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World J Cardiol. Oct 26, 2025; 17(10): 107750
Published online Oct 26, 2025. doi: 10.4330/wjc.v17.i10.107750
Continuous positive airway pressure therapy for patients with obstructive sleep apnea and coronary artery disease
Thang Viet Luong, Tien Anh Hoang, Duong Hung Tran, Nguyen Nguyen Khoi Pham, Huy Cong Nguyen, Nam Hoang Nhat Le, Hai Nguyen Ngoc Dang
Thang Viet Luong, Tien Anh Hoang, Duong Hung Tran, Nguyen Nguyen Khoi Pham, University of Medicine and Pharmacy, Hue University, Hue 530000, Viet Nam
Thang Viet Luong, Menzies Institute for Medical Research, University of Tasmania, Hobart 7000, Australia
Tien Anh Hoang, Vietnam Society of Sleep Medicine, Hanoi 100000, Vietnam
Huy Cong Nguyen, Department of Internal Medicine, Phuc Hung Private General Hospital, Quang Ngai 570000, Viet Nam
Nam Hoang Nhat Le, Department of Emergency, Tam Anh General Hospital, Ho Chi Minh City 700000, Viet Nam
Hai Nguyen Ngoc Dang, Faculty of Medicine, Duy Tan University, Da Nang 550000, Viet Nam
Co-first authors: Thang Viet Luong and Tien Anh Hoang.
Author contributions: Luong TV and Hoang TA were responsible for conceptualizing the study and writing the original draft of the manuscript; Dang HNN is designated as the corresponding author owing to his specific contributions; Luong TV, Hoang TA, Tran DH, Pham NNK, Nguyen HC, Le NHN, Dang HNN contributed to the writing, reviewing, editing, and drafting of the manuscript and have read and approved the final version; as co-first authors, Luong TV led the data analysis and interpretation, whereas Hoang TA coordinated the research methodology and data collection, with each making essential contributions to the study’s completion.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hai Nguyen Ngoc Dang, MD, Lecturer, Researcher, Faculty of Medicine, Duy Tan University, 254 Nguyen Van Linh, Da Nang 550000, Viet Nam. ngochai123dc@gmail.com
Received: March 31, 2025
Revised: June 7, 2025
Accepted: September 3, 2025
Published online: October 26, 2025
Processing time: 210 Days and 5.4 Hours
Core Tip

Core Tip: Obstructive sleep apnea and coronary artery disease often cooccur, each worsening the other. Continuous positive airway pressure (CPAP) improves obstructive sleep symptoms, but large trials have shown mixed cardiovascular benefits. This review highlights patient profiles most likely to benefit from CPAP and offers guidance for integrating CPAP with lifestyle and medical therapy to optimize outcomes.