Cardiovascular magnetic resonance imaging assessment of outcomes in acute myocardial infarction

doi:10.4330/wjc.v9.i2.109

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World Journal of Cardiology

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World J Cardiol. Feb 26, 2017; 9(2): 109-133
Published online Feb 26, 2017. doi: 10.4330/wjc.v9.i2.109

Cardiovascular magnetic resonance imaging assessment of outcomes in acute myocardial infarction

Jamal N Khan, Gerry P McCann

Jamal N Khan, Gerry P McCann, Department of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Cardiovascular Biomedical Research Unit, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester LE3 9QP, United Kingdom

Author contributions: Khan JN wrote the manuscript; McCann GP critically reviewed and edited the manuscript.

Conflict-of-interest statement: There are no relevant conflicts of interests for the authors with respect to this manuscript or with respect to any manuscripts that the authors may be asked to review.

Correspondence to: Dr. Jamal N Khan, MBChB, PhD, BMedSci, Clinical Research Fellow in Cardiovascular Sciences, Department of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Cardiovascular Biomedical Research Unit, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Groby Road, Leicester LE3 9QP, United Kingdom. jk211@le.ac.uk

Telephone: +44-0116-2044746

Received: October 15, 2016
Peer-review started: October 19, 2016
First decision: November 30, 2016
Revised: December 2, 2016
Accepted: January 2, 2017
Article in press: January 3, 2017
Published online: February 26, 2017
Processing time: 130 Days and 13.5 Hours

Core Tip

Core tip: Cardiovascular magnetic resonance (CMR) imaging uniquely characterizes myocardial and microvascular injury in acute myocardial infarction (AMI). Contrast-enhanced CMR offers robust, validated and reproducible surrogate markers, providing an accurate representation of pathophysiology, assessment of myocardial function and injury, and predictive value for medium to long-term LV function, remodelling and prognosis following primary percutaneous coronary intervention for STEMI. These qualities significantly increase the statistical power of studies using CMR endpoints and has resulted in an exponential increase in AMI studies utilizing CMR based endpoints. An understanding of the role of CMR in the assessment of outcomes in AMI is of key importance not only to interventional and imaging cardiologists, but to the cardiology community as a whole.