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Meta-Analysis
Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Cardiol. Aug 26, 2026; 18(8): 123559
Published online Aug 26, 2026. doi: 10.4330/wjc.123559
Impact of pre-existing conduction abnormalities on permanent pacemaker implantation after transcatheter aortic valve replacement: A meta-analysis
Tobias K Fuchs, Cameron Jones, John B Patterson
Tobias K Fuchs, Cameron Jones, Department of Clinical Sciences, Edward Via College of Osteopathic Medicine-Virginia Campus, Blacksburg, VA 24060, United States
John B Patterson, Division of Cardiology, Lewis Gale Physicians, HCA Virginia Health System, Blacksburg, VA 24060, United States
Author contributions: Fuchs TK, Jones C, and Patterson JB designed the study and contributed to its conception, revised the manuscript critically for important intellectual content and approved the final version for submission; Fuchs TK and Jones C performed the literature search, study screening, data extraction, and statistical analysis; Fuchs TK drafted the manuscript; Patterson JB provided supervision; all authors have read and approved the final manuscript.
AI contribution statement: AI tools (specifically OpenAI’s ChatGPT) were used solely for language editing, manuscript organization, and formatting assistance. No AI tool was involved in the generation of research data, interpretation of results, or formulation of conclusions. All AI-generated outputs were critically reviewed and revised by the authors. The authors assume full responsibility for the integrity, accuracy, originality, and scientific validity of all submitted materials.
Conflict-of-interest statement: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Tobias K Fuchs, Doctorate Student, Researcher, Department of Clinical Sciences, Edward Via College of Osteopathic Medicine-Virginia Campus, 2265 Kraft Drive, Blacksburg, Virginia 24060, United States. tfuchs@vcom.edu
Received: May 22, 2026
Revised: July 5, 2026
Accepted: August 20, 2026
Published online: August 26, 2026
Processing time: 97 Days and 2.5 Hours
Core Tip

Core Tip: Baseline right bundle branch block is associated with a 4.52-fold increased odds of permanent pacemaker implantation after transcatheter aortic valve replacement (95%CI: 2.64-7.74; I2 = 50.3%), underscoring the clinical relevance of preprocedural electrocardiographic risk stratification in this population.

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