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Copyright: ©Author(s) 2026.
World J Cardiol. Mar 26, 2026; 18(3): 116299
Published online Mar 26, 2026. doi: 10.4330/wjc.v18.i3.116299
Table 1 Signal pathway and artifact risks
Step
Function
Common artifact sources
Clinical example
GenerationThe heart produces approximately 1 mV currentsCompeting signals from the muscleMyopotential artifacts mimicking atrial fibrillation
DetectionElectrodes capture surface signalsSweat, hair, poor adhesion, movementWandering baseline or false ST elevation (baseline drift)
TransmissionLeads carry signalsCable fracture, patient motion, EMIFlatline due to broken lead; saw-tooth interference from cautery
Amplification and filteringBoosts and cleans signalsAmplifies both signal and noise; filter distortionQRS smoothed, or ST segments flattened, spurious ST shifts
Display and printingTrace presentedAll upstream noise is now visibleArtifact interpreted as ventricular tachycardia, acceleration or deceleration artifacts
Table 2 Classification of electrocardiographic artifacts with examples
Category
Source
ECG appearance
Clinical mimic
Solution
Patient-relatedTremor, shivering, respiration, movementIrregular baseline, wandering driftAF, flutter, VT, ST changesPatient cooperation
Equipment-relatedLoose electrodes, fractured cables, faulty machineBaseline jumps, flatline, spikesAsystole, VFChange cables, better skin preparation, electrode contact
EnvironmentalPower-line hum, cautery, ventilatorsSaw-tooth oscillations, rhythmic noiseFlutter, VTAvoidance of equipment, notch filters
Device-relatedPacemaker, LVAD, neurostimulators, IVLSharp spikes, continuous noiseVF, tachycardiaNot always possible
Table 3 Common clinical mimics of electrocardiographic artifacts
Artifact source
ECG appearance
Clinical mimic
Recognition clues
Tremor (Parkinson’s, shivering)Irregular baseline, absent P wavesAtrial fibrillationP waves marching through; stable pulse
Electrocautery, ventilatorsSaw-tooth baselineAtrial flutterLocalized, no AV conduction ratio
Movement, loose cablesWide irregular complexesVentricular tachycardiaToo fast; QRS visible through noise; stable patient
Loose electrode, EMIChaotic baselineVentricular fibrillationConscious patient; stable SpO2
Respiration, poor skin contactWandering baseline, pseudo ST shiftMyocardial infarctionInconsistent, resolves with repeat
Holter/wearable motionDrop-outs, spikesAV block, tachycardiaCorrelate with activity; not reproducible