Long-term outcomes following successful treatment of acute mesenteric ischemic event: A population-based observational study

doi:10.4240/wjgs.118103

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 8

This Article

(4)

(5)

(0)

(51)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 118103
Published online Aug 27, 2026. doi: 10.4240/wjgs.118103

Table 1 Management at initial hospitalization

Management	All	Occlusive					Nonocclusive mesenteric ischemia	Unclear
Management	All	Embolism¹	Thrombosis¹	Unclear¹	Inferior mesenteric artery	Superior mesenteric vein	Nonocclusive mesenteric ischemia	Unclear
Number of patients	203	11	60	36	30	17	12	37
Median age at index hospitalization in years (interquartile range)	74 (64-80)	74 (70-84)	78.5 (70-84)	72.5 (62-82)	77 (65-81)	63 (51-71)	79.5 (69-81)	72 (64-80)
Revascularization	45	7	25	8			1	4
Revascularization and bowel resection	19	1	15	3
Bowel resection	71	3	14	13	12	6	6	17
Conservative treatment	68		6	12	18	11	5	16

¹Superior mesenteric artery.

Full Size Table

Table 2 The 3- and estimated 5-year overall and post-discharge survival and causes of death for subtypes of acute mesenteric ischemia, n (%)

AMI subtype	Overall (including in-hospital deaths) survival (%), 95%CI		Post-discharge survival (%), 95%CI		Causes of death
AMI subtype	3-year	Estimated 5-year	3-year	Estimated 5-year	New AMI event	Other cardiovascular event	Miscellaneous causes of death	Unknown cause of death
SMA embolism	12.8 (5.7-29.1)	12.8 (5.7-29.1)	45.5 (23.8-86.8)	45.5 (23.8-86.8)	-	6 (100.0)	-	-
SMA thrombosis	15.0 (10.6-21.1)	10.8 (7.1-16.4)	46.7 (35.6-61.2)	33.5 (23.2-48.4)	9 (20.0)	17 (37.8)	15 (33.3)	4 (8.9)
SMA unclear occlusion	14.3 (9.2-22.2)	10.7 (6.2-18.5)	47.2 (33.4-66.7)	35.7 (22.3-57.1)	4 (16.0)	10 (40.0)	6 (24.0)	5 (20.0)
Inferior mesenteric artery occlusion	40.0 (27.4-58.5)	30.3 (18.3-50.1)	53.3 (38.2-74.5)	41.3 (26.3-64.7)	-	10 (58.8)	6 (35.3)	1 (5.9)
Superior mesenteric vein occlusion	52.0 (35.7-75.8)	35.5 (28.8-72.0)	76.5 (58.7-99.5)	68.0 (47.9-96.5)	-	1 (20.0)	3 (60.0)	1 (20.0)
Non-occlusive mesenteric ischemia	19.0 (10.2-35.5)	19.0 (10.2-35.5)	66.7 (44.7-99.5)	66.7 (44.7-99.5)	-	2 (50.0)	2 (50.0)	-
Unclear	19.2 (13.3-27.7)	16.3 (10.8-24.6)	62.2 (48.3-79.9)	53.1 (39.0-72.3)	1 (5.0)	8 (40.0)	7 (35.0)	4 (20.0)
P value	P < 0.001	P < 0.001	P = 0.3	P = 0.1	P = 0.278

AMI: Acute mesenteric ischemia; CI: Confidence interval; SMA: Superior mesenteric artery.

Full Size Table

Table 3 Univariable and multivariable analysis evaluating the risk factors for mortality for all patients with acute mesenteric ischemia

Variable	Hazard ratio (95%CI)	P value
Univariable analysis
Sex (female)	0.99 (0.68-1.41)	0.936
Age	1.05 (1.03-1.07)	< 0.001
Disability (yes)	2.95 (2.05-4.24)	< 0.001
Diabetes (yes)	0.95 (0.55-1.64)	0.867
Smoking
Yes	0.57 (0.31-1.06)	0.074
Quit after AMI	0.39 (0.09-1.58)	0.186
Antithrombotic (yes)	0.63 (0.42-0.93)	0.020
Bowel resection (yes)	1.30 (0.68-2.48)	0.422
Age-adjusted Charlson index	1.25 (1.16-1.34)	< 0.001
AMI type
Unclear	0.62 (0.37-1.02)	0.057
IMA occlusion	0.73 (0.43-1.25)	0.248
NOMI	0.31 (0.11-0.85)	0.022
SMV occlusion	0.33 (0.13-0.82)	0.016
Multivariable analysis
Age	1.04 (1.01-1.06)	< 0.001^a
Disability (yes)	1.86 (1.22-2.81)	0.003^a
Smoking
Yes	0.70 (0.37-1.33)	0.275
Quit after AMI	0.49 (0.11-2.17)	0.347
Antithrombotic (yes)	0.40 (0.25-0.63)	< 0.001^a
Age-adjusted Charlson index	1.17 (1.06-1.28)	0.001^a
AMI type
Unclear	0.78 (0.46-1.32)	0.354
IMA occlusion	0.60 (0.34-1.05)	0.073
NOMI	0.19 (0.06-0.56)	0.002^a
SMV occlusion	1.01 (0.39-2.61)	0.983

^aP < 0.05.

AMI: Acute mesenteric ischemia; CI: Confidence interval; IMA: Inferior mesenteric artery; NOMI: Non-occlusive mesenteric ischemia; SMV: Superior mesenteric vein.

Full Size Table

Table 4 Univariable and multivariable analysis evaluating the risk factors for mortality for patients with superior mesenteric artery thrombosis

Variable	Hazard ratio (95%CI)	P value
Univariable analysis
Age	1.04 (1.00-1.07)	0.011
Sex (female)	0.83 (0.45-1.49)	0.527
Disability (yes)	2.74 (1.48-5.08)	0.001
Smoking (yes)	0.71 (0.21-2.31)	0.569
Hypertension (yes)	1.78 (0.62-4.99)	0.279
Atherosclerosis (yes)	0.68 (0.89-4.38)	0.090
Age-adjusted Charlson index	1.16 (1.02-1.31)	0.019
Antithrombotic (yes)	0.29 (0.12-0.64)	0.002
Revascularization (yes)	0.84 (0.45-1.54)	0.565
Bowel resection (yes)	5.06 (1.18-21.53)	0.028
Multivariable analysis
Age	1.02 (0.96-1.08)	0.429
Disability (yes)	6.62 (2.19-20.06)	< 0.001^a
Atherosclerosis (yes)	2.18 (0.51-9.22)	0.288
Antithrombotic (yes)	0.07 (0.01-0.38)	0.002^a
Bowel resection (yes)	1.83 (0.32-10.26)	0.490
Age-adjusted Charlson index	0.90 (0.70-1.16)	0.410

^aP < 0.05. CI: Confidence interval.

Full Size Table

Citation: Kase K, Koitmäe M, Reintam Blaser A, Tamme K, Talving P, Murruste M. Long-term outcomes following successful treatment of acute mesenteric ischemic event: A population-based observational study. World J Gastrointest Surg 2026; 18(8): 118103
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/118103.htm
DOI: https://dx.doi.org/10.4240/wjgs.118103

Kase K, Koitmäe M, Reintam Blaser A, Tamme K, Talving P, Murruste M. Long-term outcomes following successful treatment of acute mesenteric ischemic event: A population-based observational study. World J Gastrointest Surg 2026; 18(8): 118103 [DOI: 10.4240/wjgs.118103]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.