1938-2017. Of these 20 classification systems, 6 were cervical, 11 were thoracolumbar and 3 were sacral. The modernization of bony spinal trauma classification has been characterized by the development of weighted scales that include injury morphology, integrity of associated ligamentous structures and neurologic status. CONCLUSION For widespread acceptance and adoption in the clinical setting, future spinal trauma scoring classification will need to remain simple, highly reproducible, and impart information with regard to clinical decision-making and prognosis that may be effectively communicated across each medical specialty involved in the care of these patients.
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Affiliation(s)
- Christina Gerges
- Case Western Reserve University School of Medicine, Cleveland, OH, USA
| | | | - James Wright
- Case Western Reserve University School of Medicine, Cleveland, OH, USA
- Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA
| | - Berje Shammassian
- Case Western Reserve University School of Medicine, Cleveland, OH, USA
- Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA
| | - Christina Huang Wright
- Case Western Reserve University School of Medicine, Cleveland, OH, USA
- Department of Neurological Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA
| | - Timothy Moore
- Department of Orthopaedics, MetroHealth Medical Center, Cleveland, OH, USA
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Karamian BA, Schroeder GD, Lambrechts MJ, Canseco JA, AO Spine Sacral Classification Group Members, Vialle EN, Rajasekaran S, Benneker LM, Dvorak MR, Kandziora F, Oner C, Schnake K, Kepler CK, Vaccaro AR. The Influence of Regional Differences on the Reliability of the AO Spine Sacral Injury Classification System. Global Spine J 2023; 13:2025-2032. [PMID: 35000410 PMCID: PMC10556908 DOI: 10.1177/21925682211068419] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/17/2022] Open
Abstract
STUDY DESIGN Global cross-sectional survey. OBJECTIVE To explore the influence of geographic region on the AO Spine Sacral Classification System. METHODS A total of 158 AO Spine and AO Trauma members from 6 AO world regions (Africa, Asia, Europe, Latin and South America, Middle East, and North America) participated in a live webinar to assess the reliability, reproducibility, and accuracy of classifying sacral fractures using the AO Spine Sacral Classification System. This evaluation was performed with 26 cases presented in randomized order on 2 occasions 3 weeks apart. RESULTS A total of 8320 case assessments were performed. All regions demonstrated excellent intraobserver reproducibility for fracture morphology. Respondents from Europe (k = .80) and North America (k = .86) achieved excellent reproducibility for fracture subtype while respondents from all other regions displayed substantial reproducibility. All regions demonstrated at minimum substantial interobserver reliability for fracture morphology and subtype. Each region demonstrated >90% accuracy in classifying fracture morphology and >80% accuracy in fracture subtype compared to the gold standard. Type C morphology (p2 = .0000) and A3 (p1 = .0280), B2 (p1 = .0015), C0 (p1 = .0085), and C2 (p1 =.0016, p2 =.0000) subtypes showed significant regional disparity in classification accuracy (p1 = Assessment 1, p2 = Assessment 2). Respondents from Asia (except in A3) and the combined group of North, Latin, and South America had accuracy percentages below the combined mean, whereas respondents from Europe consistently scored above the mean. CONCLUSIONS In a global validation study of the AO Spine Sacral Classification System, substantial reliability of both fracture morphology and subtype classification was found across all geographic regions.
