Published online Jul 26, 2021. doi: 10.4330/wjc.v13.i7.211
Peer-review started: October 15, 2020
First decision: March 31, 2021
Revised: April 12, 2021
Accepted: April 29, 2021
Article in press: April 29, 2021
Published online: July 26, 2021
Processing time: 281 Days and 21.8 Hours
The frequency of left ventricular noncompaction cardiomyopathy (LVNC) diagnosis is increasing day by day due to inadequate diagnostic criteria. In addition, the criteria used cannot determine the prognosis and stage of the disease.
New cardiac magnetic resonance (CMR) criteria that can be used in the diagnosis of LVNC can explain when the increased trabeculation rate in healthy individuals can be called disease. In this context, left ventricular function changes due to increased trabeculation may be a parameter.
In our study, it was aimed to evaluate the relationship between LV global and regional function and trabeculation increase. A new parameter that can be used in diagnosis and follow-up will increase the diagnostic specificity of LVNC.
The distribution and ratios of trabeculations in apical, midventricular, and basal regions were examined in CMR. In addition, by using short-axis cine images, regional ejection fraction (EF) and global EF were calculated with the Simpson method in the left ventricle (LV) at apical, basal, and midventricular levels.
Global EF was correlated with apical, midventricular, and basal regional EF, but there was no significant correlation between global EF and the number of trabeculated segments or trabeculation ratio in the global LV. Also, there was no significant correlation between regional EF and the number of trabeculated segments or trabeculation ratio in all three regions.
Global and regional EF changes may be new diagnostic criteria in the diagnosis of LVNC and in the follow-up of the disease.
Studies on the relation of LV segmental functions with trabeculation are limited. Studies with larger cohorts and control groups should be conducted.