Said SA, de Voogt WG, Bulut S, Han J, Polak P, Nijhuis RL, op den Akker JW, Slootweg A. Coronary artery disease in congenital single coronary artery in adults: A Dutch case series. World J Cardiol 2014; 6(4): 196-204 [PMID: 24772259 DOI: 10.4330/wjc.v6.i4.196]
Corresponding Author of This Article
Dr. Salah AM Said, Department of Cardiology, Hospital Group Twente Almelo-Hengelo, Geerdinksweg 141, 7555 DL Hengelo, The Netherlands. samsaid@home.nl
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Original Article
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World J Cardiol. Apr 26, 2014; 6(4): 196-204 Published online Apr 26, 2014. doi: 10.4330/wjc.v6.i4.196
Coronary artery disease in congenital single coronary artery in adults: A Dutch case series
Salah AM Said, Willem G de Voogt, Suat Bulut, Jacques Han, Peter Polak, Rogier LG Nijhuis, Jeroen W op den Akker, Andries Slootweg
Salah AM Said, Rogier LG Nijhuis, Andries Slootweg, Department of Cardiology, Hospital Group Twente Almelo-Hengelo, 7555 DL Hengelo, The Netherlands
Willem G de Voogt, Department of Cardiology, St. Lucas-Andreas Hospital, 1061 AE Amsterdam, The Netherlands
Suat Bulut, Department of Cardiology, Gelre Hospital Zutphen, 7200 GZ Zutphen, The Netherlands
Jacques Han, Department of Cardiology, Hospital De Sionsberg, 9101 DC Dokkum, The Netherlands
Peter Polak, Department of Cardiology, St. Anna Hospital, 5664 EH Geldrop, The Netherlands
Jeroen W op den Akker, Department of Radiodiagnostics, Hospital Group Twente Almelo-Hengelo, 7555 DL Hengelo, The Netherlands
Author contributions: All authors contributed equally to the writing of the manuscript.
Correspondence to: Dr. Salah AM Said, Department of Cardiology, Hospital Group Twente Almelo-Hengelo, Geerdinksweg 141, 7555 DL Hengelo, The Netherlands. samsaid@home.nl
Telephone: +31-74-2905286 Fax: +31-74-2905289
Received: September 15, 2013 Revised: November 6, 2013 Accepted: March 13, 2014 Published online: April 26, 2014 Processing time: 221 Days and 3.8 Hours
Core Tip
Core tip: A Dutch case series of 15 adult patients with congenital isolated single coronary artery (SCA) are presented. Conventional coronary angiography demonstrated congenital isolated SCA originating as a single ostium from the right sinus of Valsalva in 6 patients and originating from the left in 9 patients. SCA may be associated with symptomatic transient transmural myocardial ischemia, non-sustained ventricular tachycardia, and aborted sudden death in the absence or presence of coronary atherosclerosis. The availability of multi-slice computed tomography (MSCT) and cardiovascular magnetic resonance imaging facilitates the delineation of the course of the anomalous vessel. MSCT was helpful to delineate the course of the anomalous artery relative to the aorta and pulmonary artery. Percutaneous coronary intervention was successfully performed in 3 patients. Eight patients were managed medically. Arterial bypass graft was performed in 4 patients with the squeezed SCA. The literature addressing SCA is reviewed.