Abdominosacral resection for locally recurring rectal cancer

Table 1 Patient characteristics and final outcome

Case	Age	Sex	First surgery	Pathological stage	DFS (mo)	OS1 (mo)	OS2 (mo)	Status
1	63	F	ARR	pT3 pN0 M0	103	216	111	DOD (local and lung recurrences)
2	60	F	ARR	pT2 pN0 M0	89	135	41	NED
3	62	F	ARR	pT2 pN0 M0	114	154	34	NED
4	53	F	ARR	pT2 pN1 M0	76	93	22	DOD (local recurrence)
5	46	M	ARR	pT3 pN1 M0 (R1)	12	54	41	DOD (local and lung recurrences)
6	64	F	ARR	pT2 pN0 M0	22	83	57	NED
7	57	F	ARR	pT3 pN2 M0	16	38	13	DOD (liver recurrence)
8	47	M	ARR and liver metastasectomy	pT3 pN1 M1 (liver)	29	47	14	DOD (local recurrence)
9	38	M	ARR	pT2 pN0 M0	49	110	57	NED
10	57	M	ARR	pT2 pN0 M0	17	56	29	NED

¹OS from first surgery to last follow-up or death;

²OS from ASR to last follow-up or death. NED: Non evidence disease; DOD: Dead of disease; DFS: Disease free survival; F: Female; M: Male; ARR: Anterior rectal resection; OS: Overall survival.

Table 2 Treatments for recurrence and complications

	Pre-ASRCT-RT	Surgical procedure	Level of sacrectomy	Procedure lenght (min)	In-hospital stay (d)	Sacral involvement	Early complications(within 30 d)	Late complications(after 30 d)
1	Yes	ASR	S2-S3	380	11	Yes	Neurologic bladder dysfunction	Perineal wound infection and leakage
2	Yes	ASR	S4-S5	400	10	Yes	Pelvic abscess	Uterus/bladder prolapsus
3	Yes	ASR	S2-S3	420	24	Yes	Perineal wound leakage and Neurologic bladder	No
4	No	ASR	S4-S5	370	10	Yes	Perineal wound leakage	No
5	No	ASR	S3-S4	430	93	No	Uretral fistula, perineal flap necrosis and wound leakage	No
6	Yes	ASR	S3-S4	360	25	No	Perineal wound leakage	No
7	CT only	ASR and posterior colpectomy	S3-S4	360	8	No	Perineal wound leakage	Pelvic abscess and ileal fistula
8	No	ASR	S4-S5	480	11	Yes	No	No
9	Yes	ASR	S2-S3	270	9	No	No	No
10	Yes	ASR	S4-S5	330	15	No	Perineal wound infection	No

ASR: Abdomino-sacral resection; CT: Computed tomography.