Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. Sep 26, 2024; 16(9): 531-541
Published online Sep 26, 2024. doi: 10.4330/wjc.v16.i9.531
Intracoronary thrombolysis combined with drug balloon angioplasty in a young ST-segment elevation myocardial infarction patient: A case report
Li-Qiong She, De-Kui Gao, Le Hong, Yin Tian, Hui-Zhen Wang, Sheng Huang
Li-Qiong She, Department of Critical Care Medicine, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
De-Kui Gao, Le Hong, Sheng Huang, Department of Cardiology, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
Yin Tian, Hui-Zhen Wang, Department of Interventional Medicine, Jiangyou Second People's Hospital, Jiangyou 621701, Sichuan Province, China
Co-first authors: Li-Qiong She and Le Hong.
Author contributions: She LQ, Gao DK and Hong L contributed to manuscript writing; Gao DK and Hong L contributed to manuscript editing and data analysis; Gao DK, She LQ and Wang HZ contributed to data visualization; Tian Y, Wang HZ and Huang S contributed to data collection; She LQ contributed to conceptualization; all authors have read and agreed to the final version for submission. She LQ and Hong L contributed equally to this work as co-first authors.
Supported by Mianyang Health Commission 2019 Scientific Research Encouragement Project, No. 201948.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: De-Kui Gao, Chief Doctor, Department of Cardiology, Jiangyou Second People's Hospital, No. 31 Juhui Road, Jiangyou 621701, Sichuan Province, China. 635651229@qq.com
Received: March 27, 2024
Revised: August 28, 2024
Accepted: September 10, 2024
Published online: September 26, 2024
Processing time: 176 Days and 3.5 Hours
Core Tip

Core Tip: The focus of this report is the emergency management of a young patient with ST-segment elevation myocardial infarction and a history of gastric ulcers. Coronary angiography revealed near-total occlusion of the proximal left anterior descending artery. Primary percutaneous coronary intervention are likely difficult. After discussion with the patient, our strategy was to inject a novel thrombolytic agent (recombinant human prourokinase) via the intracoronary route to dissolve or clear the local thrombus in the coronary artery. Then, a conventional balloon combined with a cutting balloon is used for adequate pre-expansion. Finally, paclitaxel drug-eluting balloon angioplasty was performed, achieving satisfactory short-term and long-term results.