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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. May 26, 2024; 16(5): 231-239
Published online May 26, 2024. doi: 10.4330/wjc.v16.i5.231
Published online May 26, 2024. doi: 10.4330/wjc.v16.i5.231
Management of cerebral amyloid angiopathy and atrial fibrillation: We are still far from precision medicine
Liuba Fusco, Department of Cardiology, University Hospital of Northamptonshire, Northamp
Zefferino Palamà, Department of Cardiology, Casa di Cura Villa Verde, Taranto 70124, Italy
Zefferino Palamà, Antonio Gianluca Robles, Gabriele De Masi De Luca, Silvio Romano, Luigi Sciarra, Department of Life, Health and Environmental Sciences, University of l'Aquila, L'Aquila 67100, Italy
Antonio Scarà, Alessio Borrelli, Department of Cardiology, GVM Care and Research, San Carlo di Nancy Hospital, Rome 00100, Italy
Author contributions: Fusco L, Palamà Z, Scarà A, Borrelli A, Robles AG and De Masi De Luca G analyzed the data, wrote the manuscript; Romano S and Sciarra L revised the text. All authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zefferino Palamà, MD, Research Fellow, Department of Cardiology, Casa di Cura Villa Verde, Taranto 70124, Italy. zefferino.palama@icloud.com
Received: November 18, 2023
Revised: January 29, 2024
Accepted: April 9, 2024
Published online: May 26, 2024
Processing time: 186 Days and 18.6 Hours
Revised: January 29, 2024
Accepted: April 9, 2024
Published online: May 26, 2024
Processing time: 186 Days and 18.6 Hours
Core Tip
Core Tip: The use of anticoagulation therapy could prove to be controversial when trying to balance ischemic stroke and intracranial bleeding risks in patients with concurrent cerebral amyloid angiopathy (CAA) and atrial fibrillation (AF). This review aims to provide an overview of the management of patients with concomitant AF and CAA and proposes the implementation of a risk-based decision-making algorithm.