Fractional flow reserve guided percutaneous coronary intervention vs coronary artery bypass grafting for multivessel coronary artery disease: A meta-analysis

doi:10.4330/wjc.v17.i9.111044

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Sep 26, 2025 (publication date) through Sep 17, 2025

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

World J Cardiol. Sep 26, 2025; 17(9): 111044
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.111044

Table 1 Study characteristics and patient baseline demographics

Ref.	Study design	Sample size		Age (years)		Sex (male/female)		BMI (kg/m²)		Diabetes		Hypertension		Family history of CAD		Previous (MI)		LVEF ≤ 50% (%)
Ref.	Study design	PCI	CABG	PCI	CABG	PCI	CABG	PCI	CABG	PCI	CABG	PCI	CABG	PCI	CABG	PCI	CABG	PCI	CABG
Dillen et al[14], 2025	RCT	757	743	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Fearon et al[8] 2025	RCT	757	743	65.67 ± 9.66	65.33 ± 8.91	81/19	83/17	28.3	28.1	28	29	71	75	33	29	33	34	18	18
Gioia et al[13], 2020	RCT	205	207	67.35 ± 9.96	67.43 ± 8.35	75.9/24.1	75.2/24.8	29.35	29.09	NA	NA	70.5	70.1	21.6	22.6	11.5	10.7	66.5	66.2

BMI: Body mass index; CAD: Coronary artery disease; LVEF: Left ventricular ejection fraction; MI: Myocardial infarction; PCI: Percutaneous coronary intervention; CABG: Coronary artery bypass grafting; RCT: Randomized controlled trial; NA: Not Applicable.

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Citation: Kataveni S, Ellahi E, Zafar F, Veettil INK, Iqbal A, Dhir B, Sabarish S, Erambalur S, Yathindra MR, Kvn M, Nawaz S, Dudekula SK, Haq UU, Hussain A, Khawar MM. Fractional flow reserve guided percutaneous coronary intervention vs coronary artery bypass grafting for multivessel coronary artery disease: A meta-analysis. World J Cardiol 2025; 17(9): 111044
URL: https://www.wjgnet.com/1949-8462/full/v17/i9/111044.htm
DOI: https://dx.doi.org/10.4330/wjc.v17.i9.111044