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Affiliation(s)
- Brian A. Karamian
- Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA
| | | | | | - Jose A. Canseco
- Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA
| | - AO Spine Sacral Classification Group Members
- Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA
- Spine Surgery Group, Department of Orthopaedics, Cajuru University Hospital, Catholic University of Parana, Curitaba, Brazil
- Department of Orthopedics and Spine Surgery, Ganga Hospital, Coimbatore, India
- Department of Orthopaedic Surgery, Inselspital, University of Bern, Bern, Switzerland
- Division of Spine, University of British Columbia
- Unfallklinik Frankfurt am Main, Frankfurt, Germany
- Department of Orthopedic Surgery, University Medical Center, University of Utrecht, Utrecht, Netherlands
- Center for Spinal Surgery, Schön Klinik Nürnberg Fürth, Fürth, Germany
| | - Emiliano N. Vialle
- Spine Surgery Group, Department of Orthopaedics, Cajuru University Hospital, Catholic University of Parana, Curitaba, Brazil
| | | | - Lorin M. Benneker
- Department of Orthopaedic Surgery, Inselspital, University of Bern, Bern, Switzerland
| | | | | | - Cumhur Oner
- Department of Orthopedic Surgery, University Medical Center, University of Utrecht, Utrecht, Netherlands
| | - Klaus Schnake
- Center for Spinal Surgery, Schön Klinik Nürnberg Fürth, Fürth, Germany
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Blais M, Shahidi B, Anderson B, O'Brien E, Moltzen C, Iannacone T, Eastlack RK, Mundis GM. The influence of ligament biomechanics on proximal junctional kyphosis and failure in patients with adult spinal deformity. JOR Spine 2023; 6:e1277. [PMID: 37780835 PMCID: PMC10540824 DOI: 10.1002/jsp2.1277] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/15/2023] [Revised: 07/04/2023] [Accepted: 08/03/2023] [Indexed: 10/03/2023] Open
Abstract
Purpose It is unknown whether the biomechanics of the posterior ligamentous complex (PLC) are impaired in individuals undergoing surgery for adult spinal deformity (ASD). Characterizing these properties may improve our understanding of proximal junctional kyphosis (PJK; defined as proximal junctional angle [PJA] of >10 deg from UIV-1 to UIV + 2), as well as proximal junctional failure (PJF; symptomatic PJK requiring revision). The purpose of this prospective observational study is to compare biomechanical properties of the PLC in individuals with ASD who do, and do not develop PJK or PJF within 1 year of spinal fusion surgery. Methods Intraoperative biopsies of PLC were obtained from 32 consecutive patients undergoing spinal fusions for ASD (>4 levels). Ligament peak force, tensile stress, tensile strain, and elastic modulus (EM) were measured with a materials testing system. Biomechanical properties and tissue dimensions were correlated with age, gender, BMI, vitamin D level, osteoporosis, sagittal alignment, PJA and change in PJA preoperatively, within 3 months, and at 1 year postoperatively. Results Longer ligaments were associated with greater PJA change at 3 months (p = 0.04), and thinner ligaments were associated with greater PJA change at 1 year (r = 0.57, p = 0.01). Greater EM was associated with greater PJA at both 3 months and 1 year (p = 0.03). Five participants had a change in PJA of >10 1 year postoperatively, and three participants demonstrated PJF. EM was significantly higher in individuals who required revision surgery (p = 0.003), and ligament length was greater (p = 0.03). Preoperative sagittal alignment was not related to incidence of revision surgery (p > 0.10). Conclusions The biomechanical properties of the PLC may be associated with higher risk for proximal failure. Ligaments that are longer, thinner, and less elastic are associated with higher postoperative PJA. Furthermore stiffer EM of the ligament is associated with the need for revision surgery.
