©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Nov 26, 2016; 8(11): 623-637
Published online Nov 26, 2016. doi: 10.4330/wjc.v8.i11.623
Published online Nov 26, 2016. doi: 10.4330/wjc.v8.i11.623
Physiology of in-situ arterial revascularization in coronary artery bypass grafting: Preoperative, intraoperative and postoperative factors and influences
T Bruce Ferguson Jr, CV Sciences, East Carolina Heart Institute, East Carolina Diabetes and Obesity Institute, Brody School of Medicine at East Carolina University, Greenville, NC 27615, United States
Author contributions: This manuscript was prepared and written by Ferguson Jr TB.
Conflict-of-interest statement: Dr. Ferguson and his team developed, copyrighted and patented the SPY-QC quantitative flow analyses described in this manuscript along with Novadaq Technologies, Inc. There are no other conflicts to report.
Correspondence to: T Bruce Ferguson Jr, MD, FAHA, FACC, FACS, Professor, CV Sciences, East Carolina Heart Institute, East Carolina Diabetes and Obesity Institute, Brody School of Medicine at East Carolina University, 115 Heart Drive, Greenville, NC 27615, United States. fergusont@ecu.edu
Telephone: +1-252-7442687 Fax: +1-252-7446233
Received: May 1, 2016
Peer-review started: May 3, 2016
First decision: June 17, 2016
Revised: July 7, 2016
Accepted: September 21, 2016
Article in press: September 22, 2016
Published online: November 26, 2016
Processing time: 206 Days and 21.6 Hours
Peer-review started: May 3, 2016
First decision: June 17, 2016
Revised: July 7, 2016
Accepted: September 21, 2016
Article in press: September 22, 2016
Published online: November 26, 2016
Processing time: 206 Days and 21.6 Hours
Core Tip
Core tip: This review examines the emerging understanding of physiology in revascularization from the preoperative, intraoperative and postoperative perspectives. The particular importance of physiology in arterial revascularization, which is becoming the standard of care, is discussed using novel intraoperative imaging data results. These imaging data objectively confirm certain physiologically-determined outcomes, and highlight inadequacies in a number of long-standing assumptions about surgical revascularization with coronary artery bypass grafting.