Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Preventing anthracycline-induced cardiotoxicity with ivabradine: A systematic review and meta-analysis
Rohab Sohail, Ridda Khattak, Haider Hussain Shah, Zaraq Khan, Shafaq Jawed, Asad Ullah Wasim, Bisma Akram, Rohan Patel, Simran Patel, Madihah Alam, Shahryar Chaudhry, Samar Mehdi, Vyom Patel, Manjeet Singh
Rohab Sohail, Ridda Khattak, Rohan Patel, Simran Patel, Madihah Alam, Shahryar Chaudhry, Samar Mehdi, Department of Internal Medicine, Bayhealth Medical Center, Dover, DE 19904, United States
Haider Hussain Shah, Department of Medicine, Bayhealth Hospital, Kent Campus, Dover, DE 19901, United States
Zaraq Khan, Vyom Patel, Department of Internal Medicine, Indiana University School of Medicine, Southwest Internal Medicine Residency Program, Evansville, IN 46202, United States
Shafaq Jawed, Department of Internal Medicine, HCA healthcare system, Houston, TX 77090, United States
Asad Ullah Wasim, Department of Internal Medicine, Northwest Medical Center, Tucson, AZ 85741, United States
Bisma Akram, Department of Medicine, King Edward Medical University, Lahore 54000, Punjab, Pakistan
Manjeet Singh, Department of Cardiology and Cardiovascular Diseases, Bayhealth Medical Center, Dover, DE 19904, United States
Author contributions: Sohail R, Khattak R, Shah HH contributed to conceptualization; Sohail R, Khattak R, Shah HH, Khan Z, Jawed S, Wasim AU, Akram B, Patel R, Patel S, Alam M, Chaudhry S, Mehdi S, and Patel V contributed to writing-original draft; Sohail R and Khattak R contributed to validation; Sohail R contributed to methodology, formal analysis, software; Shah HH contributed to project administration; Patel V contributed to visualization; Singh M contributed to writing-review and editing and supervision.
AI contribution statement: ChatGPT was used for language polishing, translation, and writing assistance. No AI tools were used in data analysis or generation of figures.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article. A similar study abstract has been presented at American Heart Association scientific sessions in 2025; full text has not been published anywhere previously.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Rohab Sohail, MD, Department of Internal Medicine, Bayhealth Medical Center, 640 South State Street, Dover, DE 19904, United States.
rohabsohail98@gmail.com
Received: March 25, 2026
Revised: April 20, 2026
Accepted: May 28, 2026
Published online: July 26, 2026
Processing time: 114 Days and 17.6 Hours
