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Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Cardiol. May 26, 2020; 12(5): 167-191
Published online May 26, 2020. doi: 10.4330/wjc.v12.i5.167
Management of adults with coarctation of aorta
Pradyumna Agasthi, Sai Harika Pujari, Andrew Tseng, Joseph N Graziano, Francois Marcotte, David Majdalany, Farouk Mookadam, Donald J Hagler, Reza Arsanjani
Pradyumna Agasthi, Sai Harika Pujari, Francois Marcotte, David Majdalany, Farouk Mookadam, Reza Arsanjani, Department of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ 85259, United States
Andrew Tseng, Donald J Hagler, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, United States
Joseph N Graziano, Division of Cardiology, Phoenix Children's Hospital, Children's Heart Center, Phoenix, AZ 85016, United States
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflicts of interest reported.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Reza Arsanjani, MD, Associate Professor, Staff Physician, Department of Cardiovascular Diseases, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, United States. arsanjani.reza@mayo.edu
Received: December 23, 2019
Peer-review started: December 23, 2019
First decision: February 20, 2020
Revised: March 21, 2020
Accepted: March 26, 2020
Article in press: March 26, 2020
Published online: May 26, 2020
Processing time: 154 Days and 5.9 Hours
Core Tip

Core tip: Coarctation of the aorta (CoA) is a common congenital cardiac defect with few symptoms and difficult to diagnose. Early diagnosis and treatment are important as long-term data demonstrate reduced life expectancy and increased risk of cardiovascular complications. Surgical repair has traditionally been the mainstay of therapy for correction, although advances in endovascular technology with covered stents and stent grafts permit nonsurgical approaches for the management of children and adults with native CoA and complications. Persistent hypertension and vascular dysfunction can lead to an increased risk of coronary disease, which remains the greatest cause of long-term mortality.