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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Jan 26, 2015; 7(1): 19-25
Published online Jan 26, 2015. doi: 10.4330/wjc.v7.i1.19
Helicobacter pylori: Does it add to risk of coronary artery disease
Vishal Sharma, Amitesh Aggarwal
Vishal Sharma, Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Amitesh Aggarwal, Department of Medicine, University College of Medical Sciences and GTB Hospital, Delhi 110095, India
Author contributions: Sharma V and Aggarwal A contributed to this paper.
Conflict-of-interest: No conflicts.
Correspondence to: Amitesh Aggarwal, Assistant Professor, Department of Medicine, University College of Medical Sciences and GTB Hospital, Dilshad Garden, New Delhi, Delhi 110095 India. dramitesh@gmail.com
Telephone: +91-98-11060025
Received: October 17, 2014
Peer-review started: October 20, 2014
First decision: November 27, 2014
Revised: December 14, 2014
Accepted: December 29, 2014
Article in press: January 4, 2015
Published online: January 26, 2015
Processing time: 96 Days and 4.3 Hours
Core Tip

Core tip: Coronary artery disease (CAD) is a multifactorial disease and inflammation plays an important role in Atherogenesis. Helicobacter pylori (H. pylori) is speculated to be one organism which may incite the inflammatory response thereby predisposing infected individuals to CAD. This paper looks at clinical evidence in relation to H. pylori infection and CAD and also examines the evidence of effects of eradication of H. pylori on CAD and its risk factors.