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Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Oct 26, 2025; 17(10): 111462
Published online Oct 26, 2025. doi: 10.4330/wjc.v17.i10.111462
Cardiomyopathies of endocrine origin: A state-of-the-art review
Jenyfer M Fuentes-Mendoza, Marcio J Concepción-Zavaleta, Juan C Morón-Siguas, Juan M Muñoz-Moreno, Aranza I Pérez-Reyes, Rodrigo Martinez-Galaviz, Raúl D Aguilar-Castañeda, Oziel González-Godoy, Luis A Concepción-Urteaga, José Paz-Ibarra
Jenyfer M Fuentes-Mendoza, Marcio J Concepción-Zavaleta, Grupo de Investigación en Neurociencias, Metabolismo, Efectividad Clínica y Sanitaria (NEMECS), Universidad Científica del Sur, Lima 150142, Peru
Juan C Morón-Siguas, Department of Cardiology, Voto Bernales Hospital, Lima 15072, Peru
Juan C Morón-Siguas, Department of Cardiology, Clínica Internacional, Lima 15023, Peru
Juan M Muñoz-Moreno, Department of Internal Medicine, Macon and Joan Brock Virginia Health Sciences at Old Dominion University, Norfolk, VA 23529, United States
Aranza I Pérez-Reyes, Rodrigo Martinez-Galaviz, Raúl D Aguilar-Castañeda, Oziel González-Godoy, School of Medicine, Universidad Autónoma de San Luis Potosí, San Luis Potosi 78210, Mexico
Luis A Concepción-Urteaga, School of Medicine, Universidad Nacional de Trujillo, Trujillo 13011, La Libertad, Peru
José Paz-Ibarra, School of Medicine, Universidad Nacional Mayor de San Marcos, Lima 15081, Peru
José Paz-Ibarra, Department of Endocrinology, Hospital Nacional Edgardo Rebagliati Martins, Lima 15072, Peru
Co-first authors: Jenyfer M Fuentes-Mendoza and Marcio J Concepción-Zavaleta.
Author contributions: Fuentes-Mendoza JM and Concepción-Zavaleta MJ contributed equally to this work; they conceptualized and designed the review, supervised the process, and made critical revisions; Morón-Siguas JC provided cardiovascular clinical expertise and contributed to interpretation of findings; Muñoz-Moreno JM contributed with international cardiology insight, structural organization, and final review; Pérez-Reyes AI and Martinez-Galaviz R collaborated in literature search, reference verification, and manuscript formatting; Aguilar-Castañeda RD and González-Godoy O assisted in data extraction and synthesis; Concepción-Urteaga LA participated in review supervision and coordinated academic consistency; Paz-Ibarra J conducted the primary literature review, performed data analysis and interpretation, and drafted the original manuscript. All authors reviewed and approved the final submitted version of the manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest related to this work.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marcio J Concepción-Zavaleta, Grupo de Investigación en Neurociencias, Metabolismo, Efectividad Clínica y Sanitaria (NEMECS), Universidad Científica del Sur, Panamericana Sur Highway, Km 19, Villa El Salvador District, Lima 150142, Peru. mconcepcion@cientifica.edu.pe
Received: June 30, 2025
Revised: July 23, 2025
Accepted: September 5, 2025
Published online: October 26, 2025
Processing time: 116 Days and 17.6 Hours
Core Tip

Core Tip: Endocrine cardiomyopathies are an under-recognized but treatable group of heart diseases caused by hormonal imbalances. Timely diagnosis and targeted therapy can reverse cardiac dysfunction and prevent progression to heart failure. Systematic screening for endocrine causes in patients with unexplained cardiomyopathy is essential, and management significantly improves clinical outcomes.