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Affiliation(s)
- Micah Blais
- Department of Orthopaedic SurgeryScripps Clinic Medical GroupSan DiegoCaliforniaUSA
| | - Bahar Shahidi
- Department of Orthopaedic SurgeryUC San DiegoLa JollaCaliforniaUSA
| | - Brad Anderson
- Department of Orthopaedic SurgeryUC San DiegoLa JollaCaliforniaUSA
| | - Eli O'Brien
- Department of Orthopaedic SurgeryScripps Clinic Medical GroupSan DiegoCaliforniaUSA
| | - Courtney Moltzen
- Department of Orthopaedic SurgeryScripps Clinic Medical GroupSan DiegoCaliforniaUSA
| | - Tina Iannacone
- Department of Orthopaedic SurgeryScripps Clinic Medical GroupSan DiegoCaliforniaUSA
| | - Robert K. Eastlack
- Department of Orthopaedic SurgeryScripps Clinic Medical GroupSan DiegoCaliforniaUSA
| | - Gregory M. Mundis
- Department of Orthopaedic SurgeryScripps Clinic Medical GroupSan DiegoCaliforniaUSA
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Gonzales-Portillo GS, Mamaril-Davis JC, Riordan K, Avila MJ, Aguilar-Salinas P, Burket A, Dumont T. Evaluation of the Thoracolumbar Injury Classification and Severity (TLICS) Score Over a Two-Year Period at a Level One Trauma Center. Cureus 2023; 15:e43762. [PMID: 37600439 PMCID: PMC10439826 DOI: 10.7759/cureus.43762] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 08/19/2023] [Indexed: 08/22/2023] Open
Abstract
Introduction The use of the Thoracolumbar Injury Classification and Severity Score (TLICS) and other classification systems for guiding the management of traumatic spinal injuries remains controversial. TLICS is one of the few classifications that provides treatment recommendations.We sought to analyze intervention modality selection based on the TLICS scoring system. Methods A retrospective review of patients presenting with traumatic thoracolumbar fractures at a level 1 trauma center over a two-year period was performed. Primary endpoints for comparison analysis included visual analog scale (VAS) scores and Cobb angles during follow-up. Results There were 272 patients with thoracolumbar fractures, of whom 212 had TLICS of ≤3, six with TLICS of 4, and 54 with TLICS of ≥5. Of the 272 total patients, 59 were treated via surgery and 213 via non-surgical conservative methods. The VAS scores significantly decreased from presentation to last follow-up in both surgically treated and conservative groups (p<0.0001). This remained consistent in subgroup analyses of TLICS ≤ 3, TLICS = 4, and TLICS ≥ 5 (p<0.0001). Burst fractures treated conservatively had larger fracture Cobb angles versus those treated via surgery at the last follow-up, although this was not significantly associated (p=0.07). The only significant relationship with Cobb angles was in distraction fractures of the TLICS > 4 conservative group, who had significantly lower Cobb angles at the last follow-up than the TLICS > 4 surgical group (p<0.04). The "surgeon's choice" for TLICS = 4 was surgical intervention (4/6 patients, 66.7%). Conclusion Using the TLICS score, thoracolumbar injuries in a level 1 trauma center are more commonly TLICS ≤ 3. For patients with TLICS = 4, the surgeon's choice was most commonly surgical repair. VAS scores decreased over time from presentation between surgically and conservatively managed patients (as well as within-group analyses). The data concerning Cobb angles were more ambiguous, as larger Cobb angles in burst fractures treated conservatively did not show statistically significant differences with surgery.
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Affiliation(s)
| | | | - Katherine Riordan
- Medicine, The University of Arizona College of Medicine, Tucson, USA
| | - Mauricio J Avila
- Neurosurgery, The University of Arizona College of Medicine, Tucson, USA
| | | | - Aaron Burket
- Neurosurgery, The University of Arizona College of Medicine, Tucson, USA
| | - Travis Dumont
- Neurosurgery, University of Arizona College of Medicine, Tucson, USA
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Wenjie L, Jiaming Z, Weiyu J. The difference and clinical application of modified thoracolumbar fracture classification scoring system in guiding clinical treatment. J Orthop Surg Res 2023; 18:493. [PMID: 37434179 PMCID: PMC10334668 DOI: 10.1186/s13018-023-03958-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 04/10/2023] [Accepted: 06/25/2023] [Indexed: 07/13/2023] Open
Abstract
