Vijayvergiya R, Gupta A. Comparison of echocardiography and device based algorithm for atrio-ventricular delay optimization in heart block patients. World J Cardiol 2015; 7(11): 801-807 [PMID: 26635928 DOI: 10.4330/wjc.v7.i11.801]
Corresponding Author of This Article
Dr. Rajesh Vijayvergiya, MD, DM, FSCAI, FISES, FACC, Professor, Department of Cardiology, Advanced Cardiac Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. rajeshvijay999@hotmail.com
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Cardiac & Cardiovascular Systems
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Prospective Study
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Nov 26, 2015 (publication date) through Feb 15, 2026
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World Journal of Cardiology
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1949-8462
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Vijayvergiya R, Gupta A. Comparison of echocardiography and device based algorithm for atrio-ventricular delay optimization in heart block patients. World J Cardiol 2015; 7(11): 801-807 [PMID: 26635928 DOI: 10.4330/wjc.v7.i11.801]
World J Cardiol. Nov 26, 2015; 7(11): 801-807 Published online Nov 26, 2015. doi: 10.4330/wjc.v7.i11.801
Comparison of echocardiography and device based algorithm for atrio-ventricular delay optimization in heart block patients
Rajesh Vijayvergiya, Ankur Gupta
Rajesh Vijayvergiya, Ankur Gupta, Department of Cardiology, Advanced Cardiac Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
Author contributions: All authors were actively involved in management of the index case.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board and Ethics Committee of Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Clinical trial registration statement: The trial was not registered at Clinical Trial Registry-India or any other registry site. For the information please.
Informed consent statement: A written informed consent was taken from all patients for enrolment in the study.
Conflict-of-interest statement: There is no conflict of interest to be declared by both the authors of the manuscript. There is no funding received for the particular study. Authors do not have any financial or intellectual association with any firm/agency which can directly or indirectly affect the results of the study.
Data sharing statement: There is no additional data available related to this study. Hence, there is no possibility of data sharing with any other manuscript.
Correspondence to: Dr. Rajesh Vijayvergiya, MD, DM, FSCAI, FISES, FACC, Professor, Department of Cardiology, Advanced Cardiac Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. rajeshvijay999@hotmail.com
Telephone: +91-172-2756512 Fax: +91-172-2744401
Received: February 8, 2015 Peer-review started: February 9, 2015 First decision: June 4, 2015 Revised: September 9, 2015 Accepted: October 12, 2015 Article in press: October 13, 2015 Published online: November 26, 2015 Processing time: 294 Days and 11.5 Hours
Core Tip
Core tip: Optimization of sensed and paced atrio-ventricular (AV/PV) delay is required for better hemodynamics in patients with complete heart block (CHB). Aim of the present study was to compare the AV/PV delay optimization by echocardiography and intra-cardiac electrocardiogram (IEGM) based QuickOpt algorithm in patients with CHB. We prospectively enrolled 20 patients of CHB who were implanted with a dual chamber pacemaker. A velocity time-integral of left ventricular outflow tract was measured following AV/PV delay optimization by both echocardiography and QuickOpt algorithm method. An agreement between the two techniques was assessed by Bland-Altman analysis. Optimal AV and PV delay as assessed by echocardiography was 155.5 ± 14.68 ms and 122.5 ± 17.73 ms (P < 0.0001), respectively and by QuickOpt method was 167.5 ± 16.73 ms and 117.5 ± 9.10 ms (P < 0.0001), respectively. The time required for AV/PV optimization was 45.26 ± 1.73 min by echocardiography and 0.44 ± 0.08 min by QuickOpt method (P < 0.0001). In conclusion, automated programmer based IEGM method is a quick, easy and reliable alternative to echocardiography for optimization of AV/PV delay in CHB patients.