Systematic review and meta-analysis: Is surgical cardiac denervation effective against postoperative atrial fibrillation?

doi:10.4330/wjc.v17.i9.110756

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Sep 26, 2025 (publication date) through Sep 17, 2025

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

World J Cardiol. Sep 26, 2025; 17(9): 110756
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.110756

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Figure 1 Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram.

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Figure 2 Forest map. A: Denervation vs no denervation atrial fibrillation; B: Denervation vs no denervation postoperative persistent atrial fibrillation; C: Denervation vs no denervation reoperation for bleeding; D: Denervation vs no denervation transient ischemic attack/stroke; E: Denervation vs no denervation hospital stays (days). CI: Confidence interval.

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Figure 3 Forest map. A: Denervation vs no denervation 30-day mortality; B: Denervation vs no denervation postop blood drainage (mL); C: Denervation vs no denervation postop magnesium (mmol/L); D: Sensitivity analysis of atrial fibrillation (primary outcome); E: Sensitivity analysis of length of hospital stays (days). CI: Confidence interval.

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Figure 4 Risk of bias. A: Assessment of randomized controlled trials done using Risk of Bias 2.0; B: Assessment of non-randomized studies done using the Risk Of Bias In Non-randomized Studies - of Interventions tool. D: Day.

Citation: Bakht D, Amir M, Saleem F, Asif A, Mubashir MM, Farooq AS, Malik MZ, Hassan A, Bakht K, Arham M, Bokhari SFH, Awais MN, Buhadur Ali MK, Dad A, Akram MR. Systematic review and meta-analysis: Is surgical cardiac denervation effective against postoperative atrial fibrillation? World J Cardiol 2025; 17(9): 110756
URL: https://www.wjgnet.com/1949-8462/full/v17/i9/110756.htm
DOI: https://dx.doi.org/10.4330/wjc.v17.i9.110756