OBJECTIVE This study aimed to evaluate the feasibility of the modified thoracolumbar injury classification and severity score system in guiding clinical treatment. METHODS A retrospective study was conducted on a cohort of 120 patients with thoracolumbar fractures who were admitted to the Department of Spinal Surgery at Ningbo Sixth Hospital between December 2019 and June 2021. The study population consisted of 68 males and 52 females, with an average age of 36.7 ± 5.7 years. The severity of the fractures was assessed based on comprehensive scores incorporating fracture morphology, neurological function, posterior ligament complex integrity, and disc injury status. The evaluation was performed using the total score T, which guided the formulation of the clinical treatment strategy. Furthermore, the study compared the treatment options, imaging data, and clinical efficacy between two classification systems. RESULTS The analysis of 120 patients revealed no statistically significant difference in the total score or treatment method between the TLICS system and the modified TLICS system. However, the operation rate for the modified TLICS system (73.3%) was slightly lower compared to the TLICS system (79.2%). All patients were followed up for a mean duration of 19.2 ± 4.6 months, ranging from 11 to 27 months. At the last follow-up, the visual analogue scale score was 1.94 ± 0.52, and the modified Japanese Orthopaedic Association score was 28.8 ± 4.5, indicating a significant improvement compared to the scores obtained prior to treatment. The neurological status exhibited varying degrees of improvement. Notably, the anterior vertebral height ratio was 87.10 ± 7.17%, the sagittal index was 90.35 ± 7.72%, and the Cobb angle was 3.05 ± 0.97 degrees at the last follow-up. All these measurements demonstrated statistically significant differences compared to the values observed prior to treatment (P < 0.05). Additionally, two cases of pedicle screw breakage and seven cases of pedicle screw wear and cutting in the vertebral body were observed at the last follow-up, resulting in varying degrees of low back pain. However, no instances of rod breakage were reported. CONCLUSION The modified TLICS system is a practical tool for the classification and assessment of thoracolumbar fractures. It has guiding significance for clinical treatment, and the operation rate was slightly lower than that of TLICS system.
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Affiliation(s)
- Lu Wenjie
- Ningbo Sixth Hospital, Ningbo, 315000, China
| | - Zhang Jiaming
- Zhejiang University of Traditional Chinese Medicine, Hangzhou, 310000, China
| | - Jiang Weiyu
- Ningbo Sixth Hospital, Ningbo, 315000, China.
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Nishida N, Jiang F, Kitazumi R, Yamamura Y, Asano T, Tome R, Kumaran Y, Suzuki H, Funaba M, Ohgi J, Chen X, Sakai T. Finite element analysis of short and long posterior spinal instrumentation and fixation for different pathological thoracolumbar vertebral fractures. World Neurosurg X 2023; 19:100199. [PMID: 37151991 PMCID: PMC10160595 DOI: 10.1016/j.wnsx.2023.100199] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/04/2023] [Accepted: 04/19/2023] [Indexed: 05/09/2023] Open
Affiliation(s)
- Norihiro Nishida
- Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube City, Yamaguchi Prefecture, 755-8505, Japan
- Corresponding author. Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube City, Yamaguchi Prefecture, 755-8505, Japan.
| | - Fei Jiang
- Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube City, Yamaguchi, 755-8611, Japan
| | - Rei Kitazumi
- Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube City, Yamaguchi, 755-8611, Japan
| | - Yuto Yamamura
- Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube City, Yamaguchi, 755-8611, Japan
| | - Takahiro Asano
- Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube City, Yamaguchi, 755-8611, Japan
| | - Rui Tome
- Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube City, Yamaguchi, 755-8611, Japan
| | - Yogesh Kumaran
- Engineering Center for Orthopaedic Research Excellence (E-CORE), Departments of Bioengineering and Orthopaedics, The University of Toledo, Toledo, OH, USA
| | - Hidenori Suzuki
- Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube City, Yamaguchi Prefecture, 755-8505, Japan
| | - Masahiro Funaba
- Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube City, Yamaguchi Prefecture, 755-8505, Japan
| | - Junji Ohgi
- Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube City, Yamaguchi, 755-8611, Japan
| | - Xian Chen
- Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube City, Yamaguchi, 755-8611, Japan
| | - Takashi Sakai
- Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube City, Yamaguchi Prefecture, 755-8505, Japan
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