Obesity paradox in patients undergoing coronary intervention: A review

doi:10.4330/wjc.v9.i9.731

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 9, Issue 9

This Article

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (8272)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Tables (1-1) series.

Item

Count

PDF

510

WORD

213

HTML

4066

Tables (1-1)

510

Sum=5299

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1144

Download

1819

Sum=2963

Sep 26, 2017 (publication date) through Feb 16, 2026

Times Cited of This Article

Times Cited (14)

Journal Information of This Article

Publication Name

World Journal of Cardiology

ISSN

1949-8462

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Minireviews

World J Cardiol. Sep 26, 2017; 9(9): 731-736
Published online Sep 26, 2017. doi: 10.4330/wjc.v9.i9.731

Obesity paradox in patients undergoing coronary intervention: A review

Nirav Patel, Ossama Elsaid, Abhishek Shenoy, Abhishek Sharma, Samy I McFarlane

Nirav Patel, Ossama Elsaid, Department of Cardiology, Hartford Hospital, Hartford, CT 06001, United States

Abhishek Shenoy, University of Virginia Health System, SUNY Downstate, Brooklyn, NY 11203, United States

Abhishek Sharma, Department of Cardiology, SUNY Downstate, Brooklyn, NY 11203, United States

Samy I McFarlane, Department of Medicine, Division of Endocrinology, SUNY Downstate, Brooklyn, NY 11203, United States

Author contributions: Patel N made substantial contribution in conception, researching literature, designing and writing this manuscript; Shenoy A helped with writing and editing the content; Elsaid O helped with editing the content; Sharma A had important contribution in conception; McFarlane SI was moderator and participated revising it critically and advice to add important intellectual material in this manuscript.

Conflict-of-interest statement: None.

Correspondence to: Nirav Patel, MD, Department of Cardiology, Hartford Hospital, 80 Seymour Street, Hartford, CT 06001, United States. nirav.patel@hhchealth.org

Telephone: +1-860-9726000 Fax: +1-860-6963224

Received: March 13, 2017
Peer-review started: March 14, 2017
First decision: April 20, 2017
Revised: May 8, 2017
Accepted: May 18, 2017
Article in press: May 19, 2017
Published online: September 26, 2017
Processing time: 195 Days and 14.7 Hours

Abstract

There is strong relationship between obesity and cardiovascular disease including coronary artery disease (CAD). However, the literature has shown better outcomes in higher obese patients who undergo percutaneous cardiovascular interventions for CAD, a phenomenon known as the obesity paradox (OX). In this review, we performed extensive search for OX in patients undergoing percutaneous coronary intervention. We also discussed possible mechanism OX and disparities in different race and sex.

Keywords: Obesity paradox; Coronary artery disease; Obesity; Percutaneous coronary intervention; Racial disparities

Core tip: Literatures have shown strong association between obesity and coronary artery disease (CAD). However, a phenomenon known as obesity paradox (OX) exist which means that obese patients who undergo percutaneous coronary intervention for CAD, they have better outcome compared to normal and underweight patients. New studies also suggest racial and sexual disparities in OX. Multiple mechanisms and patho-physiology have been implicated for OX. In this review, we performed literature search of OX undergoing percutaneous intervention, propose mechanism of OX and racial and sexual disparities.