©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Biol Chem. Feb 26, 2016; 7(1): 78-87
Published online Feb 26, 2016. doi: 10.4331/wjbc.v7.i1.78
Published online Feb 26, 2016. doi: 10.4331/wjbc.v7.i1.78
RNA-binding proteins related to stress response and differentiation in protozoa
Lysangela Ronalte Alves, Samuel Goldenberg, Inst. Carlos Chagas, Fiocruz - PR, Curitiba, Parana 81350-010, Brazil
Author contributions: Alves LR and Goldenberg S wrote the paper.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Correspondence to: Samuel Goldenberg, Professor, Inst. Carlos Chagas, Fiocruz - PR, Algacyr Munhoz Madder 3775, Curitiba, Parana 81350-010, Brazil. sgoldenb@fiocruz.br
Telephone: +55-41-33163230
Received: May 29, 2015
Peer-review started: May 29, 2015
First decision: August 19, 2015
Revised: October 25, 2015
Accepted: November 16, 2015
Article in press: November 17, 2015
Published online: February 26, 2016
Processing time: 278 Days and 15.9 Hours
Peer-review started: May 29, 2015
First decision: August 19, 2015
Revised: October 25, 2015
Accepted: November 16, 2015
Article in press: November 17, 2015
Published online: February 26, 2016
Processing time: 278 Days and 15.9 Hours
Core Tip
Core tip: RNA-binding proteins (RBPs) are numerous and widely distributed in nature. In addition to having different domains, these proteins are key modulators of gene expression and are involved in the cellular response to environmental changes, cell differentiation and cell death. In protozoa RBPs are crucial for the rapid gene expression remodeling that occurs in the course of cell differentiation or the stress response.